Current Challenges and Perspectives for the Use of Aqueous Plant Extracts in the Management of Bacterial Infections: The Case-Study of Salmonella enterica Serovars

authors	Santos, SAO; Martins, C; Pereira, C; Silvestre, AJD; Rocha, SM
nationality	International
journal	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
author keywords	antimicrobial activity; Salmonella serovars; aqueous plant extracts; bioactive components
keywords	VITRO ANTIMICROBIAL ACTIVITY; SIMILIPAL BIOSPHERE RESERVE; ANTIBACTERIAL ACTIVITY; IN-VITRO; MEDICINAL-PLANTS; ANTIFUNGAL ACTIVITIES; TRADITIONAL MEDICINE; STEM BARK; ANTIINFLAMMATORY ACTIVITIES; ANTIOXIDANT PROPERTIES
abstract	Worldwide, foodborne diseases are a growing public health problem. Among the infectious bacteria, non-typhoidal Salmonella enterica serovars (NTS) are the major cause of hospitalization and death, and the emergence and spread of their antibiotic-resistance is becoming a worldwide health issue. This, coupled with the restrictions of antibiotics use in agriculture and animal production, calls for alternative approaches to solve this problem. Plant-derived aqueous extracts compounds could provide novel straightforward approaches to control pathogenic bacteria. This review discusses the antimicrobial activity of aqueous plant extracts against Salmonella serovars, the possible mechanisms of action involved, which components/structures might be responsible for such activity, and the current challenges for the use of these extracts/components in Salmonella infection management and their application perspectives.
publisher	MDPI
issn	1422-0067
year published	2019
volume	20
issue	4
digital object identifier (doi)	10.3390/ijms20040940
web of science category	Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
subject category	Biochemistry & Molecular Biology; Chemistry
unique article identifier	WOS:000460805400148