Zirconia-doped nanoparticles: organic coating, polymeric entrapment and application as dual-imaging agents

resumo

Zirconia nanoparticles doped with Eu3+, Tb3+ and Gd3+ ions have been synthesized following the benzyl alcohol route. The nanoparticles were coated with N-hydroxydodecanamide and encapsulated in PLGA-b-PEG-COOH nanomicelles. The magnetic and fluorescent properties of these hybrid nanocarriers were investigated, proving them to be potential dual-imaging contrast agents.

palavras-chave

ONE-STEP SYNTHESIS; OPTICAL SPECTROSCOPY; ZRO2 NANOCRYSTALS; CONTRAST AGENTS; SCALE SYNTHESIS; DRUG-DELIVERY; OXIDE; PHOTOLUMINESCENCE; NANOCOMPOSITES; TOXICITY

categoria

Materials Science

autores

Rebuttini, V; Pucci, A; Arosio, P; Bai, X; Locatelli, E; Pinna, N; Lascialfari, A; Franchini, MC

nossos autores

Grupos

agradecimentos

The work was partly supported with the funds of the Nanother EU-FP7 project CP-IP (no. 213631-2). This work was partially supported by FCT grants SFRH/BPD/71671/2010, SFRH/BD/68810/2010, and SFRH/BD/45177/2008.

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