Augusto Pedro

Junior Researcher

Students supervision

2016 | Joana Antunes | MSc in Environmental Biotechnology | University of Aveiro |
“Production and purification of interferon alpha-2b from Escherichia coli
cultures using alternative platforms” | Cosupervisor; Supervisor: Mara Freire

2015 | Rúben Coval | MSc in Biotechnology | University of Beira Interior |
“Lyophilization and a preliminary thermodynamic characterization of
recombinant SCOMT_His6” | Co-supervisor; Supervisor: Luís Passarinha.

2014 | Diana Oliveira | MSc in Biotechnology | University of Beira Interior |
“Stabilization of COMT by experimental design approaches” | Co-supervisor;
Supervisor: Luís Passarinha.

2015 | Maria João Abrantes | BSc in Bioengineering | University of Beira Interior |
“Reconstituição funcional da isoforma membranar da catecol-O-metiltransferase
humana em sistemas não micelares” | Supervisor.

Lecturing

Sep 2012 – Jan 2016 | Practical Courses “Cellular and Molecular Biology” | BSc,
Department of Chemistry, University of Beira Interior.


Sep 2013 – Jan 2016 | Practical Courses “Biotechnology” | MSc, Department of
Chemistry, University of Beira Interior.

Academic Degrees Jury Participation

2017 “Funcionalização de uma matriz cromatográfica superporosa com um líquido
iónico” | João Martins | MSc in Biotechnology | University of Beira Interior | Main
examiner.


2016 “Biosynthesis optimization of STEAP1 protein in Pichia pastoris X33 MUT+” |
Margarida Santos | MSc in Biochemistry | University of Beira Interior | Main
examiner.


2016 "Isolation and purification of STEAP1 protein fragment in Escherichia Coli cells:
a potential target for prostate cancer" | Jorge Fernandes | MSc in Biomedical
Sciences | University of Beira Interior | Main examiner.


2014 "Biosíntese, purificação e biointeracção da proteína humana recombinante
Tau com inibidores da doença de Alzheimer" | Luís Clara | BSc in
Biotechnology | University of Beira Interior | Main examiner.


2014 "Protótipo de uma mitocôndria artificial para aplicação na doença de
Alzheimer" | Joana Coelho | BSc in Bioengineering | University of Beira Interior
| Main examiner.


2014 "Caraterização biofísica e bioquímica da MBCOMT ligada a um inibidor
farmacológico" | Rita Monteiro | BSc in Bioengineering | University of Beira
Interior | Main examiner.

Ongoing Supervisions

Projects

Publications

Advances in Membrane-Bound Catechol-O-Methyltransferase Stability Achieved Using a New Ionic Liquid-Based Storage Formulation

Goncalves, AM; Sousa, A; Pedro, AQ; Romao, MJ; Queiroz, JA; Gallardo, E; Passarinha, LA
2022, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23, 13.

Thermofluor-Based Optimization Strategy for the Stabilization of Recombinant Human Soluble Catechol-O-Methyltransferase

Goncalves, AM; Pedro, AQ; Oliveira, DM; Oliveira, AE; Santos, MFA; Correia, MAS; Queiroz, JA; Gallardo, E; Romao, MJ; Passarinha, LA
2022, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23, 20.

Interferon-Based Biopharmaceuticals: Overview on the Production, Purification, and Formulation

Castro, LS; Lobo, GS; Pereira, P; Freire, MG; Neves, MC; Pedro, AQ
2021, VACCINES, 9, 4.
ISBN: 2076-393X

Efficient Isolation of Bacterial RNAs Using Silica-Based Materials Modified with Ionic Liquids

Pereira, P; Pedro, AQ; Neves, MC; Martins, JC; Rodrigues, I; Freire, MG; Sousa, F
2021, LIFE-BASEL, 11, 10.
ISBN: 2075-1729

Impact of glycerol feeding profiles on STEAP1 biosynthesis by Komagataella pastoris using a methanol-inducible promoter

Duarte, DR; Barroca-Ferreira, J; Goncalves, AM; Santos, FM; Rocha, SM; Pedro, AQ; Maia, CJ; Passarinha, LA
2021, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 105, 11, 4635-4648.
ISBN: 1432-0614

Enhanced performance of polymer-polymer aqueous two-phase systems using ionic liquids as adjuvants towards the purification of recombinant proteins

Castro, LS; Pereira, P; Passarinha, LA; Freire, MG; Pedro, AQ
2020, SEPARATION AND PURIFICATION TECHNOLOGY, 248.
ISBN: 1873-3794

Brain-Targeted Delivery of Pre-miR-29b Using Lactoferrin-Stearic Acid-Modified-Chitosan/Polyethyleneimine Polyplexes

Pereira, P; Barreira, M; Cruz, C; Tomas, J; Luis, A; Pedro, AQ; Queiroz, JA; Sousa, F
2020, PHARMACEUTICALS, 13, 10.
ISBN: 1424-8247

Integrated Extraction-Preservation Strategies for RNA Using Biobased Ionic Liquids

Quental, MV; Pedro, AQ; Pereira, P; Sharma, M; Queiroz, JA; Coutinho, JAP; Sousa, F; Freire, MG
2019, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 7, 10, 9439-9448.

Smoothing membrane protein structure determination by initial upstream stage improvements

Pedro, AQ; Queiroz, JA; Passarinha, LA
2019, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 103, 14, 5483-5500.
ISBN: 1432-0614

Effect of Chromatographic Conditions on Supercoiled Plasmid DNA Stability and Bioactivity

Azevedo, GM; Valente, JFA; Sousa, A; Pedro, AQ; Pereira, P; Sousa, E; Queiroz, JA
2019, APPLIED SCIENCES-BASEL, 9, 23.
ISBN: 2076-3417

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