|
authors |
Pinho, SLC; Amaral, JS; Wattiaux, A; Duttine, M; Delville, MH; Geraldes, CFGC |
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nationality |
International |
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journal |
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY |
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author keywords |
Nanoparticles; Lanthanides; Orthoferrites; Relaxivity; Imaging agents |
|
keywords |
MULTIFUNCTIONAL MAGNETIC NANOPARTICLES; IRON-OXIDE NANOPARTICLES; PEROVSKITE-TYPE OXIDES; MRI CONTRAST AGENTS; MOSSBAUER-SPECTROSCOPY; HYDROTHERMAL SYNTHESIS; THERMAL-DECOMPOSITION; GD2O3 NANOPARTICLES; GADOLINIUM OXIDE; THIN-FILMS |
|
abstract |
A combination of sol-gel synthesis and thermal decomposition was developed for preparing nanosized, perovskite-type LnFeO(3) (Ln = Eu, Gd, Tb) powders. Perovskite-type powders with crystalline particles of 100 nm average size, as determined by transmission electron microscopy (TEM), could be obtained after a thermal treatment at 800 degrees C. The perovskite nanoparticles (NPs) were further characterized by X-ray powder diffraction and Mossbauer spectroscopy. These were in agreement with the pure perovskite LnFeO(3) structure with the expected Zeeman sextet corresponding to a magnetically ordered phase. Magnetization measurements [M(H)] at 5 K and 300 K showed a behavior that is dominated by antiferromagnetic interactions and weak ferromagnetism in EuFeO3, while for Ln = Gd, Tb, they were dominated by the low ordering temperature Ln magnetic sublattice. The colloidal aqueous NPs suspensions exhibited no significant leaching of free Ln(3+) ions. Their relaxivities define them as potential T-2 MRI contrast agents for further biomedical applications. The NPs showed fast uptake and no cytotoxicity at concentrations below 62.5 mu g/mL with respect to Hela cells. |
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publisher |
WILEY-V C H VERLAG GMBH |
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issn |
1434-1948 |
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year published |
2018 |
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issue |
31 |
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beginning page |
3570 |
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ending page |
3578 |
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digital object identifier (doi) |
10.1002/ejic.201800468 |
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web of science category |
Chemistry, Inorganic & Nuclear |
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subject category |
Chemistry |
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unique article identifier |
WOS:000442492500006
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