In Vitro performance assessment of new brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements
authors Pina, S; Vieira, SI; Torres, PMC; Goetz-Neunhoeffer, F; Neubauer, J; Silva, OABDE; Silva, EFDE; Ferreira, JMF
nationality International
journal JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
author keywords brushite cement; setting time; mechanical strength; cytotoxicity
keywords CALCIUM-PHOSPHATE CEMENT; TO-POWDER RATIO; TRICALCIUM PHOSPHATE; BIPHASIC HYDROXYAPATITE; OSTEOBLASTIC CELLS; CRYSTAL-STRUCTURE; APATITE CEMENT; STRONTIUM; INJECTABILITY; VIVO
abstract The present study investigated the in vitro performance of brushite-forming Zn- and ZnSr-substituted beta-TCP bone cements in terms of wet mechanical strength and biological response. Quantitative phase analysis and structural refinement of the powdered samples were performed by Xray powder diffraction and Rietveld refinement technique. Initial and final setting times of the cement pastes, measured using Gilmore needles technique, showed that ZnSrCPC sets faster than ZnCPC. The measured values of the wet strength after 48 h of immersion in PBS solution at 37 degrees C showed that ZnSrCPC cements are stronger than ZnCPC cements. Human osteosarcoma-derived MG63 cell line proved the nontoxicity of the cement powders, using the resazurin metabolic assay. (C) 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 948: 414-420, 2010.
publisher WILEY-BLACKWELL
issn 1552-4973
year published 2010
volume 94B
issue 2
beginning page 414
ending page 420
digital object identifier (doi) 10.1002/jbm.b.31669
web of science category Engineering, Biomedical; Materials Science, Biomaterials
subject category Engineering; Materials Science
unique article identifier WOS:000280009900017
  ciceco authors
  impact metrics
journal analysis (jcr 2017):
journal impact factor 3.373
5 year journal impact factor 3.104
category normalized journal impact factor percentile 68.969
dimensions (citation analysis):
altmetrics (social interaction):



 


Apoio

1suponsers_list_ciceco.jpg