Recent Developments in Chitosan-Based Micro/Nanofibers for Sustainable Food Packaging, Smart Textiles, Cosmeceuticals, and Biomedical Applications
authors Tien, ND; Lyngstadaas, SP; Mano, JF; Blaker, JJ; Haugen, HJ
nationality International
journal MOLECULES
author keywords chitosan nanofibers; sustainable food packaging; advanced textiles; biofunctionalized materials; wound care; skin graft substitute; dermal regeneration
keywords SHELL STRUCTURE NANOFIBERS; IN-VITRO; ELECTROSPUN NANOFIBERS; ANTIBACTERIAL ACTIVITY; GRAFTED CHITOSAN; FABRICATION; SCAFFOLDS; MEMBRANES; FIBERS; DERIVATIVES
abstract Chitosan has many useful intrinsic properties (e.g., non-toxicity, antibacterial properties, and biodegradability) and can be processed into high-surface-area nanofiber constructs for a broad range of sustainable research and commercial applications. These nanofibers can be further functionalized with bioactive agents. In the food industry, for example, edible films can be formed from chitosan-based composite fibers filled with nanoparticles, exhibiting excellent antioxidant and antimicrobial properties for a variety of products. Processing 'pure' chitosan into nanofibers can be challenging due to its cationic nature and high crystallinity; therefore, chitosan is often modified or blended with other materials to improve its processability and tailor its performance to specific needs. Chitosan can be blended with a variety of natural and synthetic polymers and processed into fibers while maintaining many of its intrinsic properties that are important for textile, cosmeceutical, and biomedical applications. The abundance of amine groups in the chemical structure of chitosan allows for facile modification (e.g., into soluble derivatives) and the binding of negatively charged domains. In particular, high-surface-area chitosan nanofibers are effective in binding negatively charged biomolecules. Recent developments of chitosan-based nanofibers with biological activities for various applications in biomedical, food packaging, and textiles are discussed herein.
publisher MDPI
isbn 1420-3049
year published 2021
volume 26
issue 9
digital object identifier (doi) 10.3390/molecules26092683
web of science category 23
subject category Biochemistry & Molecular Biology; Chemistry, Multidisciplinary
unique article identifier WOS:000650664400001
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journal analysis (jcr 2019):
journal impact factor 3.267
5 year journal impact factor 3.589
category normalized journal impact factor percentile 56.714
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