[Ga3+8Sm3+2, Ga3+8Tb3+2] metallacrowns are highly promising ratiometric luminescent molecular nanothermometers operating at physiologically relevant temperatures
authors Elvin V. Salerno, Justyna Zeler, Svetlana V. Eliseeva, Miguel A. Hernández-Rodríguez, Albano N. Carneiro Neto, Stéphane Petoud, Vincent Louis Pecoraro, Luís D. Carlos
nationality International
journal Chemistry – A European Journal
abstract Nanothermometry is the study of temperature at the submicron scale with a broad range of potential applications such as cellular studies or electronics. Molecular luminescent based nanothermometers offer a non‐contact means to record these temperatures with high spatial resolution and thermal sensitivity. A luminescent based molecular thermometer comprised of visible‐emitting Ga3+/Tb3+ and Ga3+/Sm3+ metallacrowns (MCs) achieved remarkable relative thermal sensitivity associated with very low temperature uncertainty of Sr = 1.9 % K‐1 and δT < 0.045 K, respectively, at 328 K, as an aqueous suspension of polystyrene nanobeads loaded with the corresponding MCs. They are so far the ratiometric molecular nanothermometers offering the highest level of sensitivity in the physiologically relevant temperature range.
publisher Wiley
year published 2020
digital object identifier (doi) 10.1002/chem.202003239
link https://doi.org/10.1002/chem.202003239