Organotins: Sources and Impacts on Health and Environment
authors Sousa ACA, Tanabe S, Pastorinho MR
nationality International
journal Reference Module in Earth Systems and Environmental Sciences
abstract Organotin compounds are used as biocides, plastic stabilizers, and catalysts for the production of polyurethanes and silicones. Their notoriety is due to tributyltin (TBT), a potent biocide extensively used in antifouling paints until the beginning of the 21st century. As a consequence of its widespread use, TBT was responsible for the contamination of the marine environment at a global scale, causing several deleterious effects toward nontarget organisms, including imposex in gastropods, which is still considered the best example of endocrine disruption in wildlife. In mammals, including humans, organotins' negative effects comprise cardiotoxicity, neurotoxicity, immunotoxicity, and endocrine/metabolic dysfunction, including obesity.
publisher Elsevier
year published 2017
digital object identifier (doi) 10.1016/B978-0-12-409548-9.09986-3
link http://dx.doi.org/10.1016/B978-0-12-409548-9.09986-3
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