Salt pan brine water as a sustainable source of sulphated polysaccharides with immunostimulatory activity
authors Nunes, C; Rocha, A; Quiterio, P; Ferreira, SS; Correia, A; Vilanova, M; Coimbra, MA
nationality International
journal INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
keywords MARINE POLYSACCHARIDES; CHEMICAL METHODS; MELANOIDINS; MANNANS; WALLS; ALGAE
abstract Marine environments are an enormous source of materials with biological interest, such as sulphated polysaccharides, which have relevant biological activities. In this study the potential of salt pan brine water as an easily accessible source of sulphated polysaccharides was evaluated. This water revealed to have a high quantity of polymeric material, five times more than sea water, mainly composed by highly sulphated polysaccharides. Structural analysis identified a diversity of polysaccharides, namely rhamnans, fucans, mannans, xylomannans, glucuronomannans, galactans, and glucans. All these structures seem to form complexes that are resistant to the salt pan conditions along salt production. These polysaccharides showed in vitro stimulatory activity for B cells, suggesting their potential application in nutraceutical and biomedical fields. Salt pan brine water is a valuable source of environmentally friendly and low-cost available bioactive compounds prone to be exploited. (C) 2019 Elsevier B.V. All rights reserved.
publisher ELSEVIER
issn 0141-8130
isbn 1879-0003
year published 2019
volume 133
beginning page 235
ending page 242
digital object identifier (doi) 10.1016/j.ijbiomac.2019.04.021
web of science category Biochemistry & Molecular Biology; Chemistry, Applied; Polymer Science
subject category Biochemistry & Molecular Biology; Chemistry; Polymer Science
unique article identifier WOS:000472685700027
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journal analysis (jcr 2019):
journal impact factor 5.162
5 year journal impact factor 5.137
category normalized journal impact factor percentile 86.689
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