Preparation of porous hydroxyapatite particles to be used as drug delivery systems
| authors | Martins, MA; Santos, C; Costa, MEV; Almeida, MM |
| editors | Martins, R; Fortunato, E; Ferreira, I; Dias, C |
| nationality | International |
| journal | ADVANCED MATERIALS FORUM II |
| author keywords | hydroxyapatite; nanoparticles; porous particles; drug delivery; bioceramics |
| keywords | RELEASE |
| abstract | Porous apatite particles with an average diameter of 3-4 mum were produced by spray drying a suspension of apatite nanoparticles, which were previously obtained by precipitation in a calcium/citrate/phosphate solution. The high surface area of the porous particles indicates a highly porous structure. The so produced spray dried apatite particles have the capability to adsorb and release a model drug compound (salicylic acid) in solutions at physiological pH. |
| publisher | TRANS TECH PUBLICATIONS LTD |
| issn | 0255-5476 |
| isbn | 0-87849-941-5 |
| year published | 2004 |
| volume | 455-456 |
| beginning page | 353 |
| ending page | 357 |
| web of science category | Materials Science, Multidisciplinary |
| subject category | Materials Science |
| unique article identifier | WOS:000222018500076 |
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