Robocasting of ceramic glass scaffolds: Sol-gel glass, new horizons
authors Ben-Arfa, BAE; Neto, AS; Palama, IE; Salvado, IMM; Pullar, RC; Ferreira, JMF
nationality International
journal JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
author keywords Sol-gel; Bioactive glass; Suspension rheology; Robocasting 3D scaffolds; Cytotoxicity
keywords BIOACTIVE GLASS; MECHANICAL-PROPERTIES; CALCIUM PHOSPHATES; 45S5; CRYSTALLIZATION; BIODEGRADATION; BEHAVIOR
abstract This article reports the first robocasting of a sol-gel based glass ceramic scaffold. Sol-gel bioactive glass powders usually exhibit high volume fractions of meso- and micro-porosities, bad for colloidal processing as this adsorbs significant portion of the dispersing medium, affecting dispersion and flow. We circumvent these practical difficulties, to achieve pastes with particle size distributions, high solids loading and appropriate rheological properties for extrusion through fine nozzles for robocasting. Scaffolds with different macro-pore sizes (300-500 mu m) with solid loadings up to 40 vol.% were robocast. The sintered (800 degrees C, 2 h) scaffolds exhibited compressive strength of 2.5-4.8 MPa, formed hydroxyapatite after 72 h in SBF, and had no cytotoxicity and a considerable MG63 cells viability rate. These features make the scaffolds promising candidates for tissue engineering applications and worthy for further in vivo investigations.
publisher ELSEVIER SCI LTD
issn 0955-2219
year published 2019
volume 39
issue 4
beginning page 1625
ending page 1634
digital object identifier (doi) 10.1016/j.jeurceramsoc.2018.11.019
web of science category Materials Science, Ceramics
subject category Materials Science
unique article identifier WOS:000457819600114
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journal impact factor 3.794
5 year journal impact factor 3.536
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