authors |
Pinho, SLC; Amaral, JS; Wattiaux, A; Duttine, M; Delville, MH; Geraldes, CFGC |
nationality |
International |
journal |
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY |
author keywords |
Nanoparticles; Lanthanides; Orthoferrites; Relaxivity; Imaging agents |
keywords |
PEROVSKITE-TYPE OXIDES; MRI CONTRAST AGENTS; MULTIFUNCTIONAL MAGNETIC NANOPARTICLES; FE-57 MOSSBAUER-SPECTROSCOPY; BIOMEDICAL APPLICATIONS; THIN-FILMS; HYDROTHERMAL SYNTHESIS; THERMAL-DECOMPOSITION; GD2O3 NANOPARTICLES; COMBUSTION METHOD |
abstract |
A combination of sol-gel synthesis and thermal decomposition was developed for preparing nanosized, perovskite-type LnFeO(3) (Ln = Eu, Gd, Tb) powders. Perovskite-type powders with crystalline particles of 100 nm average size, as determined by transmission electron microscopy (TEM), could be obtained after a thermal treatment at 800 degrees C. The perovskite nanoparticles (NPs) were further characterized by X-ray powder diffraction and Mossbauer spectroscopy. These were in agreement with the pure perovskite LnFeO(3) structure with the expected Zeeman sextet corresponding to a magnetically ordered phase. Magnetization measurements [M(H)] at 5 K and 300 K showed a behavior that is dominated by antiferromagnetic interactions and weak ferromagnetism in EuFeO3, while for Ln = Gd, Tb, they were dominated by the low ordering temperature Ln magnetic sublattice. The colloidal aqueous NPs suspensions exhibited no significant leaching of free Ln(3+) ions. Their relaxivities define them as potential T-2 MRI contrast agents for further biomedical applications. The NPs showed fast uptake and no cytotoxicity at concentrations below 62.5 mu g/mL with respect to Hela cells. |
publisher |
WILEY-V C H VERLAG GMBH |
issn |
1434-1948 |
year published |
2018 |
issue |
31 |
beginning page |
3570 |
ending page |
3578 |
digital object identifier (doi) |
10.1002/ejic.201800468 |
web of science category |
Chemistry, Inorganic & Nuclear |
subject category |
Chemistry |
unique article identifier |
WOS:000442492500006
|