|
authors |
Estrada, AC; Daniel-da-Silva, AL; Trindade, T |
|
nationality |
International |
|
journal |
RSC ADVANCES |
|
keywords |
NEAR-INFRARED LIGHT; IN-VITRO; DELIVERY; NANOPARTICLES; SYSTEMS; SINGLE; NANOMATERIALS; IRRADIATION; CHALLENGES; POLYMERS |
|
abstract |
Temperature and near infrared (NIR) light responsive multi-walled carbon nanotube (MWCNT)-kappa-carrageenan hydrogel composites have been prepared. The effects of the MWCNTs on the microstructure, strength, swelling and release properties of the resultant materials were investigated. MWCNTs acted as reinforcing fillers and enhanced the mechanical properties of the hydrogels, the effect being mostly nanotube concentration dependent. Surface functionalization of nanotubes had a major influence on the swelling of the composites. The increased release of a model drug (methylene blue) in in vitro conditions, from kappa-carrageenan hydrogel composites due to the NIR photothermal effect of MWCNTs was demonstrated at the physiological temperature. Thus, these composites are promising materials for the development of carriers for remotely activated drug delivery. |
|
publisher |
ROYAL SOC CHEMISTRY |
|
issn |
2046-2069 |
|
year published |
2013 |
|
volume |
3 |
|
issue |
27 |
|
beginning page |
10828 |
|
ending page |
10836 |
|
digital object identifier (doi) |
10.1039/c3ra40662h |
|
web of science category |
Chemistry, Multidisciplinary |
|
subject category |
Chemistry |
|
unique article identifier |
WOS:000320467500036
|
