Ana Luísa Daniel da Silva
  Auxiliary Researcher  
  phone: +351 234 370 368  
  extension: 23539  
  department: Chemistry  
  office: 15.3.13  
  group: 1 - inorganic functional nanomaterials and organic-inorganic hybrids
  line: 1 - information and communication technology
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Short CV

Researcher ID:


Ana Luísa Daniel-da-Silva graduated in Chemical Engineering (2000) by Instituto Superior Técnico (Lisbon, Portugal) in 2000 and got her PhD degree in Materials Science, cum laude, from University of Alicante (Spain) in 2005. Since June 2009 she is Researcher at CICECO-Aveiro Institute of Materials and Chemistry Department of the University of Aveiro (UA). Her main scientific interests concern the development of nanostructured materials including functional nanoparticles and nanocomposites for applications in nanomedicine, bionanotechnology and water remediation. In particular, she is interested in novel strategies for surface modification with biopolymers and synthetic routes for preparing nanomaterials with innovative and enhanced properties, aiming the development of green nanosorbents and biocompatible nanomaterials. She has authored or co-authored 3 patent applications, 7 book chapters and more than 60 papers in international peer reviewed journals. In addition she has co-edited the book ‘Nanocomposite Particles for Bio-applicationsMaterials and Bio-interfaces’ (Pan Stanford, 2011). She has completed the supervision of 17 MSc theses and 17 graduation projects. At the present she (co-)supervises the scientific work of 3 Post-Doc fellows, 3 PhD students, 1 MSc student and 3 MSc researchers hired in the scope of the projects that are in progress. She has been strongly involved to several teaching activities namely by lecturing topics for post-graduation students within the subjects Nanochemistry and Frontiers of Inorganic Chemistry. As part of her academic activities she has been involved in communicating chemistry for non-specialized audiences, in particular issues related to Nanotechnology and Nanomaterials.


Academic Qualifications

 - PhD degree in Materials Science, University of Alicante (Spain), June 2005

   Thesis title: “Synthesis, characterization and adhesive properties of isocyanate ended quasi-prepolymers based adhesives”

 - BSc degree in Chemical Engineering (5 year program), IST, Lisbon (Portugal), April 2000

   Final Project title: “Production of Lignosulphonates using the residual liquor obtained in the wood pulp production (sulphite process)”


Scientific and professional activities

 -Present time: Assistant Researcher, Chemistry Department and CICECO, University of Aveiro

 -2005-2009: Postdoctoral fellow at CICECO, University of Aveiro

 -February-July 2000: Analyst at the company F. LIMA SA (Lisbon)

Scientific Interests
-Nanostructured materials
-Polymer based nanocomposites
-Materials for biomedical applications
-Colloidal nanoparticles
-Biocompatible polymers
-Drug delivery systems
R&D projects

Ongoing projects

HOTSPOT- Novel upconversion nanoparticles for multimodal therapy of melanoma: pHOtothermal Therapy, PhOtodynamic therapy and chemotherapy. 2018-2021. Coordinator-Helena Oliveira. (Member of the team)

IF/00405/2014/CP1222/ CT0007- Stimuli-responsive bionanocomposites: towards remotely controlled nanomaterials. 2015-2020. Coordinator: AL. Daniel-da-Silva

SGH-Smart Green Homes; 2016-2019 (Member of the team)

PROTEUS - Produtos e Tecnologias para o sector do Eucalyptus Globulus; 2016-2019 (Member of the team)


Past projects

PTDC/MAR-BIO/3533/2012 - Remediação de águas salinas sob a influência de multicontaminantes (poluentes inorgânicos e emergentes), através da aplicação de nanopartículas magnéticas e resíduos biológicos: avaliação do risco ecológico e humano. 2013-2015; Coordinator: Claudia B. lopes, University of Aveiro. (Member of the team)

EXPL/BBB-BEP/0317/2012 - Desenvolvimento de uma plataforma em nanoescala para o enriquecimento de proteases. 2013-2014; Coordinator: Rui Vitorino, University of Aveiro. (Member of the team)

CERN/FP/123585/2011 - Perturbed Angular Correlations and Electron Channeling Experiments at ISOLDE - applied materials research with nuclear techniques, training and development. 2012 – 2014; Coordinator - Vitor Amaral, University of Aveiro (Member of the team)

PTDC/CTM-NAN/120668/2010 - Nanomaterials for the uptake of pollutant metal ions: efficiency. selectivity and recyclability. 2012-2015; Coordinator - Tito Trindade , University of Aveiro. (Member of the team)

