Light Penetration and Photoisomerization in Rhodopsin studied by Numerical Simulations and Double - Quantum Solid - State NMR
authors M. Concistrè, A. Gansmüller, N. McLean, O. G. Johannessen, I. Marín Montesinos, P. H. M. Bovee- Geurts, R. C. D. Brown, W. J. DeGrip and M. H. Levitt,
nationality International
journal Journal of the American Chemical Society
abstract The penetration of light into optically thick samples containing the G-protein-coupled receptor rhodopsin is studied by numerical finite-element simulations and double-quantum solid-state NMR experiments. Illumination with white light leads to the generation of the active bathorhodopsin photostate in the outer layer of the sample but generates a large amount of the side product, isorhodopsin, in the sample interior. The overall yield of bathorhodopsin is improved by using monochromatic 420 nm illumination and by mixing the sample with transparent glass beads. The implications of these findings on the interpretation of previously published rhodopsin NMR data are discussed.
year published 2009
volume 131
beginning page 6133
digital object identifier (doi) 10.1021/ja809878c
  ciceco authors
  impact metrics
journal analysis (jcr 2019):
journal impact factor 14.612
5 year journal impact factor 14.549
category normalized journal impact factor percentile 92.938
dimensions (citation analysis):
altmetrics (social interaction):