João Mano
  Full professor  
  phone: 234370733  
  extension: 33568  
  department: Chemistry  
  office: 29.1.27  
  group: 5 - biomedical and biomimetic materials
  direct url:  
Short CV

João F. Mano (CEng, PhD, DSc) is a full professor at the Department of Chemistry of the University of Aveiro (Portugal). During his career he has been teaching courses related to biomaterials science and technology, tissue engineering and physical-chemistry of polymers and materials, in both undergraduate and graduate levels. He published three educational-related papers in peer-reviewed international journals and was involved in several training/educational activities.

His current research interests include the use of biomaterials and cells towards the development of transdisciplinary concepts especially aimed at being used in regenerative/personalised medicine. In particular, biomimetic and nano/micro-technology approaches have been applied to natural-derived biomaterials and surfaces in order to obtain biomedical devices with improved structural and functional (including bio-instructive) properties, or in the engineering of microenvironments to control cell behaviour and organization, to be used in therapies or in drug screening.

João F. Mano is author of 630+ SCI works (14000+ citations, h=59, including 520+ original research or review papers), about 40 book chapters, 500+ communications in international conferences and three patents as senior inventor. João F. Mano co-edited 5 special issues in international journals and three books. João F. Mano has been invited to review manuscripts from 200+ different international journals and to routinely evaluate projects from numerous private and state funding agencies from different countries. João F. Mano supervised or co-supervised 37 MSc, 17 PhD students, and 20+ post-doctoral fellows. He has been part of a series of scientific societies and editorial boards of international journals, including Tissue Engineering (parts A, B and C), Advanced Healthcare Materials, Advanced Engineering Materials, Materials Letters, Polymers, Materials Today Chemistry, and Journal of Bioactive and Compatible Polymers. He has been coordinating or involved in many national and European research projects and participated in the organization of scientific events in the area of polymer/materials science and biomaterials/tissue engineering.

João F. Mano has been member of scientific committees, organizing committees, referee and chairman in different international meetings. He was invited to present 60+ invited/keynote/plenary talks in international conferences including EUROMAT, ESTAC, TERMIS (EU and AP chapters and World conference), BIOMED, FBPS, NANOMED, COLAOB, ESB, SFB, World Biomaterials Conference, E-MRS or ESAO.

João F. Mano has received different honours and awards: (i) fellow of the IUPAC (International Union of Pure and Applied Chemistry) since 2004; (ii) the Stimulus to Excellence Award by the Portuguese Minister for Science and Technology in 2005; (iii) the Materials Science and Technology Prize, attributed by the Federation of European Materials Societies (FEMS) in 2007 (iv) UNESCO Chair on Biomaterials attributed in 2008 from the University of Havana (Cuba); (v) the major BES innovation award in 2010 (at that time, one of the most recognised innovation prize in Portugal); (vi) recipient an Advanced Grant from the European Research Council (ERC-AdG), in 2015.


◊ Habilitation in Tissue Engineering, Regenerative Medicine and Stem Cells (Univ. of Minho) - 2012

◊ PhD in Chemistry (Technical University of Lisbon) - 1996

◊ Chemical Engineering degree (I.S.T.) - 1992.

Research Area

◊ Chemical modification, processing, and surface modification of biomacromolecular-based systems for biomedical applications, including tissue engineering devices and systems for controlled delivery of molecules.

◊ Smart (stimuli responsive / bioinstructive) and bioactive biomaterials/nanomaterials.

◊ Biomimetic approaches in tissue engineering.

◊ Nanobiotechnology.

◊ Stem Cells-materials interactions.

Representative Publications (last 5 years)

AI Neto, CA Custódio, WL Song, JF Mano – High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates. Soft Matter, 7, 4147 (2011).

CR Correia, RL Reis, JF Mano - Multilayered hierarchical capsules providing cell adhesion sites.  Biomacromolecules, 14, 743 (2013).

RR Costa, E Castro, FJ Arias, JC Rodríguez-Cabello, JF Mano - Multifunctional Compartmentalized Capsules with a Hierarchical Organization from the Nano to the Macro Scales. Biomacromolecules, 14, 2403 (2013).

AC Lima, CA Custódio, C Alvarez-Lorenzo, JF Mano - Biomimetic methodology to produce polymeric multilayered particles for biotechnological and biomedical applications. Small, 9, 2487 (2013).

AI Neto, CR Correia, CA Custodio, JF Mano - Biomimetic miniaturized platform able to sustain arrays of liquid droplets for high-throughput combinatorial tests. Adv Funct Mater 24, 5096 (2014).

J.M. Silva, A.R.C. Duarte, S.G. Caridade, C. Picart, R.L. Reis, J.F. Mano - Tailored freestanding multilayered membranes based on chitosan and alginate. Biomacromolecules, 15(10), 3817–3826 (2014)

J Borges, JF Mano - Molecular interactions driving the layer-by-layer assembly of multilayers. Chem Rev, 114, 8883 (2014)

C.A. Custódio, M.T. Cerqueira, A.P. Marques, R.L. Reis, J.F. Mano - Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration. Biomaterials, 43, 23–31 (2015)

A.M.S. Costa, J.F. Mano - Highly robust hydrogels via a fast, simple and cytocompatible dual crosslinking-based process. Chemical Communications, 51, 15673-15676 (2015)

C.R. Correia, R.P. Pirraco, M.T. Cerqueira, A.P. Marques, R.L. Reis, J.F. Mano - Semipermeable capsules wrapping a multifunctional and self-regulated co-culture microenvironment for osteogenic differentiation. Scientific Repports, 6, 21883 (2016)

M.J. Cardoso, S.G. Caridade, R.R. Costa, J.F. Mano - Enzymatic degradation of polysaccharide-based layer-by-layer structures. Biomacromolecules, 17, 1347–1357 (2016)

A.I. Neto, N.L. Vasconcelos, S.M. Oliveira, D. Ruiz-Molina, J.F. Mano - High-throughput topographic, mechanical, and biological screening of multilayer films containing mussel-inspired biopolymers. Advanced Functional Materials, 26, 2745–2755 (2016)

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