PTDC/SAU-TOX/120953/2010 - Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials. 2012 -2014; Coodinator - Iola Duarte , University of Aveiro. (Member of the team)

CERN/FP/116320/2010 - Perturbed Angular Correlations and Electron Channeling Experiments at ISOLDE-applied materials research with nuclear techniques, training and development; 2011 – 2012; Coordinator - Vitor Amaral, University of Aveiro. (Member of the team)

ERA-Eula/0003/2009 - Magnetotransduction: development of magnetic nanoparticle-viral vector complexes for therapeutic gene delivery in the senile brain. 2010 – 2012; Coordinator - Gerardo Goya (University of Zaragoza).(Member of the team)

CERN/FP/109357/2009 - Research on Magnetic and Multiferroic Materials using Radioactive Isotopes at ISOLDE-CERN. 2010 – 2011; Coordinator - Vitor Amaral, University of Aveiro. (Member of the team)

NANO/NMed-SD/0140/200 - Integrated Lab On Chip Platforms for Medical Diagnostics. 2009 – 2011; Coordinators - Prof. Paulo Freitas (INESC-IST); Ricardo Ibarra (University of Zaragoza). (Member of the team).

PTDC/QUI/67712/2006 - Nanochemistry of magnetic/luminescent composites for in vitro medical diagnosis applications. 2008 – 2010; Coordinator - Tito Trindade, University of Aveiro. (Member of the team)

PTDC/SAU-BEB/66896/2006 - Implantable scaffolds for local osteo-sarcoma chemotherapy. 2007 – 2010; Coodinator - Rui Correia, University of Aveiro. (Member of the team)

Scientific supervision

PhD Theses

-Maria de Almeida Vasconcelos António; SFRH/BD/136881/2018; Supervisor: AL Daniel-da-Silva; Co-supervisor: Rui Vitorino (ibimed). (2018-ongoing)

-João Tiago Moniz Fernandes; SFRH/BD/130934/2017; Supervisor: Tito Trindade; Co-supervisor: AL Daniel-da-Silva. (2017-ongoing)

-Sofia Farias Soares; SFRH/BD/121366/2016; Supervisor: AL Daniel-da-Silva; Co-supervisor: Tito Trindade. (2017-ongoing)


MSc Theses

18. Diogo Lopes, Multifunctional photocatalysts composites based on titania, Supervisors: Andrei Kavaleuski and A.L. Daniel-da-Silva (ongoing).

17. Adriana Bernardes, Liquid-phase exfoliation of highly oriented pyrolytic graphite and its oxidation by air-ozone atomization, Supervisors: Bruno Neves (Graphenest) and A.L. Daniel-da-Silva (2018).

16. Cátia Leal, Removal of AOX from paper pulp effluents using photocatalysis, Supervisors: A.L. Daniel-da-Silva and Paula Pinto (RAIZ) (2018).

15. Maria António, Detection of C-reactive protein in biological samples using functionalized gold nanoparticles, Supervisors: A.L. Daniel-da-Silva and Rui Vitorino (2017).

14. Joana Maia, Nanostructured additives for concrete, Supervisors: Frederico Maia and Cláudia Rocha (Smallmatek) and A.L. Daniel-da-Silva (2017).

13. Tiago Polónio, Treatment of the effluents of Kraft pulp industry using photocatalytic oxidation, Supervisors: António Mendes de Sousa (RAIZ) and A.L. Daniel-da-Silva (2016).

12. Tânia Silva, Study of alternative resins in decorative paints, Supervisors: Vasco Lopes (CIN) and A.L. Daniel-da-Silva (2015).

11. Ana Raquel Fernandes, Laccase immobilization onto magnetic nanoparticles: study and applications, Supervisors: A. Xavier and A.L. Daniel-da-Silva (2015).

10. Tânia Simões, Magnetic removal of pollutants from water using green nanocomposites, Supervisors: A.L. Daniel-da-Silva and T. Trindade (2015).

9. Marta Julia Busse, Bionanocomposites of Fe3O4/SiO2 and alginate for the magnetic removal of Cr(III) species in water, Supervisors: T. Trindade and A.L. Daniel-da-Silva (2014).

8. Catarina Rebelo, Gold nanocomposites for controlled drug release, Supervisor: A.L. Daniel-da-Silva (2014).

7. Bianca Creaney, Nano-adsorventes para remoção magnética de corantes orgânicos de águas, Supervisors: A.L. Daniel-da-Silva (2013).

