|
authors |
Tinoco, MT; Ramos, P; Candeias, MF |
|
nationality |
International |
|
journal |
FITOTERAPIA |
|
author keywords |
Laurus novocanariensis; Ethanol; Stomach; Liver; Alcohol dehydrogenase; Catalase |
|
keywords |
GASTROINTESTINAL-TRACT; SESQUITERPENE LACTONE; BAY LEAF; NOBILIS; COSTUNOLIDE; TERPENOIDS; ELEVATION |
|
abstract |
A hexane extract from the leaves of Laurus novocanariensis was investigated for its activity on ethanol metabolism in Wistar rats. The extract could interfere with blood ethanol elevation, the induction of gastric alcohol dehydrogenase (ADH) and the reduction of erythrocyte catalase (CAT). The sesquiterpene lactones dehydrocostus lactone and costunolide were identified in the active extract, and might represent its active constituents. These results support the use of L novocanariensis in the traditional Madeira Island medicine to protect against ethanol injury. (C) 2009 Elsevier B.V. All rights reserved. |
|
publisher |
ELSEVIER SCIENCE BV |
|
issn |
0367-326X |
|
year published |
2009 |
|
volume |
80 |
|
issue |
2 |
|
beginning page |
130 |
|
ending page |
133 |
|
digital object identifier (doi) |
10.1016/j.fitote.2008.12.003 |
|
web of science category |
Chemistry, Medicinal; Pharmacology & Pharmacy |
|
subject category |
Pharmacology & Pharmacy |
|
unique article identifier |
WOS:000264520700011
|
