authors |
Eddahmi, M; Moura, NMM; Bouissane, L; Gamouh, A; Faustino, MAF; Cavaleiro, JAS; Paz, FAA; Mendes, RF; Lodeiro, C; Santos, SM; Neves, MGPMS; Rakib, E |
nationality |
International |
journal |
NEW JOURNAL OF CHEMISTRY |
keywords |
BIOLOGICAL EVALUATION; ANHYDROUS SNCL2; DERIVATIVES; INDAZOLES; HYDROGEN; REDUCTION; ARYNES; KETO |
abstract |
New N-alkyl-nitroindazolylacetonitriles were efficiently obtained via vicarious nucleophilic substitution of N-methyl-nitroindazoles with 4-chlorophenoxyacetonitrile. All compounds were fully characterized by NMR and mass spectroscopy techniques and the structures of some of them were additionally confirmed by X-ray diffraction analysis data. Tautomeric switching was observed in this series of nitroindazolylacetonitriles upon addition of basic anions followed by UV-Vis spectrophotometric and H-1-NMR titrations. The formation of tautomeric species induced by anionic species was endorsed by Density Functional Theory calculations. |
publisher |
ROYAL SOC CHEMISTRY |
issn |
1144-0546 |
isbn |
1369-9261 |
year published |
2019 |
volume |
43 |
issue |
36 |
beginning page |
14355 |
ending page |
14367 |
digital object identifier (doi) |
10.1039/c9nj02807b |
web of science category |
Chemistry, Multidisciplinary |
subject category |
Chemistry |
unique article identifier |
WOS:000486223200015
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ciceco authors
impact metrics
journal analysis (jcr 2019):
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journal impact factor |
3.288 |
5 year journal impact factor |
3.153 |
category normalized journal impact factor percentile |
61.864 |
dimensions (citation analysis):
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altmetrics (social interaction):
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