Insights into the Nature of Eutectic and Deep Eutectic Mixtures
authors Martins, MAR; Pinho, SP; Coutinho, JAP
nationality International
journal JOURNAL OF SOLUTION CHEMISTRY
author keywords Deep eutectic solvents; Eutectic mixtures; Definitions; Solid-liquid equilibria; Modelling
keywords ACTIVE PHARMACEUTICAL INGREDIENTS; CHOLINE-CHLORIDE; HEAT-CAPACITIES; TRANSDERMAL DELIVERY; ORGANIC-COMPOUNDS; MELTING BEHAVIOR; IONIC LIQUIDS; D-GLUCOSE; SOLVENTS; SOLUBILITY
abstract A stricter definition of a deep eutectic solvent (DES) is urgent, so that it may become a sound basis for further developments in this field. This communication aims at contributing to deepening the understanding of eutectic and deep eutectic mixtures concerning their definition, thermodynamic nature and modelling. The glut of literature on DES applications should be followed by a similar effort to address the fundamental questions on their nature. This hopefully would contribute to correct some widespread misconceptions, and help to establish a stringent definition of what a DES is. DES are eutectic mixtures for which the eutectic point temperature should be lower to that of an ideal liquid mixture. To identify and characterize them, their phase diagrams should be known, in order to compare the real temperature depression to that predicted if ideality is assumed, and to define composition ranges for which they are in the liquid state at operating temperatures. It is also shown that hydrogen bonding between the DES components should not be used to define or characterize a DES, since this would describe many ideal mixtures. The future of deep eutectic solvents is quite promising, and we expect that this work will contribute to the efficient design and selection of the best DES for a given application, and to model properties and phase equilibria without which the process design is impractical.
publisher SPRINGER/PLENUM PUBLISHERS
issn 0095-9782
year published 2019
volume 48
issue 7
beginning page 962
ending page 982
digital object identifier (doi) 10.1007/s10953-018-0793-1
web of science category Chemistry, Physical
subject category Chemistry
unique article identifier WOS:000478750000004
  ciceco authors
  impact metrics
journal analysis (jcr 2017):
journal impact factor 1.401
5 year journal impact factor 1.199
category normalized journal impact factor percentile 22.109
dimensions (citation analysis):
altmetrics (social interaction):



 


Sponsors

1suponsers_list_ciceco.jpg