Synthesis, Spectroscopy Studies, and Theoretical Calculations of New Fluorescent Probes Based on Pyrazole Containing Porphyrins for Zn(II), Cd(II), and Hg(II) Optical Detection

authors	Moura, NMM; Nunez, C; Santos, SM; Faustino, MAF; Cavaleiro, JAS; Neves, MGPMS; Capelo, JL; Lodeiro, C
nationality	International
journal	INORGANIC CHEMISTRY
keywords	ION; CHEMOSENSORS; SENSOR; MERCURY; CU2+; DERIVATIVES; LUMINESCENCE; RECOGNITION; COMPLEXES; PLATFORM
abstract	New pyrazole porphyrin conjugates were successfully prepared from a reaction of beta-porphyrin chalcone derivatives with phenylhydrazine in acetic acid followed by an oxidative step. This fast and efficient synthetic approach provided the expected compounds in yields up to 82%. The sensing ability of the new porphyrin-pyrazole derivatives to detect the metal ions Ag+, Na+, K+, Mg2+, Ca2+, Ni2+, Cu2+, Zn2+, Cd2+, Hg2+, Pb2+, and Cr3+ was studied by spectrophotometric and spectrofluorimetric titrations. In the presence of Zn2+, the conjugates exhibit changes in the emission spectra that are desired for a ratiometric-type fluoroionophoric detection probe. The studies were extended to gas phase, where the pyrazole porphyrin conjugates show ability to sense metal ions with high selectivity toward Cu2+ and Ag+, and in poly(methyl methacrylate) doped films with promising results for Zn2+ detection.
publisher	AMER CHEMICAL SOC
issn	0020-1669
year published	2014
volume	53
issue	12
beginning page	6149
ending page	6158
digital object identifier (doi)	10.1021/ic500634y
web of science category	Chemistry, Inorganic & Nuclear
subject category	Chemistry
unique article identifier	WOS:000337557800037
link	24892845