Maria Margarida Tavares Lopes Almeida
  Emeritus Professor  
  phone: 234 370 354  
  extension: 22 929  
  department: Materials and Ceramic Engineering  
  group: 5 - biomedical and biomimetic materials
  line: 3 - sustainability
  direct url:  
Short CV

Academic degrees:

   - Graduation in Chemical Engineering, IST, Technical University of Lisbon

   - PhD in Materials Science and Engineering, University of Aveiro, Jan 1988


Scientific Interests

-Chemical synthesis of nano and micro-sized calcium phosphate particles for biomedical applications;

- Preparation and characterization of porous scaffolds (polymer/ceramic composites) for biomedical applications;

- Drug releasing systems and composite scaffolds for regenerative medicine and tissue engineering.

Selected Publications

Santos C, Gomes PS, Duarte JA, Franke RP, Almeida MM, Costa MEV, Fernandes MH (2012) “ Relevance of the sterilization-induced effects on the properties of different hydroxyapatite nanoparticles and assessment of the osteoblastic cell response”, J.R.Soc.Interface, Vol 9 / nº 7, 3397-3410

Petrauskaite O, Liesiene J, Santos C, Gomes PS,  Garcia M,  Fernandes MH, Almeida MM, Costa MEV, Juodzbalys G, Daugela P,  Nano-Hydroxyapatite/Cellulose composite scaffold for bone tissue engineering. Journal of Tissue Engineering and Regenerative Medicine, 6, (2012) 34-34.

Computational study of hydroxyapatite properties and surface interactions, A V.Bystrov, E.Costa, C.Santos, M.M.Almeida, A.Kholkin, S.Kopyl, YDekhtyar, A.V.Bystrova, E.V.Paramonova, Proc. of Joint Symposium  ISAF/ECAPD/PFM 2012, pp 1-3

Endres S, Hiebl B, Hagele J, Beltzer C, Fuhrmann R, Jager V, Almeida M, Costa E, Santos C Traupe H, Jung EM, Prantl L, Wilke A, Franke RP (2011)  "Angiogenesis and healing with non-shrinking, fast degradeable PLGA/CaP scaffolds in critical-sized defects in the rabbit femur with or without osteogenically induced mesenchymal stem cells”, Clinical Hemorheology and Microcirculation, 48, 29-40.

C.Santos, M. M Almeida, M.E.V. Costa , “Synthesis and characterization of amino-acid funcionalized hydroxyapatite nanoparticles” Cells and Materials, 2010, 20, 3, 223-223

C.Santos, M.A. Martins, M.M. Almeida and M.E.V. Costa, Influence of the (citric acid/ calcium) ratio on hap particles synthesis, Microscopy and Microanalysis, 15 (2009)85-86

- C.Santos, M.A. Martins, R.-P. Franke, M.M. Almeida, M.E.V. Costa, " Calcium phosphate granules for use as a 5-Fluorouracil delivery system", Ceramics International, 35 (2009) 1587-1594

C.Santos, C.F. Rovath, R.-P. Franke, M.M. Almeida, M.E.V. Costa, " Spray-dried hydroxyapatite-5-Fluorouracil granules as a chemotherapeutic delivery system", Ceramics International, 35(2009)509-513

- T. Scharnweber, J. Fink, R. Fuhrmann, C. Santos, M.M. Almeida, M.E.V. Costa, R.-P. Franke, “Tissue engineering with calcium phosphate composite scaffolds”, Clinical Hemorheology and Microcirculation, 2009, 42, 169

- B. Hiebl, R. Fuhrmann, M.E.V. Costa, M.M. Almeida, R.P. Franke, "In vitro 3D assay to test angiogenic effects of human CD 14+ monocytes seeded on macroporous PLGA/CaP polymers with a CaP nanostructured surface", Clinical Hemorheology and Microcirculation, 40(1) (2008) 37-50

- Tim Scharnweber, Catarina Santos, Ralf-Peter Franke, Maria Margarida Almeida and Maria Elisabete Veira Costa, "Influence of spray-dried hydroxyapatite-5-Fluorouracil granules on cell lines derived from tissues of mesenchymal origin”, Molecules 13, (2008) 2729-2739

- C.Santos, R.-P. Franke, M.M. Almeida and M.E.V. Costa, “Nanoscale Characterization of Hydroxyapatite Particles by Electron Microscopy”, Microscopy and Microanalysis,14(2008)67-70

- M A. Martins, C. Santos, M. M. Almeida, M. E. V. Costa, “Hydroxyapatite micro- and nano-particles: nucleation and growth mechanisms in the presence of citrate species”,Journal of Colloids and Interface Science, (2008), 318, 2, 210-216.

- C.Santos, R.-P. Franke, M.M. Almeida, M.E.V. Costa and M.H. Fernandes “Viability and proliferation of MG-63 osteoblastic cells exposed to hydroxyapatite nanoparticles with different characteristics”, Tissue Engineering Part A, (2008), 14, 5, 810-810.

- R.-P. Franke, M.M. Almeida, M.E.V. Costa, C. Santos, V. Jaeger; A. Wike; R. Fuhrman, “Bridging Critical size defects applying tissue engineering”, Tissue Engineering Part A, (2008),14, 5, 816-816.

R.-P. Franke, C. Santos, T Scharnweber, M. M. Almeida and M. E. V. Costa, “Influence of nanostructured calcium-phosphate particles on rat osteosarcoma cells”, Basic & Clinical Pharmacology & toxicology, (2007), 101, 5, 360-360.