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education & academic carreer:
- PhD student in the Doctoral Programme in Health Sciences and Technology, funded by the FCT (grant SFRH/BD/87520/2012).
- Researcher under project PTDC/QUI-QUI/101022/2008 from FCT (March 2012 - February 2013).
- MSc in Pharmaceutical Biomedicine, University of Aveiro, Portugal 2011, with the MSc thesis 'Molecular modelling of transmembranar transporters for chloride'.
- Graduated in Biomedical Sciences, Pharmaceutical minor, University of Aveiro, Portugal 2009.
find me also in...
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Development of a Library of Thiophene-Based Drug-Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and CytotoxicityVieira, P; Miranda, MQ; Marques, I; Carvalho, S; Chen, LJ; Howe, ENW; Zhen, C; Leung, CY; Spooner, MJ; Morgado, B; Silva, OABDE; Moiteiro, C; Gale, PA; Felix, V
2020, CHEMISTRY-A EUROPEAN JOURNAL, 26, 4, 888-899.
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Lipidomic analysis of human primary hepatocytes following LXR activation with GW3965 identifies AGXT2L1 as a main target associated to changes in phosphatidylethanolamineSantinha, D; Klopot, A; Marques, I; Ellis, E; Jorns, C; Johansson, H; Melo, T; Antonson, P; Jakobsson, T; Felix, V; Gustafsson, JA; Domingues, MR; Mode, A; Helguero, LA
2020, JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 198,
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The Green Box: An Electronically Versatile Perylene Diimide Macrocyclic Host for FullerenesBarendt, TA; Myers, WK; Cornes, SP; Lebedeva, MA; Porfyrakis, K; Marques, I; Felix, V; Beer, PD
2020, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142, 01-Jan, 349-364.
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Anion Recognition in Water by Charge-Neutral Halogen and Chalcogen Bonding Foldamer ReceptorsBorissov, A; Marques, I; Lim, JYC; Felix, V; Smith, MD; Beer, PD
2019, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 141, 9, 4119-4129.
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Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transportSpooner, MJ; Li, HY; Marques, I; Costa, PMR; Wu, X; Howe, ENW; Busschaert, N; Moore, SJ; Light, ME; Sheppard, DN; Felix, V; Gale, PA
2019, CHEMICAL SCIENCE, 10, 7, 1976-1985.
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A Chiral Halogen-Bonding [3]Rotaxane for the Recognition and Sensing of Biologically Relevant Dicarboxylate AnionsLim, JYC; Marques, I; Felix, V; Beer, PD
2018, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 57, 2, 584-588.
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Chiral halogen and chalcogen bonding receptors for discrimination of stereo- and geometric dicarboxylate isomers in aqueous mediaLim, JYC; Marques, I; Felix, V; Beer, PD
2018, CHEMICAL COMMUNICATIONS, 54, 77, 10851-10854.
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Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigationsMarques, I; Costa, PMR; Miranda, MQ; Busschaert, N; Howe, ENW; Clarke, HJ; Haynes, CJE; Kirby, IL; Rodilla, AM; Perez-Tomas, R; Gale, PA; Felix, V
2018, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 20, 32, 20796-20811.
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A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrationsBusschaert, N; Park, SH; Baek, KH; Choi, YP; Park, J; Howe, ENW; Hiscock, JR; Karagiannidis, LE; Marques, I; Felix, V; Namkung, W; Sessler, JL; Gale, PA; Shin, I
2017, NATURE CHEMISTRY, 9, 7, 667-675.
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Enantioselective Anion Recognition by Chiral Halogen-Bonding [2]Rotaxa nesLim, JYC; Marques, I; Felix, V; Beer, PD
2017, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, 35, 12228-12239.
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Chalcogen Bonding Macrocycles and [2]Rotaxanes for Anion RecognitionLim, JYC; Marques, I; Thompson, AL; Christensen, KE; Felix, V; Beer, PD
2017, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, 8, 3122-3133.
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Anion- and Solvent-Induced Rotary Dynamics and Sensing in a Perylene Diimide [3]CatenaneBarendt, TA; Ferreira, L; Marques, I; Felix, V; Beer, PD
2017, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, 26, 9026-9037.
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Iodide Recognition and Sensing in Water by a Halogen-Bonding Ruthenium(II)-Based RotaxaneLangton, MJ; Marques, I; Robinson, SW; Felix, V; Beer, PD
2016, CHEMISTRY-A EUROPEAN JOURNAL, 22, 1, 185-192.
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Enhancing the enantioselective recognition and sensing of chiral anions by halogen bondingLim, JYC; Marques, I; Ferreira, L; Felix, V; Beer, PD
2016, CHEMICAL COMMUNICATIONS, 52, 32, 5527-5530.
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Selective Nitrate Recognition by a Halogen-Bonding Four-Station [3]Rotaxane Molecular ShuttleBarendt, TA; Docker, A; Marques, I; Felix, V; Beer, PD
2016, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55, 37, 11069-11076.
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Vítor Félix and Igor Marques article on Nature Chemistry cover