6. Maria Graça Oliveira, Hidrogéis nanocompósitos de ouro para aplicações em libertação controlada de fármacos, Supervisors: A.L. Daniel-da-Silva (2012).

5. Luís Melo, Libertação de prata ionica em nanocompositos, Supervisors: Tito Trindade and A.L. Daniel-da-Silva (2012).

4. Rui Pedro Silva, Funcionalização de nanopartículas magnéticas para o desenvolvimento de um sistema de caraterização de proteases, Supervisors: Rui Vitorino and A.L. Daniel-da-Silva (2012).

3. Ana Margarida Salgueiro, Hidrogeis termosensiveis compósitos contendo nanobastonetes de ouro, Supervisors: A. L. Daniel-da-Silva and Tito Trindade (2011).

2. Cristina Schitco, Thermo conductivity and electrical properties of PVDF/Cu nanocomposites, Supervisors: Paula Vilarinho and A.L. Daniel-da-Silva (2011).

1. Joana da Silva Moreira, Estudo de síntese e cinética de libertação em bionanocompósitos, Supervisors: Tito Trindade and  A.L. Daniel-da-Silva (2010).

Selected Publications

SCI papers

1. A.M. Salgueiro, A.L. Daniel-da-Silva, A.V. Girão, P.C. Pinheiro, T. Trindade, Unusual dye adsorption behavior of k-carrageenan coated superparamagnetic nanoparticles, Chemical Engineering Journal, 2013, 229, 276-284.

2. A. C. Estrada, A. L. Daniel-da-Silva, T. Trindade, Photothermally enhanced drug release by k-carrageenan hydrogels reinforced with multiwalled carbon nanotubes, RSC Advances 2013, 3, 10828-10836.

3. D. S. Tavares, A. L. Daniel-da-Silva, C. B. Lopes, N. J. O. Silva, V. S. Amaral, J. Rocha, E. Pereira, T. Trindade, Efficient sorbents based on magnetite coated with siliceous hybrid shells for removal of mercury ions, Journal Materials Chemistry A 2013, 1, 8134-8143.

4. A. L. Daniel-da-Silva, R. S. Carvalho, T Trindade, Magnetic Hydrogel Nanocomposites and Composite Nanoparticles – a Review of Recent Patented Works, Recent Patents on Nanotechnology 2013, 7, 153 – 166.

5. A.M. Salgueiro, A.L. Daniel-da-Silva, S. Fateixa,T. Trindade, k-carrageenan hydrogel nanocomposites with release behavior mediated by morphological distinct Au nanofillers, Carbohydrate Polymers 2013, 91, 100-109.

6. J.F. B. Barata, A.L. Daniel-da-Silva, M.G.P.M.S. Neves, J.A.S. Cavaleiro, T.Trindade. Corrole-silica hybrid particles: synthesis and effects on singlet oxygen generation, RSC Advances 2013, 3, 274-280.

7. A.L. Daniel-da-Silva, A.M. Salgueiro, T. Trindade, Effects of Au nanoparticles on thermoresponsive genipin-crosslinked gelatin hydrogels, Gold Bulletin 2013, 46, 25-33.

8. A.L. Daniel-da-Silva; J. Moreira; R. Neto; A.C. Estrada; A.M. Gil; T. Trindade, Impact of magnetic nanofillers in the swelling and release properties of k-carrageenan hydrogel nanocomposites, Carbohydrate Polymers 2012, 87, 328-335.

9. J.A. Ferreira; A.L. Daniel-da-Silva; R.M.P. Alves; D.S. Duarte; I. Vieira; R. Ferreira; L. Lara Santos; R. Vitorino; F. Amado, Synthesis and optimization of lectin functionalized nanoprobes for the selective recovery of glycoproteins from human body fluids, Analytical Chemistry 2011, 83, 7035-7043.

10. A.L. Daniel-da-Silva; L. Ferreira; A.M. Gil; T. Trindade, Synthesis and swelling behavior of temperature responsive k-carrageenan nanogels, Journal of Colloid and Interface Science 2011, 355, 512-517.

11. N. Barroca; P. M. Vilarinho; A.L. Daniel-da-Silva; A. Wu; M.H.V. Fernandes; A. Gruverman. Protein Adsorption on Piezoelectric Poly (L-lactic) acid thin films by scanning probe microscopy. Applied Physics Letters 2011, 98, 133705.

12. K.B. Sidhpuria; A.L. Daniel-da-Silva; T. Trindade; J.A.P. Coutinho, Supported ionic liquid silica nanoparticles (SILnPs) as an efficient and recyclable heterogeneous catalyst for the dehydration of fructose to 5-hydroxymethylfurfural, Green Chemistry 2011, 13, 340-349.

