Effects of a hexane extract from Laurus novocanariensis leaves on the ethanol metabolism of Wistar rats
authors Tinoco, MT; Ramos, P; Candeias, MF
nationality International
journal FITOTERAPIA
author keywords Laurus novocanariensis; Ethanol; Stomach; Liver; Alcohol dehydrogenase; Catalase
keywords GASTROINTESTINAL-TRACT; SESQUITERPENE LACTONE; BAY LEAF; NOBILIS; COSTUNOLIDE; TERPENOIDS; ELEVATION
abstract A hexane extract from the leaves of Laurus novocanariensis was investigated for its activity on ethanol metabolism in Wistar rats. The extract could interfere with blood ethanol elevation, the induction of gastric alcohol dehydrogenase (ADH) and the reduction of erythrocyte catalase (CAT). The sesquiterpene lactones dehydrocostus lactone and costunolide were identified in the active extract, and might represent its active constituents. These results support the use of L novocanariensis in the traditional Madeira Island medicine to protect against ethanol injury. (C) 2009 Elsevier B.V. All rights reserved.
publisher ELSEVIER SCIENCE BV
issn 0367-326X
year published 2009
volume 80
issue 2
beginning page 130
ending page 133
digital object identifier (doi) 10.1016/j.fitote.2008.12.003
web of science category Chemistry, Medicinal; Pharmacology & Pharmacy
subject category Pharmacology & Pharmacy
unique article identifier WOS:000264520700011
  ciceco authors
  impact metrics
journal analysis (jcr 2019):
journal impact factor 2.527
5 year journal impact factor 2.906
category normalized journal impact factor percentile 41.207
dimensions (citation analysis):
altmetrics (social interaction):



 


Apoio

1suponsers_list_ciceco.jpg