A novel hybrid material with calcium and strontium release capability
authors Castro, AGB; Almeida, JC; Salvado, IMM; Margaca, FMA; Fernandes, MHV
nationality International
journal MATERIALS LETTERS
author keywords Sol-gel preparation; Biomaterials; Electron Microscopy; Microstructure; FTIR
keywords IN-VITRO; FT-IR; RANELATE; BIOACTIVITY; HYDROLYSIS; DRUG
abstract The preparation of PDMS-TEOS-CaO hybrid materials by sol-gel techniques has been widely described in previous works. Calcium nitrate is the most common source of calcium used in these preparations. However, to remove possible toxic nitrate by-products a thermal treatment is necessary at temperatures above 500 degrees C, which leads to the degradation of the polymeric components of the hybrids. Strontium has already shown some promising results in the therapeutic area, being used in cases of osteoporosis and low bone density. In this study a new potential bioactive hybrid material was prepared, by sol-gel techniques, using calcium acetate as a novel calcium source. Also, for the first time, incorporation of strontium in a PDMS-TEOS hybrid system was evaluated. Samples were characterized before and after immersion in Kokubo's Simulated Body Fluid (SBF) by SEM, EDS, ICP and FT-IR spectroscopy. (C) 2012 Elsevier B.V. All rights reserved.
publisher ELSEVIER SCIENCE BV
issn 0167-577X
year published 2012
volume 88
beginning page 12
ending page 15
digital object identifier (doi) 10.1016/j.matlet.2012.08.022
web of science category Materials Science, Multidisciplinary; Physics, Applied
subject category Materials Science; Physics
unique article identifier WOS:000310423700004
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journal analysis (jcr 2017):
journal impact factor 2.687
5 year journal impact factor 2.452
category normalized journal impact factor percentile 68.173
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