Biomedical applications of laminarin
authors Zargarzadeh, M; Amaral, AJR; Custodio, CA; Mano, JF
nationality International
journal CARBOHYDRATE POLYMERS
author keywords Laminarin; Beta-glucan; Seaweed; Anti-tumor; Tissue engineering; Antioxidant
keywords IN-VITRO; ANTICANCER ACTIVITY; BETA-GLUCAN; MARINE POLYSACCHARIDES; ANTIOXIDANT ACTIVITIES; CELL-ADHESION; BROWN; EXTRACTION; ANTITUMOR; ALGAE
abstract The ocean is par excellence a fertile territory of biodiversity on our planet. Marine-derived polysaccharides have been applied as functional materials in biomedicine due to their attractive bioactive properties, safety, high availability and low-cost production. Laminarin (or laminaran), a low molecular weight beta-glucan storage polysaccharide present in brown algae, can be (bio-) chemically modified to enhance its biological activity and employed in cancer therapies, drug/gene delivery, tissue engineering, antioxidant and anti-inflammatory functions. This review provides a brief overview on laminarin characteristics, modification strategies and highlights its pivotal biomedical applications.
publisher ELSEVIER SCI LTD
issn 0144-8617
isbn 1879-1344
year published 2020
volume 232
digital object identifier (doi) 10.1016/j.carbpol.2019.115774
web of science category Chemistry, Applied; Chemistry, Organic; Polymer Science
subject category Chemistry; Polymer Science
unique article identifier WOS:000507231800004
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  impact metrics
journal analysis (jcr 2019):
journal impact factor 7.182
5 year journal impact factor 6.89
category normalized journal impact factor percentile 96.638
dimensions (citation analysis):
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