Preparation of porous hydroxyapatite particles to be used as drug delivery systems
authors Martins, MA; Santos, C; Costa, MEV; Almeida, MM
editors Martins, R; Fortunato, E; Ferreira, I; Dias, C
nationality International
journal ADVANCED MATERIALS FORUM II
author keywords hydroxyapatite; nanoparticles; porous particles; drug delivery; bioceramics
keywords RELEASE
abstract Porous apatite particles with an average diameter of 3-4 mum were produced by spray drying a suspension of apatite nanoparticles, which were previously obtained by precipitation in a calcium/citrate/phosphate solution. The high surface area of the porous particles indicates a highly porous structure. The so produced spray dried apatite particles have the capability to adsorb and release a model drug compound (salicylic acid) in solutions at physiological pH.
publisher TRANS TECH PUBLICATIONS LTD
issn 0255-5476
isbn 0-87849-941-5
year published 2004
volume 455-456
beginning page 353
ending page 357
web of science category Materials Science, Multidisciplinary
subject category Materials Science
unique article identifier WOS:000222018500076

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