Biochemical and histopathological impacts of rutile and anatase (TiO2 forms) in Mytilus galloprovincialis
authors Leite, C; Coppola, F; Monteiro, R; Russo, T; Polese, G; Lourenco, MAO; Silva, MRF; Ferreira, P; Soares, AMVM; Freitas, R; Pereira, E
nationality International
journal SCIENCE OF THE TOTAL ENVIRONMENT
author keywords Mussels; Rutile; Anatase; Oxidative stress; Metabolism; Histopathology
keywords OXIDATIVE STRESS; DIGESTIVE GLAND; CRYSTALLINE PHASES; MARINE MUSSELS; NANOPARTICLES; TITANIUM; TOXICITY; EXPOSURE; ACCUMULATION; FRESH
abstract Titanium dioxide (TiO2) particles have been widely used in various industrial applications and consumer products. Due to their large production and use, they will eventually enter into aquatic environments. Once in the aquatic environment TiO2 particles may interact with the organisms and induce toxic effects. Since the most common crystallographic forms of TiO2 are rutile and anatase, the present study evaluated the effect of these two forms of TiO2 particles in Mytilus galloprovincialis. For this, mussels were exposed to different concentrations of rutile and anatase particles (0, 5, 50, 100 mu g/L) for twenty-eight days. Ti concentrations, histopathological alterations and biochemical effects were evaluated. Similar Ti concentrations were found in mussels exposed to rutile and anatase, with the highest values in mussels exposed to the highest exposure concentration. Histopathological results demonstrated that both forms of TiO2 induced alterations on gills and digestive glands along the increasing exposure gradient. Biochemical markers showed that mussels exposed to rutile maintained their metabolic capacity (assessed by the activity of the Electron Transport System, ETS), while anatase increased the metabolism of mussels. Mussels exposed to rutile increased their detoxifying defences which, due to the low tested concentrations, were sufficient to avoid cellular damage. On the other hand, mussels exposed to anatase suffered cellular damages despite the increase of the antioxidant defences which may be related to the high ETS activity. Both rutile and anatase particles were toxic to M. galloprovincialis, being the highest oxidative stress exerted by the crystalline form anatase. (C) 2019 Elsevier B.V. All rights reserved.
publisher ELSEVIER
issn 0048-9697
year published 2020
volume 719
digital object identifier (doi) 10.1016/j.scitotenv.2019.134886
web of science category Environmental Sciences
subject category Environmental Sciences & Ecology
unique article identifier WOS:000521936300024
  ciceco authors
  impact metrics
journal analysis (jcr 2019):
journal impact factor 6.551
5 year journal impact factor 6.419
category normalized journal impact factor percentile 91.887
dimensions (citation analysis):
altmetrics (social interaction):



 


Sponsors

1suponsers_list_ciceco.jpg