resumo
Bacterial cellulose (BC) is a nanocellulose form produced by some nonpathogenic bacteria. BC presents unique physical, chemical, and biological properties that make it a very versatile material and has found application in several fields, namely in food industry, cosmetics, and biomedicine. This review overviews the latest state-of-the-art usage of BC on three important areas of the biomedical field, namely delivery systems, wound dressing and healing materials, and tissue engineering for regenerative medicine. BC will be reviewed as a promising biopolymer for the design and development of innovative materials for the mentioned applications. Overall, BC is shown to be an effective and versatile carrier for delivery systems, a safe and multicustomizable patch or graft for wound dressing and healing applications, and a material that can be further tuned to better adjust for each tissue engineering application, by using different methods.
palavras-chave
MESENCHYMAL STEM-CELLS; IN-VITRO; MECHANICAL-PROPERTIES; COMPOSITE SCAFFOLDS; NANOFIBROUS SCAFFOLD; CONTROLLED-RELEASE; BIOGLASS SCAFFOLD; DRUG-RELEASE; MUSCLE-CELLS; NANOCELLULOSE
categoria
Biochemistry & Molecular Biology; Biotechnology & Applied Microbiology
autores
Carvalho, T; Guedes, G; Sousa, FL; Freire, CSR; Santos, HA
nossos autores
Carmen Sofia da Rocha Freire Barros
Investigador Coordenador
Filipa Lourosa Sousa
Investigador Júnior
Gabriela Guedes
Bolseiro de investigação
Tiago Carvalho
Estudante de doutoramentoGrupos
G2 - Materiais Fotónicos, Eletrónicos e Magnéticos
G4 - Materiais Renováveis e Economia Circular
agradecimentos
T.C. and G.G. contributed equally to this work. T.C. acknowledges Fundacao para a Ciencia e a Tecnologia (FCT), for the Ph.D. grant SFRH/BD/130458/2017. F.L.S. acknowledges FCT for the researcher contract IF/00222/2015. H.A.S. acknowledges financial support from the HiLIFE Research Funds and the Sigrid Juselius Foundation.