Carla Vilela has a graduation in Chemical Engineering (2004), master in Materials Science and Engineering (2008) and PhD in Chemistry (2012) by the University of Aveiro (UA, Portugal). During 4 years (2004-2008), she was a laboratory technician responsible for the laboratory management and organization, as well as for the technical and laboratorial support to graduation and post-graduation students and R&D projects at UA. Between 2009 and 2011 she was a volunteer assistant lecturer of the laboratory classes of Elements of Physical Chemistry and General Chemistry in the Chemistry Department of the same university. In 2013, she started a post-doctoral project (FCT grant) at CICECO–Aveiro Institute of Materials.
Currently, she is a researcher at the same institute and her main research interests include the sustainable use of biopolymers for the development of novel functional nanostructured materials for both biomedical and technological applications. She is the author/co-author of 1 book, 3 book chapters, 43 articles in international peer reviewed multidisciplinary high impact journals (ISI, h-index 18, citations: 1111), and several oral and poster communications in national and international conferences. CVilela is a member of the Portuguese Materials Society (SPM), European Polysaccharide Network of Excellence (EPNOE) and Editorial Board of Cogent Chemistry (Taylor & Francis).
twitter.com/CarlaACVilela
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Her research interests focus on the sustainable use of biopolymers (bacterial cellulose, chitosan, alginate, pullulan, proteins, etc.) for the engineering of multifunctional materials for both biomedical (e.g. drug delivery) and technological (e.g. active packaging and fuel cells) applications.
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Portuguese Collaborators
- CICECO, UA: Carmen S.R. Freire, Armando J.D. Silvestre, Filipe M.L. Figueiredo, Paulo R. Claro, Mariela Nolasco
- TEMA, UA: Gil Gonçalves, Eddy M. Domingues
- CESAM, UA: Helena Oliveira, Adelaide Almeida
International Collaborators
- The Hebrew University of Jerusalem, Israel: Zvi Hayouda
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National projects
- National project 034/7.1/ADI/NOR (2008, TEAM MEMBER): Synthesis of resins from fatty acids / vegetable oils.
- National project PTDC/QUI-QUI/120982/2010 (2013, TEAM MEMBER): Creating value from bio-wastes: suberin extraction and biotransformation in biocompatible ionic liquids aiming on novel biomaterials and compounds .
- National project CENTRO-01-0145-FEDER-031289 (2018-2021, TEAM MEMBER): NANOBIOINKS – Engineering bio-based nanofibers for the development of high-performance nanostructured bioinks for 3-D bioprinting (in progress).
European projects
- European Project SUSTAINPACK IP-500311-2 (2004-2008, TEAM MEMBER): Innovation and Sustainable Development in the Fibre-based Packaging Value Chain.
- European project H2020-BBI-JTI-201 ID:8837527 (2019-2023, TEAM MEMBER): GRETE - Green chemicals and technologies for the wood-to-textile value chain (in progress).
ISIS Neutron and Muon Source, Rutherford Appleton Laboratory (RAL, Oxford, UK)
- Beamtime at TOSCA instrument, experiment number: 1820360 (November 16-20, 2018, TEAM MEMBER): Structural characterization of cellulose-based nanocomposites by inelastic neutron scattering.
- Beamtime at TOSCA instrument, experiment number: 1920244 (November 13-18, 2019, TEAM MEMBER): API-DES: improving drug solubility with deep eutectic solvents by inelastic neutron scattering.
COST Actions
- Participation in the COST Action FP1405: Active and intelligent fibre-based packaging – innovation and market introduction (ActInPak, http://www.actinpak.eu/) (2015-2019).
- Participation in the COST Action CA18220: European network of FURan based chemicals and materials FOR a Sustainable development (2019-2023, in progress).
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PhD students
Ana C.Q. Silva, Development of micromotors based on cellulose via microfluidics for drug delivery and diagnosis, Doctoral Programme in Biochemistry, Supervisors: Doctor Carmen S.R. Freire, Professor Armando J.D. Silvestre and Doctor Carla Vilela, FCT grant: SFRH/BD/140230/2018, University of Aveiro, 2018/2022 (in progress).
Bruno F.A. Valente, Development of thermoplastic composites with high cellulose incorporation, Doctoral Programme in Biorefinery, Supervisors: Doctor Carmen S.R. Freire, Doctor Carla Vilela and Professor Carlos Pascoal Neto, Project grant: BD INPACTUS/BR18/UA/09-01/2018, University of Aveiro, 2018/2022 (in progress).
Maria C. Teixeira, Development of bioinks based on biopolymers for 3D bioprinting, Doctoral Program in Nanosciences and Nanotechnology, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2019/2023 (in progress).
