Tânia E. Sintra got her MSc degree in Pharmaceutical Sciences at University of Coimbra in 2011. By the middle of 2017 she completed her PhD in Chemistry by University of Aveiro, having during her PhD studies trainee at Faculty of Engineering of the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany. Since then, she is a post-doctoral researcher at CICECO-Aveiro Institute of Materials, University of Aveiro, under the scope of the R&D project SusPhotoSolutions. In 2018, she was awarder with a R&D project (Chiral resolution of drugs in centrifugal partition chromatography using enantioselective aqueous biphasic systems, ChiResus), from the Portuguese Foundation for Science and Technology (FCT), where she is the Principal Investigator (PI). Her last 6 years were dedicated to research on Chemistry and Pharmaceutical areas with focus on organic and analytical chemistry. During her scientific path she have contributed to the development of innovative research in the synthesis of benign ionic liquids to respond to major challenges of pharmaceutical industry, namely the separation of two enantiomers and the lack of aqueous solubility of some promising drugs. Since 2012, Tânia E. Sintra published 21 articles in international peer reviewed scientific journals, with more than 370 citation and an h-index of 10 (data obtained from Scopus at 17th February 2019), and presented several oral and poster communications in national and international conferences.
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2013 - 2017 | PhD in Chemistry | University of Aveiro,Thesis title "Synthesis of more benign ionic liquids for specific applications", supervised by Prof. Dr. João A.P. Coutinho (UA) and co-supervised by Prof. Dr. Sónia P.M. Ventura (UA).
2006 - 2011 | PharmD in Pharmaceutical Sciences | University of Coimbra
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Anti-inflammatory and antioxidant nanostructured cellulose membranes loaded with phenolic-based ionic liquids for cutaneous applicationMorais, ES; Silva, NHCS; Sintra, TE; Santos, SAO; Neves, BM; Almeida, IF; Costa, PC; Correia-Sa, I; Ventura, SPM; Silvestre, AJD; Freire, MG; Freire, CSR 2019, CARBOHYDRATE POLYMERS, 206, 187-197.
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Synthesis and characterization of analogues of glycine-betaine ionic liquids and their use in the formation of aqueous biphasic systemsPereira, MM; Pedro, SN; Gomes, J; Sintra, TE; Ventura, SPM; Coutinho, JAP; Freire, MG; Mohamadou, A 2019, FLUID PHASE EQUILIBRIA, 494, 239-245.
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Synthesis and characterization of chiral ionic liquids based on quinine, L-proline and L-valine for enantiomeric recognitionSintra, TE; Gantman, MG; Ventura, SPM; Coutinho, JAP; Wasserscheid, P; Schulz, PS 2019, JOURNAL OF MOLECULAR LIQUIDS, 283, 410-416.
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Odd-Even Effect in the Formation and Extraction Performance of Ionic-Liquid-Based Aqueous Biphasic SystemsBelchior, DCV; Almeida, MR; Sintra, TE; Ventura, SPM; Duarte, IF; Freire, MG 2019, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 58, 19, 8323-8331.
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Synthesis and Characterization of Surface-Active Ionic Liquids Used in the Disruption of Escherichia Coli CellsSintra, TE; Vilas, M; Martins, M; Ventura, SPM; Ferreira, AIMCL; Santos, LMNBF; Goncalves, FJM; Tojo, E; Coutinho, JAP 2019, CHEMPHYSCHEM, 20, 5, 727-735.
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Enhanced dissolution of ibuprofen using ionic liquids as catanionic hydrotropesSintra, TE; Shimizu, K; Ventura, SPM; Shimizu, S; Lopes, JNC; Coutinho, JAP 2018, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 20, 3, 2094-2103.
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Odd-even effect on the formation of aqueous biphasic systems formed by 1-alkyl-3-methylimidazolium chloride ionic liquids and saltsBelchior, DCV; Sintra, TE; Carvalho, PJ; Soromenho, MRC; Esperanca, JMSS; Ventura, SPM; Rogers, RD; Coutinho, JAP; Freire, MG 2018, JOURNAL OF CHEMICAL PHYSICS, 148, 19,
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Understanding the interactions of imidazolium-based ionic liquids with cell membrane modelsMendonca, CMN; Balogh, DT; Barbosa, SC; Sintra, TE; Ventura, SPM; Martins, LFG; Morgado, P; Filipe, EJM; Coutinho, JAP; Oliveira, ON; Barros-Timmons, A 2018, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 20, 47, 29764-29777.
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Aqueous Biphasic Systems Using Chiral Ionic Liquids for the Enantioseparation of Mandelic Acid EnantiomersSilva, FAE; Kholany, M; Sintra, TE; Caban, M; Stepnowski, P; Ventura, SPM; Coutinho, JAP 2018, SOLVENT EXTRACTION AND ION EXCHANGE, 36, 6, 617-631.
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Impact of Surface Active Ionic Liquids on the Cloud Points of Nonionic Surfactants and the Formation of Aqueous Micellar Two-Phase SystemsVicente, FA; Cardoso, IS; Sintra, TE; Lemus, J; Marques, EF; Ventura, SPM; Coutinho, JAP 2017, JOURNAL OF PHYSICAL CHEMISTRY B, 121, 37, 8742-8755.
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Ecotoxicological evaluation of magnetic ionic liquidsSintra, TE; Nasirpour, M; Siopa, F; Rosatella, AA; Goncalves, F; Coutinho, JAP; Afonso, CAM; Ventura, SPM 2017, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 143, 315-321.
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A simple method for preparation of a novel hydrophobic ionic liquid with a per-fluoro-tert-butoxide anionKurnia, KA; Sintra, TE; Danten, Y; Cabaco, MI; Besnard, M; Coutinho, JAP 2017, NEW JOURNAL OF CHEMISTRY, 41, 1, 47-50.
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Evaluating the toxicity of biomass derived platform chemicalsVentura, SPM; de Morais, P; Coelho, JAS; Sintra, T; Coutinho, JAP; Afonso, CAM 2016, GREEN CHEMISTRY, 18, 17, 4733-4742.
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Development of predictive QSAR models for Vibrio fischeri toxicity of ionic liquids and their true external and experimental validation testsDas, RN; Sintra, TE; Coutinho, JAP; Ventura, SPM; Roy, K; Popelier, PLA 2016, TOXICOLOGY RESEARCH, 5, 5, 1388-1399.
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Evaluating Self-buffering Ionic Liquids for Biotechnological ApplicationsLee, SY; Vicente, FA; Silva, FAE; Sintra, TE; Taha, M; Khoiroh, I; Coutinho, JAP; Show, PL; Ventura, SPM 2015, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 3, 12, 3420-3428.
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