Ongoing Supervisions
Ana Catarina Nunes Moreira
PhD Student
Beatriz Amador Lopes Cardoso
PhD Student
Beatriz Duarte Teixeira
PhD Student
Carolina Guerra Neca
PhD Student
Catarina Luís
PhD Student
Cristina Jesus Dias
Junior Researcher
Francisca P. Correia
PhD Student
Gonçalo Miguel Fernandes Simões
PhD Student
Harischandra Potthuri
PhD Student
Inês Aline Pinto Ferreira Alves
PhD Student
Inês Gabado Henriques
Research Fellowship
Inês Margarida Curioso Freitas
PhD Student
João Filipe Lopes da Mota
PhD Student
João Miguel Silvério Feijão
Research Fellowship
Luca Brandolino
Junior Researcher
Margarida F. Domingues
PhD Student
Margarida Henriques Pereira
PhD Student
Maria Vinhas Monteiro
Collaborator
Mariana Tomás de Carvalho
PhD Student
Matilde Rodrigues Lagarto
PhD Student
Patrícia Isabel Silva Rodrigues
PhD Student
Sofia Ribeiro Cotton
Junior ResearcherProjects
Bioengenharia de materiais vivos compostos por células imunes para imunoterapia do cancro do pâncreas (ALIVE)
CoordinatorFundação para a Ciência e a Tecnologia
Bioengenharia de modelos ósseos biomiméticos para o desenvolvimento de terapias anti-tumorais e regenerativas (ÉLPIS)
PartnerOther National
Metastasis Exploration in the Bone Microenvironment - Breast Cancer Edition (METABONE)
PartnerFundação para a Ciência e a Tecnologia
METABONE is a collaborative research project that is all about creating a 3D model in a lab to explore how breast cancer spreads to the bones. To do this, we are using robots to automate tiny tasks and clever liquid capsules that act like mini-labs. The goal is to get an accurate picture of the complex bone environment. This platform is...Supramolecular design of multitactic 3D polymeric biomaterials for spinal cord repair (SUPRANEURO 2)
PartnerFundação para a Ciência e a Tecnologia
Spinal cord injury (SCI) represents one of the leading causes of disability worldwide , being characterized by a permanent loss of motor function and sensory perception owing to the complex pathophysiology and inability of the central nervous system (CNS) to self-regenerate. Currently, the most common therapeutic approaches involve the ...Sustainable 4D hydrogels functionalised with plant-based nanoparticles for bone regeneration in cancer patients (GreenNanoBone)
PartnerEuropean Comission
Biocompatible 4D materials for bone regeneration in MRONJ patients Medication-related osteonecrosis of the jaw (MRONJ) is a rare but severe side effect of bone-targeting agents (BTAs) such as bisphosphonates, prescribed to breast cancer survivors to lower the risk of secondary bone cancer. MRONJ can cause progressive jawbone destruction, leading...Unprecedented photolithographic structuring of novel light-sensitive poly(amino acid) materials- a paradigm shift in delivering biocompatible devices (POLINA)
Local CoordinatorEuropean Comission
Photolitography, which produces geometrical structures through light-induced polymerisation of monomers with high accuracy, precision and spatial resolution, was a key innovation enabler in the drive for high-performance miniature electronics, which had an unprecedented impact on every aspect of our modern life. Geometrically well-defined micros...3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
Maritime Domain Awareness is the combination of activities, events and threats in the maritime environment that could have impact on marine activities and EU territory. During the past decades, advances in Information and Communication Technologies have provided better means to monitor and analyse vessel activity. Today private and public source...Advancing the Regenerative and Translational Potential of Cellular Fibers (CellFi)
PartnerFundação para a Ciência e a Tecnologia
Mesenchymal Stem Cells Scaffold-free Cellular Fibers RegenerationDevelopment of 4D wireless thermometry to target tumor ablation (PTDC/NAN-MAT/3901/2020)
PartnerFundação para a Ciência e a Tecnologia
Thermography Magnetic Nanoparticles Induced Hyperthermia BioprintingDispositivos Supramoleculares Auto-Regulados baseados na Complementaridade dos Pares de Base do ADN: Uma Tecnologia Biomimética e com Reconheciemnto Molecular para Isolar Células Específicas para Aplicações Biomédicas (SUPRASORT)
PartnerFundação para a Ciência e a Tecnologia
Hydralazine: Testing an off-label effect in Castration-Resistant Prostate Cancer (HyTherCaP)
PartnerFundação para a Ciência e a Tecnologia
Prostate cancer (PCa) is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related deaths among men. In Portugal, it is the most incident cancer and the 3rd cause of death (1, 2). Although most of PCa are clinically indolent, a variable proportion of patients develop castration-resistant PCa (CRPC), an aggre...Integrated photonic neuronal probes towards neuromorphic computing (PHEASANT)
PartnerFundação para a Ciência e a Tecnologia
Optical methods have been widely used for stimulation and functional imaging of neural circuits, namely, optogenetics which is a powerful tool for selective excitation or inhibition of specific cell types using light of different wavelengths desirable to stimulate or inhibit a subset of neurons that express the same light-sensitive proteins. The...Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Publications
Temperature-responsive nanomagnetic logic gates for cellular hyperthermia
Silva, RO; Pereira, RA; Silva, FM; Gaspar, VM; Ibarra, A; Millan, A; Sousa, FL; Mano, JF; Silva, NJO
2019, MATERIALS HORIZONS, 6, 3, 524-530.
ISBN:
2051-6355
Stimuli-responsive nanocarriers for delivery of bone therapeutics - Barriers and progresses
Lavrador, P; Gaspar, VM; Mano, JF
2018, JOURNAL OF CONTROLLED RELEASE, 273, 51-67.
Preparation of Well-Dispersed Chitosan/Alginate Hollow Multilayered Microcapsules for Enhanced Cellular Internalization
Ribeiro, C; Borges, J; Costa, AMS; Gaspar, VM; Bermudez, VD; Mano, JF
2018, MOLECULES, 23, 3.
Bioinspired bone therapies using naringin: applications and advances
Lavrador, P; Gaspar, VM; Mano, JF
2018, DRUG DISCOVERY TODAY, 23, 6, 1293-1304.
Bioinstructive Naringin-Loaded Micelles for Guiding Stem Cell Osteodifferentiation
Lavrador, P; Gaspar, VM; Mano, JF
2018, ADVANCED HEALTHCARE MATERIALS, 7, 19.
Bioinstructive microparticles for self-assembly of mesenchymal stem Cell-3D tumor spheroids
Ferreira, LP; Gaspar, VM; Mano, JF
2018, BIOMATERIALS, 185, 155-173.
Design of spherically structured 3D in vitro tumor models -Advances and prospects
Ferreira, LP; Gaspar, VM; Mano, JF
2018, ACTA BIOMATERIALIA, 75, 11-34.
Mesenchymal Stem Cells Relevance in Multicellular Bioengineered 3D In Vitro Tumor Models
Ferreira, LP; Gaspar, VM; Henrique, R; Jeronimo, C; Mano, JF
2017, BIOTECHNOLOGY JOURNAL, 12, 12.
