3D bioprinting construct for the diminishing of bone tumor and progression of bone tissue regeneration: Diagnosis of phenotyping in the cellular model and screening as a therapeutic platform

Descrição

Bone tissue engineering offers a promising solution for restoring damaged bone tissue. However, current methods face limitations in creating disease models for identifying target genes in tumour recurrence, which hinders the development of preclinical strategies. In this context, the EU-funded TissueEng project aims to use 3D bioprinting to develop a biosensor-impregnated 3D construct for screening bone tumour behaviours and bone defect recovery. The goal is to create a multifunctional 3D bioprinting hydrogel that mimics disease models and identifies targets for osteosarcoma treatment. The project will take a multidisciplinary approach. The findings are expected to impact public healthcare sustainability, benefiting patients across all socio-economic levels.

Coordenador

João Mano

Coordenação

Universidade de Aveiro (UA)

Participantes

UNIVERSITY OF MICHIGAN THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Financiadores

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