13. N.B. Barroca; A.L. Daniel-da-Silva; P.M. Vilarinho; M.H.V. Fernandes, Tailoring the morphology of high molecular weight PLLA scaffolds through bioglass additions, Acta Biomaterialia 2010, 6, 3611-3620.

14. P.I. Girginova; A.L. Daniel-da-Silva; C. Lopes; P. Figueira; M. Ortero; V.S. Amaral; E. Pereira; T. Trindade , Silica coated magnetite nanoparticles for magnetic removal of Hg2+ from water, Journal of Colloid and Interface Science 2010, 345, 234-240.

15. A.L. Daniel-da-Silva; S. Fateixa; A.J. Guiomar; B.F.O. Costa; N.J.O. Silva; T. Trindade; B.J. Goodfellow; A.M. Gil, Biofunctionalized magnetic hydrogel nanospheres of magnetite and kappa-carrageenan, Nanotechnology 2009, 20, 355602, 1-10.

16. A.L. Daniel-da-Silva; R. Lóio; J.A. Lopes-da-Silva; T. Trindade; B.J. Goodfellow; A.M. Gil, Effects of magnetite nanoparticles on the thermo-rheological properties of carrageenan hydrogels, Journal of Colloid and Interface Science 2008, 324, 205-211.

17. A.L. Daniel-da-Silva; T. Trindade; B.J. Goodfellow; B.F.O. Costa; R.N. Correia; A.M. Gil, In situ synthesis of magnetite nanoparticles in carrageenan gels, Biomacromolecules 2007, 8(8), 2350-2357.

18. A.L. Daniel-da-Silva; A.B. Lopes; A.M. Gil; R.N. Correia, Synthesis and characterization of porous k-carrageenan/calcium phosphate nanocomposites scaffolds, Journal of Materials Science 2007, 42(20), 8581-8591.

19. A.L.D. da Silva; J.C.M. Bordado; J.M. Martín-Martínez, Influence of the free isocyanate content in the adhesive properties of reactive trifunctional polyether urethane quasi-prepolymers, International Journal of Adhesion and Adhesives 2006, 26(5), 355-362.

20. A.L. Silva; J.C. Bordado, Recent Developments in Polyurethane Catalysis: Catalytic Mechanisms Review Catalysis Reviews. Science and Engineering 2004, 46-1, 31-51.

Book chapters

1. A.L. Daniel-da-Silva; T.Trindade, Biofunctional composites of polysaccharides containing inorganic nanoparticles, In. Advances in Nanocomposite technology,  Intech – Open Access Publisher, 2011, ISBN: 978-953-308-55-0.

2. A.S. Pereira; A.L. Daniel-da-Silva; T.Trindade, From nanoparticles to nanocomposites: an Overview, In. Nanocomposite particles for bio-applications– materials and biointerfaces, Chapt. 1, Pan Stanford Publishing, 2011, ISBN: 978-981-4267-78-6.

3. A.L. Daniel-da-Silva; N. J. O. Silva; T. Trindade; A. M. Gil, Biocomposites containing magnetic nanoparticles, In. Nanocomposite particles for bio-applications– materials and biointerfaces, Chapt. 8, Pan Stanford Publishing, 2011, ISBN: 978-981-4267-78-6.


Patente de Invenção Nacional nº 104136, 22-01-2010
Mª Helena Fernandes, Paula Mª Vilarinho, Ana Luísa Silva; Natália Barroca
Método de preparação de suportes porosos compósitos de base polimérica para aplicação em engenharia de tecidos


Books (editor)

T. Trindade; A. L. Daniel-da-Silva (Eds), Nanocomposite particles for bio-applications – materials and biointerfaces, Pan Stanford Publishing, 2011, ISBN: 978-981-4267-78-6

Reviewing and evaluation activities

Referee of SCI journals

ACS Applied Materials & Interfaces, ACS Applied Nano Materials, ACS Omega, Biomacromolecules, Biomaterials, Carbohydrate Polymers, Industrial & Engineering Chemistry Research, International Journal of Biological Macromolecules, Journal of Colloid and Interface Science, Journal of Physics and Chemistry of Solids, Nanotechnology, NPG Asia Materials, RSC Advances, Separation and Purification Technology, Water Science and Technology

Verified Peer Review Record at the Publons Platform:


Evaluation of projects/proposals

- ANI (Agência Nacional de Inovação, Portugal)

ongoing scientific supervisions