abstract
Solid-state nuclear magnetic resonance (solid-state NMR) is an essential tool for probing local structure and dynamics in complex materials, yet its uptake in the broader chemistry community has remained limited by technical and operational barriers. The PANACEA project established a pan-European infrastructure to transform solid-state NMR into a community-ready analytical technique by combining state-of-the-art instrumentation, coordinated user access, and targeted technological innovation. Over three years, PANACEA enabled over 90 user projects across chemistry and materials science, while driving advances in DNP methods, probe design, ultra-fast MAS, and interoperable software platforms such as EasyNMR and CHEMeDATA. This article presents the main outcomes of the initiative, illustrating how infrastructure-driven research and guided access can broaden the impact of solid-state NMR and integrate it into mainstream chemical workflows.
authors
Raphaële Coulon, David Gajan, Wassilios Papawassiliou, Andrew J. Pell, Judith Schlagnitweit, Franck Fayon, Pierre Florian, Dominique Massiot, Armin Afrough, Dennis W. Juhl, Thomas Vosegaard, Linda Cerofolini, Moreno Lelli, Massimo Lucci, Claudio Luchinat, Ruud L.E.G. Aspers, Jennifer S. Gómez, Arno P.M. Kentgens, Sander F.H. Lambregts, Y.T. Angel Wong, Luís Mafra, Ildefonso Marin-Montesinos, João Rocha, Mariana Sardo, Ulrika Brath, Göran Karlsson, Arthur C. Pinon, Staffan Schantz, Mária Šoltésová, Stephanie Bachmann, Steven P. Brown, Dinu Iuga, W. Trent Franks, Anjali Menakath, Lucio Frydman, Frederic Mentink-Vigier, Robert W. Schurko, Kristof Grohe, Frank Engelke, James Kempf, Armin Purea, Christian Reiter, Sebastian Wegner, Vanessa Castro, Carlos Cobas, Damien Jeannerat, Felipe Seoane, Esther Vaz, Daniel Jardon Alvarez, Michal Leskes, Federico De Biasi, Guido Pintacuda, Anne Lesage
our authors
Ildefonso Marin Montesinos
Assistant Researcher
João Rocha
Full Professor
Luís Mafra
Principal Researcher
Mariana Coutinho Sardo
Assistant ResearcherProjects
A Pan-European Solid-State NMR Infrastructure for Chemistry-Enabling Access (PANACEA)
Associated Laboratory CICECO-Aveiro Institute of Materials (LA/P/0006/2020)
Collaboratory for Emerging Technologies, CoLab (EMERGING TECHNOLOGIES)
acknowledgements
This work was conducted within the European PANACEA network, which brings together major research infrastructures to advance the use of solid-state NMR in chemistry across Europe. PANACEA has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No. 101008500 (2021-2026). The Lyon and Orléans laboratories also received support from Infranalytics (FR2054). The UK High-Field Solid-State NMR National Research Facility is funded by the Engineering and Physical Sciences Research Council with a contribution from the Biotechnology and Biological Sciences Research Council) via grants EP/F017901/1, EP/R029946/1, and EP/T015063/1. The National High Magnetic Field Laboratory (NHMFL) is funded by the National Science Foundation Division of Materials Research (DMR-2128556) and the State of Florida. This work was developed within the scope of the project CICECO – Aveiro Institute of Materials, UID/50011/2025 & LA/P/0006/2020 (DOI 10.54499/LA/P/0006/2020), financed by national funds through the FCT/MCTES (PIDDAC). The CERM/CIRMMP Laboratory (Univ. of Florence) gratefully acknowledges the Italian Ministero dell’Istruzione, dell’Università e della Ricerca through PRIN 2017A2KEPL, PRIN 2022 PNRR - P2022N2XWH the support and the use of resources of Instruct-ERIC, a landmark ESFRI project, and specifically the CERM/CIRMMP Italy center; EOSC-Life“Providing an open collaborative space for digital biology in Europe” (H2020, contract no. 824087),“Glytunes” Marie Sklodowska-Curie Action (MSCA) Innovative Training Networks (ITN) H2020- MSCA-ITN-2020 (contract no. 956758) and Progetto Dipartimenti di Eccellenza 2023-2027 to the Department of Chemistry “Ugo Schiff” of the University of Florence and the project “Potentiating the Italian Capacity for Structural Biology Services in Instruct Eric (ITACA.SB)” (Project n◦ IR0000009) within the call MUR 3264/2021 PNRR M4/C2/L3.1.1, funded by the European Union NextGenerationEU, for funding support.