TISSUE REACTOR - Development of a Bioreactor-Based Connective Tissue Production Line
funding type European Comission
programme FP5-GROWTH
acronym/
reference
TISSUE REACTOR
alternative reference G5RD-CT-2000-00282
research group(s) 5 - biomedical and biomimetic materials;
department Materials and Ceramic Engineering (DEMaC)
execution dates 2001-02-01 - 2004-01-31 ( 36 Months )
project extension date 2005-02-01 ( 12 Extra months )
abstract/
keywords
It is the aim of this project to engineer connective tissue in vitro and to demonstrate its applicability as a tissue substitute in vivo. To achieve this goal a continuous cultivation process based on a perfused fixed-bed bioreactor system and its components will be developed which allows the production of large quantities of three-dimensional (3-d) tissue cultures in combination with capillary-like prevascular precursors to form in vitro tissue constructs. The primary focus will be bone tissue, and bone tissue constructs will then subsequently be implanted in vivo to demonstrate their potential to improve current limitations in bone substitution surgery.
coordinator
/local pi
Maria Margarida Tavares Lopes Almeida
ciceco status Partner
proponent institution University of Ulm<br />Germany
partner institution(s) BIOSCAN B.V.
Netherlands
CAM IMPLANTS B.V.
Netherlands
GBF - NATIONAL CENTRE FOR BIOTECHNOLOGY
Germany
MEREDOS GMBH
Germany
MNEMOSCIENCE GMBH
Germany
UNIVERSITY OF AVEIRO
Portugal
UNIVERSITY OF MANCHESTER
United Kingdom
UNIVERSITY OF NOTTINGHAM
United Kingdom
industrial partner(s) yes
international partner(s) yes
total budget 2.881.000€
ciceco budget 233.600€
project code 3.50.62
link http://cordis.europa.eu/project/rcn/54250_en.html
publications
Sponsors

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