MSc students
Louise Saïdi, Bacterial cellulose/poly(N-methacryloyl glycine) nanocomposites by in situ polymerization, Master in Functionalized Advanced Materials and Engineering (Erasmus Mundus FAME), Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2014/2015.
Ana P. Martins, Bacterial cellulose based composite membranes for fuel cells, Master in Chemical Engineering, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2015/2016.
Daniel M. Cordeiro, Development of nanocellulose-based membranes for microbial fuel cells, Master in Biotechnology, Supervisors: Doctor Carla Vilela and Doctor Carmen S.R. Freire, University of Aveiro, 2016/2017.
Marta F.G. Maia, Development of multilayer systems for the controlled delivery of anti-cancer drugs, Master in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2016/2017.
João P.F. Carvalho, Multi-layered nanosystems for the controlled release of anticancer drugs, Master in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2017/2018.
Barbara Pereira, New microneedle systems for transdermal delivery, Master in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2018/2019.
João Morais, Biomembranes based on bacterial nanocellulose for polymer electrolyte fuel cells, Master in Chemical Engineering, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2018/2019.
Cristiana Gonçalves, Development of microneedle systems for melanoma treatment, Master in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2019/2020 (in progress).
João Leite, Multifunctional cellulose nanoparticles for application in diagnosis and cancer therapy, Master in Biomedical Materials and Devices, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2019/2020 (in progress).
BSc students (graduation final project)
Júlia C.S. Matos, New biocompatible and bioactive materials from bacterial cellulose, Graduation in Biotechnology, Supervisors: Professor Armando J.D. Silvestre and Doctor Carla Vilela, University of Aveiro, 2012/2013.
Ana P.D. Amorim, Novel nanocellulose composites for biomedical applications, Graduation in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2014/2015.
Cristina A.M. Silva, Novel bacterial cellulose nanocomposites for application in biomineralization, Graduation in Biotechnology, Supervisors: Doctor Carla Vilela and Doctor Carmen S.R. Freire, University of Aveiro, 2015/2016.
Cátia F.M. Rodrigues, Development of multilayer membranes for drug delivery, Graduation in Biochemistry, Supervisors: Doctor Carla Vilela and Doctor Carmen S.R. Freire, University of Aveiro, 2016/2017.
Catarina P. Rodrigues, Development of implantable materials for cardiac regeneration, Graduation in Biochemistry, Supervisors: Doctor Carmen S.R. Freire and Doctor Carla Vilela, University of Aveiro, 2017/2018.
Ana M.S. Loureiro, Design of multilayer capsules for the controlled delivery of anti-cancer drugs, Graduation in Biochemistry, Supervisors: Doctor Carla Vilela and Doctor Carmen S.R. Freire, University of Aveiro, 2017/2018.
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Physicochemical surface properties of bacterial cellulose/polymethacrylate nanocomposites: an approach by inverse gas chromatographyFaria, M; Vilela, C; Silvestre, AJD; Deepa, B; Resnik, M; Freire, CSR; Cordeiro, N 2019, CARBOHYDRATE POLYMERS, 206, 86-93.
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Poly(glycidyl methacrylate)/bacterial cellulose nanocomposites: Preparation, characterization and post-modificationFaria, M; Vilela, C; Mohammadkazemi, F; Silvestre, AJD; Freire, CSR; Cordeiro, N 2019, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 127, 618-627.
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Exploiting poly(e-caprolactone) and cellulose nanofibrils modified with latex nanoparticles for the development of biodegradable nanocompositesVilela, C; Engstrom, J; Valente, BFA; Jawerth, M; Carlmark, A; Freire, CSR 2019, POLYMER COMPOSITES, 40, 4, 1342-1353.
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Nanocellulose-based antifungal nanocomposites against the polymorphic fungus Candida albicansVilela, C; Oliveira, H; Almeida, A; Silvestre, AJD; Freire, CSR 2019, CARBOHYDRATE POLYMERS, 217, 207-216.
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Zwitterionic Nanocellulose-Based Membranes for Organic Dye RemovalVilela, C; Moreirinha, C; Almeida, A; Silvestre, AJD; Freire, CSR 2019, MATERIALS, 12, 9,
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A compendium of current developments on polysaccharide and protein-based microneedlesDaniela F.S. Fonseca, Carla Vilela, Armando J.D. Silvestre, Carmen S.R. Freire 2019, International Journal of Biological Macromolecules, 136, 704-728.
