Catalytic alcoholysis of epoxides using metal-free cucurbituril-based solids
authors Bruno, SM; Gomes, AC; Oliveira, TSM; Antunes, MM; Lopes, AD; Valente, AA; Goncalves, IS; Pillinger, M
nationality International
journal ORGANIC & BIOMOLECULAR CHEMISTRY
keywords BETA-ALKOXY ALCOHOLS; SUPRAMOLECULAR CATALYSIS; EFFICIENT CATALYST; ACID CATALYST; OXIDATION
abstract Metal-free cucurbit[7]uril (CB7) solid-state assemblies promote acid-catalysed alcoholysis of aliphatic and aromatic epoxides under mild conditions to give beta-alkoxy alcohols, which are important intermediates for the synthesis of a vast range of compounds such as bioactive pharmaceuticals. The catalytic process is heterogeneous and the catalyst can be reused in consecutive runs without any reactivation treatment. The acid species responsible for the catalytic activity of CB7 may be entrapped hydronium ions.
publisher ROYAL SOC CHEMISTRY
issn 1477-0520
year published 2016
volume 14
issue 16
beginning page 3873
ending page 3877
digital object identifier (doi) 10.1039/c6ob00512h
web of science category Chemistry, Organic
subject category Chemistry
unique article identifier WOS:000374786500004

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