abstract
Bioactive glasses (BGs) are known for their selective ability to (i) form a mechanically strong interfacial bond with hard (bone) or soft tissues (gingivae or cartilages) (i.e., silica-, silica-phosphate-, phosphate-, boratephosphate-, or silica-phosphate-borate-based BGs); or (ii) serve as reservoirs for fast-release of therapeutic (osteogenic, angiogenic, anticarcinogenic, or antimicrobial) ions (i.e., phosphate-based BGs and mesoporous BGs). The strength of the bone bond yielded by the osteoproductive-capable BGs is generally equivalent to, or higher than the bone strength. The resorbability of phosphate-based BG is dependent on the content of network formers and cross-linkers. All BGs elicit excellent biochemical compatibility. However, their fracture toughness is typically less than and the elastic modulus is greater than those of bone, indicating that most BGs have suboptimal biomechanical compatibility when used in load-bearing applications. One promising approach to overcome this problem is the development of BGs in coating form, applied to the surface of load-bearing endosseous implants. This work critically assesses BG thin-layers fabricated by the radio-frequency magnetron sputtering method, an industry-ready large-scale physical vapour deposition technology. It is demonstrated that, despite the relative lack of attention paid to this technology, it enables the development of unique BG coatings with efficacious therapeutic capabilities. Here, we present an overview of the most relevant developments achieved thus far, along with the remarkable advantages, drawbacks to overcome, and future perspectives with the intention of highlighting the vast possibilities of this specific field of research.
keywords
PULSED-LASER DEPOSITION; PHOSPHATE-BASED GLASSES; MECHANICAL-PROPERTIES; CERAMIC COATINGS; BIOGLASS FILMS; STRUCTURAL-CHARACTERIZATION; ELECTROPHORETIC DEPOSITION; SURFACE CHARACTERISTICS; THERMAL-EXPANSION; STAINLESS-STEEL
subject category
Chemistry; Materials Science; Physics
authors
Stan, GE; Montazerian, M; Shearer, A; Stuart, BW; Baino, F; Mauro, JC; Ferreira, JMF
our authors
José Maria da Fonte Ferreira
Retired Professoracknowledgements
The POLONEZ BIS 1 "BAGBONE", Project no. 536651 supported by the Polish National Science Centre is acknowledged by JMFF. GES thanks to the Core Program of the National Institute of Materials Physics within the National Research Development and Innovation Plan 2022-2027, carried out with the support of the Romanian Ministry of Research, Innovation and Digitalization under the project PC1-PN23080101.