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Antimicrobial and Conductive Nanocellulose-Based Films for Active and Intelligent Food PackagingCarla Vilela, Catarina Moreirinha, Eddy M. Domingues, Filipe M. L. Figueiredo, Adelaide Almeida, Carmen S. R. Freire 2019, Nanomaterials, 9, 7,
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Synthesis and characterization of photoactive porphyrin and poly(2-hydroxyethyl methacrylate) based materials with bactericidal propertiesKelly A.D.F. Castro, Nuno M.M. Moura, Mário M.Q. Simões, José A.S. Cavaleiro, Maria do Amparo F. Faustino, Ângela Cunha, Filipe A. Almeida Paz, Ricardo F. Mendes, Adelaide Almeida, Carmen S.R. Freire, Carla Vilela, Armando J.D. Silvestre, Shirley Nakagaki, Maria da Graça P.M.S. Neves 2019, Applied Materials Today, 16, 332-341.
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Pullulan-based nanocomposite films for functional food packaging: Exploiting lysozyme nanofibers as antibacterial and antioxidant reinforcing additivesSilva, NHCS; Vilela, C; Almeida, A; Marrucho, IM; Freire, CSR 2018, FOOD HYDROCOLLOIDS, 77, 921-930.
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Tuning lysozyme nanofibers dimensions using deep eutectic solvents for improved reinforcement abilitySilva, NHCS; Vilela, C; Pinto, RJB; Martins, MA; Marrucho, IM; Freire, CSR 2018, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 115, 518-527.
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Poly(bis[2-(methacryloyloxy)ethyl]phosphate)/Bacterial Cellulose Nanocomposites: Preparation, Characterization and Application as Polymer Electrolyte MembranesVilela, C; Martins, APC; Sousa, N; Silvestre, AJD; Figueiredo, FML; Freire, CSR 2018, APPLIED SCIENCES-BASEL, 8, 7,
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A concise guide to active agents for active food packagingVilela, C; Kurek, M; Hayouka, Z; Rocker, B; Yildirim, S; Antunes, MDC; Nilsen-Nygaard, J; Pettersen, MK; Freire, CSR 2018, TRENDS IN FOOD SCIENCE & TECHNOLOGY, 80, 212-222.
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Secondary metabolites from Eucalyptus grandis wood cultivated in Portugal, Brazil and South AfricaSantos, SAO; Vilela, C; Domingues, RMA; Oliveira, CSD; Villaverde, JJ; Freire, CSR; Neto, CP; Silvestre, AJD 2017, INDUSTRIAL CROPS AND PRODUCTS, 95, 357-364.
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Multilayered materials based on biopolymers as drug delivery systemsVilela, C; Figueiredo, ARP; Silvestre, AJD; Freire, CSR 2017, EXPERT OPINION ON DRUG DELIVERY, 14, 2, 189-200.
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Protonic conductivity and fuel cell tests of nanocomposite membranes based on bacterial celluloseGadim, TDO; Loureiro, FJA; Vilela, C; Rosero-Navarro, N; Silvestre, AJD; Freire, CSR; Figueiredo, FML 2017, ELECTROCHIMICA ACTA, 233, 52-61.
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Development and applications of cellulose nanofibres based polymer nanocompositesCarla Vilela, Ricardo J. B. Pinto, Ana R. P. Figueiredo, Carlos Pascoal Neto, Armando J. D. Silvestre, Carmen S. R. Freire In Ehsan Bafekrpour (Eds.), Advanced Composite Materials: Properties and Applications 2017, 1-65. Warsaw/Berlin: De Gruyter Open.
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Polyethylene Terephthalate: Copolyesters, Composites, and Renewable AlternativesAndreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho In P. M. Visakh Mong Liang (Eds.), Poly(ethylene Terephthalate) Based Blends, Composites and Nanocomposites. 2015, 111-139. Elsevier Science Ltd.
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2 Bacterial Cellulose-Based Nanocomposites: Roadmap for Innovative MaterialsA. R. P. Figueiredo, C. Vilela, C. Pascoal Neto, A.J.D. Silvestre and C.S.R. Freire Nanocellulose Polymer Nanocomposites: Fundamentals and Applications 2014, Scrivener: Willey.
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Novel multilayered nanostructured drug delivery systems obtained by layer-by-layer assembly of cellulose nanocrystals Maia. M, Vilela. C, Pinto. R, Valente. B, Carvalho. T, Freire. C 2018,
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Biosorbent films based on nanocellulose and lysozyme nanofibers for efficient removal of mercury (II) from natural watersSilva, N; Figueira, P; Vilela, C; Pinto, R; Marrucho, I; Periera, M; Freire, C 2018, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 255,
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Cellulose nanofibrils modified with latex nanoparticles as reinforcement for biodegradable poly(ε-caprolactone)-based compositesC. Vilela, J. Engström, B.F.A. Valente, M. Jawerth, A. Carlmark, C.S.R. Freire
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Biosorbent films based on nanocellulose and lysozyme nanofibers for efficient removal of mercury (II) from natural watersSilva, N; Figueira, P; Vilela, C; Pinto, R; Marrucho, I; Pereira, M; Freire, C 2018, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 255,
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