Additive manufacturing of 3D porous alkali-free bioactive glass scaffolds for healthcare applications
authors Olhero, SM; Fernandes, HR; Marques, CF; Silva, BCG; Ferreira, JMF
nationality International
journal JOURNAL OF MATERIALS SCIENCE
keywords CALCIUM-PHOSPHATE SCAFFOLDS; MECHANICAL-PROPERTIES; CERAMIC SCAFFOLDS; PARTICLE-PACKING; IN-VITRO; TISSUE; SUSPENSIONS; RHEOLOGY; BIOCERAMICS; SIZE
abstract This work deals with the fabrication by robocasting of 3D porous scaffolds of an alkali-free bioactive glass composition, FastOs (R) BG, belonging to the diopside (CaMgSi2O6)-fluorapatite (Ca-5(PO4)(3)F)-tricalcium phosphate (Ca-3(PO4)(2)) system. A glass frit prepared by melt quenching was grinded by dry and wet milling up to getting a suitable combination of particle sizes. The milled frit was then dispersed in aqueous media with the addition of a polycarbonate dispersant, hydroxypropyl methylcellulose (HPMC) as binder and Aristoflex (R) TAC as gelation agent. The effects of the type and amounts of the processing additives and particle size distribution on the rheological properties of the extrudable pastes were investigated. Printable inks containing 47 vol.% solids with rheological properties tuned to meet the stringent requirements of robocasting technique were obtained. Scaffolds with totally interconnected 3D pore networks and different pore sizes (200, 300 and 500 mu m) could be easily fabricated and sintered. The excellent processing and sintering ability resulted in compressive strength values comparable to that of cancellous bone essential for 3D porous scaffolds intended for bone regeneration and tissue engineering applications.
publisher SPRINGER
issn 0022-2461
year published 2017
volume 52
issue 20
beginning page 12079
ending page 12088
digital object identifier (doi) 10.1007/s10853-017-1347-4
web of science category Materials Science, Multidisciplinary
subject category Materials Science
unique article identifier WOS:000406391600023
  ciceco authors
  impact metrics
times cited (wos core): 0
journal impact factor (jcr 2016): 2.599
5 year journal impact factor (jcr 2016): 2.522
category normalized journal impact factor percentile (jcr 2016): 68.182
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