Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers
authors Castro, KADF; Costa, LD; Guieu, S; Biazzotto, JC; Neves, MDPMS; Faustino, MAF; da Silva, RS; Tome, AC
nationality International
journal PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
keywords SINGLET OXYGEN GENERATION; BODIPY DYES; AZADIPYRROMETHENE COMPLEXES; PHOTOPHYSICAL PROPERTIES; THERAPY; NANOPARTICLES; ACCEPTORS; ZINC
abstract In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most photo-toxic (at 2.5 mu M) towards B16F10 cells.
publisher ROYAL SOC CHEMISTRY
issn 1474-905X
year published 2020
volume 19
issue 7
beginning page 885
ending page 891
digital object identifier (doi) 10.1039/d0pp00114g
web of science category Biochemistry & Molecular Biology; Biophysics; Chemistry, Physical
subject category Biochemistry & Molecular Biology; Biophysics; Chemistry
unique article identifier WOS:000548627600012
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journal analysis (jcr 2019):
journal impact factor 2.831
5 year journal impact factor 2.667
category normalized journal impact factor percentile 50.433
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