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18 October 2024

Susana Olhero's team registers a patent for magnetic paste for 3D printing

Susana Olhero's team registers a patent for magnetic paste for 3D printing

A team from Universidade de Aveiro (UAveiro), made up of Tânia Carvalho (doctoral student), Susana Olhero (team leader) and researchers Paula Torres and Nilza Ribeiro, has developed a bioceramic magnetic paste for printing components by additive manufacturing, as well as the respective production method, both of which have been granted a national patent. The paste can be used in bone treatments.

These pastes make it possible to develop porous 3D components based on bioceramics (calcium phosphates), which are biocompatible, bioactive and biodegradable, capable of promoting bone regeneration when placed in a bone defect, using a single step in the manufacturing process. The paste contains: calcium, phosphorus and iron, elements that make up natural bone, which helps with bone repair.

In addition to the regenerative function, the magnetic properties of the paste and printed structures allow for the treatment of localized cancer by hyperthermia (they heat up locally, killing cancer cells), without affecting benign cells. It should also be noted that the printed structures obtained with this composite paste do not need to undergo the heat treatment stage (common in ceramics), which allows active agents such as drugs or other biomolecules important for the treatment and/or regeneration of bone tissue to be incorporated into the paste.

We are therefore talking about folders that give rise to 3D structures with multiple functions and a high degree of control over structure and composition. The research team, with members from CICECO- Aveiro Institute of Materials and the Department of Materials and Ceramic Engineering (DEMaC), explains more about the possible applications:

"The present invention consists of bioceramic magnetic pastes, with properties suitable for printing by extrusion additive manufacturing techniques, with the functionalities of promoting the regeneration and reconstruction of bone tissue and cancer treatment by hyperthermia, when an external magnetic field is applied. They can also support active agents in the therapy of localized bone diseases, such as drugs, growth factors and other agents for the treatment of cancers that metastasize to the bone."

With a view to protecting the R&D results developed by UAveiro researchers, this technology has been the subject of a patent application, which was recently granted at national level.

The patented technology was developed within the scope of the project "2BBone- Development of non-sinterizable biomaterials based on calcium phosphates with bi-functionality: regeneration and treatment of bone cancer", led by Susana Olhero (professor at DEMaC) and funded by the Foundation for Science and Technology (FCT), with the support of COMPETE 2020 within the scope of SAICT - Support System for Scientific and Technological Research (PTDC/CTM-CER/29940/2017), a project that ended in 2022.

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