Silylation of bacterial cellulose to design membranes with intrinsic antibacterial properties
authors Chantereau, G; Brown, N; Dourges, MA; Freire, CSR; Silvestre, AJD; Sebe, G; Coma, V
nationality International
journal CARBOHYDRATE POLYMERS
author keywords Bacterial cellulose; Nanocellulose; Aminosilane; Anti-bacterial; Silylation
keywords SURFACE FUNCTIONALIZATION; BIOCELLULOSE MEMBRANES; MICROBIAL CELLULOSE; NANOCELLULOSE
abstract In this work, we report a convenient method of grafting non-leachable bioactive amine functions onto the surface of bacterial cellulose (BC) nanofibrils, via a simple silylation treatment in water. Two different silylation protocols, involving different solvents and post-treatments were envisaged and compared, using 3-aminopropyltrimethoxysilane (APS) and (2-aminoethyl)-3-aminopropyl-trimethoxysilane (AEAPS) as silylating agents. In aqueous and controlled conditions, water-leaching resistant amino functions could be successfully introduced into BC, via a simple freeze-drying process. The silylated material remained highly porous, hygroscopic and displayed sufficient thermal stability to support the sterilization treatments generally required in medical applications. The impact of the silylation treatment on the intrinsic anti-bacterial properties of BC was investigated against the growth of Escherichia coli and Staphylococcus aureus. The results obtained after the in vitro studies revealed a significant growth reduction of S. aureus within the material.
publisher ELSEVIER SCI LTD
issn 0144-8617
year published 2019
volume 220
beginning page 71
ending page 78
digital object identifier (doi) 10.1016/j.carbpol.2019.05.009
web of science category Chemistry, Applied; Chemistry, Organic; Polymer Science
subject category Chemistry; Polymer Science
unique article identifier WOS:000470825500008
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journal analysis (jcr 2017):
journal impact factor 5.158
5 year journal impact factor 5.326
category normalized journal impact factor percentile 93.599
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