Functionalization of nickel nanowires with a fluorophore aiming at new probes for multimodal bioanalysis
authors Pinheiro, PC; Sousa, CT; Araujo, JP; Guiomar, AJ; Trindade, T
nationality International
journal JOURNAL OF COLLOID AND INTERFACE SCIENCE
author keywords Aluminum oxide template; Nickel nanowires; Ferromagnetic; Surface functionalization; Fluorescence; Polyethyleneimine
keywords MAGNETIC NANOWIRES; BIOLOGICAL APPLICATIONS; NI NANOWIRES; NANOPARTICLES; ARRAYS; SEPARATIONS; SURFACE; NANOMATERIALS; MANIPULATION; FABRICATION
abstract This work reports research on the development of bimodal magnetic and fluorescent 1D nanoprobes. First, ferromagnetic nickel nanowires (NiNW) have been prepared by Ni electrodeposition in an anodic aluminum oxide (AAO) template. The highly ordered self-assembled AAO nanoporous templates were fabricated using a two-step anodization method of aluminum foil. The surface of the NiNW were then modified with polyethyleneimine (PEI) which was previously labeled with an organic dye (fluorescein isothiocyanate: FITC) via covalent bonding. The ensuing functionalized NiNW exhibited the characteristic green fluorescence of FITC and could be magnetically separated from aqueous solutions by using a NdFeB magnet. Finally, the interest of these bimodal NiNW as nanoprobes for in vitro cell separation and biolabeling was preliminary assessed in a proof of principle experiment that involved the attachment of bio-functionalized NiNW to blood cells. (C) 2013 Elsevier Inc. All rights reserved.
publisher ACADEMIC PRESS INC ELSEVIER SCIENCE
issn 0021-9797
year published 2013
volume 410
beginning page 21
ending page 26
digital object identifier (doi) 10.1016/j.jcis.2013.07.065
web of science category Chemistry, Physical
subject category Chemistry
unique article identifier WOS:000325056700003

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