João Mano
  Full professor  
  phone: 234370733  
  extension: 33568  
  department: Chemistry  
  office: 29.1.27  
  group: 5 - biomedical and biomimetic materials
  direct url:  
  research group: COMPASS  
Short CV

João F. Mano (CEng, PhD, DSc) is a full professor at the Department of Chemistry of the University of Aveiro (Portugal). During his career he has been teaching courses related to biomaterials science and technology, tissue engineering and physical chemistry of polymers and materials, in both undergraduate and graduate levels. He published three educational-related papers in peer-reviewed international journals and was involved in several training/educational activities.He is the director of both Master and Doctoral Degrees in Biotechnology at the Univ. of Aveiro. 

He belongs to the associate laboratory CICECO – Aveiro Institute of Materials where he is the director of the COMPASS Research Group ( His current research interests include the use of biomaterials and cells towards the development of transdisciplinary concepts especially aimed at being used in regenerative and personalised medicine. In particular, biomimetic and nano/micro-technology approaches have been applied to natural-derived biomaterials and surfaces in order to obtain biomedical devices with improved structural and (multi-)functional properties, or in the engineering of microenvironments to control cell behaviour and organization, to be used in therapies or in drug screening.

João F. Mano is author of 580+ original research or review papers in international journals (19000+ citations, h=69 – Web of Science), about 40 book chapters, and four patents as senior inventor. João F. Mano co-edited 8 special issues in international journals and 3 books. João F. Mano has been invited to review manuscripts from 260+ different international journals and to routinely evaluate projects from numerous private and state funding agencies from 18 different countries. João F. Mano supervised or co-supervised 43 MSc, 20 PhD students, and 30+ post-doctoral fellows. He has been part of a series of scientific societies and editorial boards of international journals, including Tissue Engineering (parts AB and C), Advanced Healthcare Materials, Advanced Engineering Materials, Materials Letters, Polymers, Materials Today Chemistry, and Journal of Bioactive and Compatible Polymers. He has been coordinating or involved in many national and European research projects and participated in the organization of scientific events in the area of polymer/materials science and biomaterials/tissue engineering.

Professor João F. Mano has been member of scientific committees, organizing committees, referee and chairman in different international meetings. He was invited to present 75+ invited/keynote/plenary talks in international conferences including EUROMAT, ESTAC, TERMIS (EU and AP chapters and World conferences), BIOMED, FBPS, NANOMED, COLAOB, ESB, SFB, World Biomaterials Conference, E-MRS, ESAO, EPF or ACS.

João F. Mano has received different honours and awards: (i) fellow of the IUPAC (International Union of Pure and Applied Chemistry) since 2004; (ii) the Stimulus to Excellence Award by the Portuguese Minister for Science and Technology in 2005; (iii) the Materials Science and Technology Prize, attributed by the Federation of European Materials Societies (FEMS) in 2007 (iv) UNESCO Chair on Biomaterials attributed in 2008 from the University of Havana (Cuba); (v) the major BES innovation award in 2010 (at that time, one of the most recognised innovation prize in Portugal); (vi) recipient an Advanced Grant from the European Research Council (ERC-AdG), in 2015; (vii) received the title of Professor@Lorraine from the University of Lorraine, France, in 2018; (viii) recipient a Proof of Concept Grant from the European Research Council (ERC-PoC), in 2018.

Link to the site of the Research Group:

◊ Habilitation in Tissue Engineering, Regenerative Medicine and Stem Cells (Univ. of Minho) - 2012

◊ PhD in Chemistry (Technical University of Lisbon) - 1996

◊ Chemical Engineering degree (I.S.T.) - 1992.

Research Area
Bio-inspired materials: We take nature as a source of endless inspiration for the development of novel classes of polymer-based materials and processes, combining chemistry, materials science, and engineering tools.
Cell and Tissue Engineering: Tissue engineering addresses the scarcity of tissues/organs available for repair and transplantation, by adopting multidisciplinary strategies permitting the ex-vivo creation of implantable hybrid constructs through the integration of biomaterials, therapeutic cells and physicochemical signals.
Nano/micro platforms for biomedicine: Our group focuses on the use of an interplay and cutting-edge nano- and micro-technologies for addressing a multitude of biomedical applications, including those in diagnostics and therapy.
Representative Publications (last 5 years)

J. Borges, J.F. Mano - Molecular interactions driving the layer-by-layer assembly of multilayers. Chemical Reviews, 114, 8883 (2014)

C.A. Custódio, M.T. Cerqueira, A.P. Marques, R.L. Reis, J.F. Mano - Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration. Biomaterials, 43, 23 (2015)

A.M.S. Costa, J.F. Mano - Highly robust hydrogels via a fast, simple and cytocompatible dual crosslinking-based process. Chemical Communications, 51, 15673 (2015)

C.R. Correia, R.P. Pirraco, M.T. Cerqueira, A.P. Marques, R.L. Reis, J.F. Mano - Semipermeable capsules wrapping a multifunctional and self-regulated co-culture microenvironment for osteogenic differentiation. Scientific Reports, 6, 21883 (2016)

M.J. Cardoso, S.G. Caridade, R.R. Costa, J.F. Mano - Enzymatic degradation of polysaccharide-based layer-by-layer structures. Biomacromolecules, 17, 1347 (2016)

A.I. Neto, N.L. Vasconcelos, S.M. Oliveira, D. Ruiz-Molina, J.F. Mano - High-throughput topographic, mechanical, and biological screening of multilayer films containing mussel-inspired biopolymers. Advanced Functional Materials, 26, 2745 (2016)

A.M.S. Costa, J.F. Mano - Solvent-free strategy yields size and shape-uniform capsules. Journal of the American Chemical Society, 139, 1057 (2017)

S. Azevedo, A.M.S. Costa, A. Andersen, I.S. Choi, H. Birkedal, J.F. Mano - Bioinspired ultratough hydrogel with fast recovery, self-healing, injectability and cytocompatibility. Advanced Materials, 29, 1700759 (2017)

J. Borges, M.P. Sousa, G. Cinar, S.G. Caridade, M.O. Guler, J.F. Mano - Nanoengineering hybrid supramolecular multilayered biomaterials using polysaccharides and self-assembling peptide amphiphiles. Advanced Functional Materials, 27, 1605122 (2017)

M.P. Sousa, S.G. Caridade, J.F. Mano - Control of Cell Alignment and Morphology by Redesigning ECM-Mimetic Nanotopography on Multilayer Membranes. Advanced Healthcare Materials, 6, 1601462 (2017)

T.D. Gomes, S.G. Caridade, M.P. Sousa, S. Azevedo, M.Y. Kandur, E.T. Öner, N.M. Alves, J.F. Mano - Adhesive free-standing multilayer films containing sulfated levan for biomedical applications. Acta Biomaterialia, 69, 183 (2018)

B.J. Kim, H. Cho, J.H. Park, J.F. Mano, I.S. Choi - Strategic advances in formation of cell‐in‐shell structures: from syntheses to applications. Advanced Materials, 30, 1706063 (2018)


[see complete list of publications in]

Latest News

ongoing scientific supervisions