Ana Luísa Daniel-da-Silva graduated in Chemical Engineering (2000) by Instituto Superior Técnico (Lisbon, Portugal) in 2000 and got her PhD degree in Materials Science, cum laude, from University of Alicante (Spain) in 2005. Since June 2009 she is Researcher at CICECO-Aveiro Institute of Materials and Chemistry Department of the University of Aveiro (UA). Her main scientific interests concern the development of nanostructured materials including functional nanoparticles and nanocomposites for applications in nanomedicine, bionanotechnology and water remediation. In particular, she is interested in novel strategies for surface modification with biopolymers and synthetic routes for preparing nanomaterials with innovative and enhanced properties, aiming the development of green nanosorbents and biocompatible nanomaterials. She has authored or co-authored 3 patent applications, 7 book chapters and more than 60 papers in international peer reviewed journals. In addition she has co-edited the book ‘Nanocomposite Particles for Bio-applicationsMaterials and Bio-interfaces’ (Pan Stanford, 2011). She has completed the supervision of 17 MSc theses and 17 graduation projects. At the present she (co-)supervises the scientific work of 3 Post-Doc fellows, 3 PhD students, 1 MSc student and 3 MSc researchers hired in the scope of the projects that are in progress. She has been strongly involved to several teaching activities namely by lecturing topics for post-graduation students within the subjects Nanochemistry and Frontiers of Inorganic Chemistry. As part of her academic activities she has been involved in communicating chemistry for non-specialized audiences, in particular issues related to Nanotechnology and Nanomaterials.
Academic Qualifications
- PhD degree in Materials Science, University of Alicante (Spain), June 2005
Thesis title: “Synthesis, characterization and adhesive properties of isocyanate ended quasi-prepolymers based adhesives”
- BSc degree in Chemical Engineering (5 year program), IST, Lisbon (Portugal), April 2000
Final Project title: “Production of Lignosulphonates using the residual liquor obtained in the wood pulp production (sulphite process)”
Scientific and professional activities
-Present time: Assistant Researcher, Chemistry Department and CICECO, University of Aveiro
-2005-2009: Postdoctoral fellow at CICECO, University of Aveiro
-February-July 2000: Analyst at the company F. LIMA SA (Lisbon)
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KEYWORDS: Functional nanomaterials; Nanocomposites; Colloidal Nanoparticles; Surface Modification; Environmental Nanotechnology; Biomaterials
1. ENGINEERED SURFACE FUNCTIONALIZATION OF NANOPARTICLES FOR BIOAPPLICATIONS AND WATER TREATMENT
FOR WATER TREATMENT - Novel strategies for rational surface modification of magnetic nanoparticles with polymers extracted from renewable sources. The final aim is the development of low-cost high performance green nanosorbents for the uptake of emerging organic pollutants from water. Study of interface phenomena. Understanding sorption mechanisms.
Key Contributions:
S. F. Soares, T. Fernandes, M. Sacramento, T. Trindade, A. L. Daniel-da-Silva, Magnetic quaternary chitosan hybrid nanoparticles for the efficient uptake of diclofenac from water, Carbohydrate Polymers 2019, 203, 35-44
T. Fernandes, S. F. Soares, T. Trindade, A. L. Daniel-da-Silva, Magnetic Hybrid Nanosorbents for the Uptake of Paraquat from Water, Nanomaterials 2017, 7, 68
S. F. Soares, T. R. Simões, M. António, T. Trindade, A. L. Daniel-da-Silva, Hybrid Nanoadsorbents for the magnetically assisted removal of metoprolol from water, Chemical Engineering Journal 2016, 302, 560-569
S. F. Soares; T. Fernandes; T. Trindade; A. L. Daniel-da-Silva, Surface engineered magnetic biosorbents for water treatment, In. Green Adsorbents for Pollutant Removal. Environmental Chemistry for a Sustainable World, vol 18, 301-342, Springer 2018
FOR BIOAPPLICATIONS - Novel chemical strategies for the surface functionalization of inorganic nanocrystals (magnetic, plasmonic) for targeting/detecting biomolecules (e.g. proteins, biomarkers) that are in trace amounts in biofluids.
Key Contributions:
M. António, J. Nogueira, R. Vitorino, A. L. Daniel-da-Silva, Functionalized Gold Nanoparticles for the Detection of C-Reactive Protein, Nanomaterials 2018, 8, 200
C. Couto, R. Vitorino, A. L. Daniel-da-Silva, Gold nanoparticles and bioconjugation: a pathway for proteomic applications, Critical Reviews in Biotechnology 2017, 37, 238-250
R. Oliveira-Silva, J. P. Costa, R. Vitorino, A. L. Daniel-da-Silva, Magnetic chelating nanoprobes for enrichment and selective recovery of metalloproteases from human saliva, Journal Materials Chemistry B 2015, 3, 238-249
J. P. Costa, R. Oliveira-Silva, A. L. Daniel-da-Silva, R. Vitorino, Bionanoconjugation for proteomics applications – an overview, Biotechnology Advances 2014, 32(5), 952-970

2. POLYMER-BASED FUNCTIONAL NANOCOMPOSITES
Functional bionanocomposites merge the intrinsic functionalities of inorganic nanofillers and the biointerfaces of biopolymers. These are materials with unique responsive features of interest for biomedical, food and environmental applications. The properties of the bionanocomposites depend on the chemical nature of the organic and inorganic components but also depend on the interaction and synergy of these components, which are keys aspects investigated in this research line.
Key Contributions:
- S. Fateixa, R. S. Carvalho, A. L. Daniel-da-Silva, H. I. S. Nogueira, T. Trindade, Luminescent Carrageenan Hydrogels Containing Lanthanopolyoxometalates, European Journal of Inorganic Chemistry 2017, 43, 4976-4981.
- S. F. Soares, T. Trindade, A. L. Daniel-da-Silva, Carrageenan-Silica Hybrid Nanoparticles Prepared by a Non-Emulsion Method, European Journal of Inorganic Chemistry 2015, 27, 4588-4594.
- A. C. Estrada, A. L. Daniel-da-Silva, T. Trindade, Photothermally enhanced drug release by k-carrageenan hydrogels reinforced with multiwalled carbon nanotubes, RSC Advances 2013, 3, 10828-10836.
- A .M. Salgueiro, A. L. Daniel-da-Silva, S. Fateixa,T. Trindade, k-carrageenan hydrogel nanocomposites with release behavior mediated by morphological distinct Au nanofiller, Carbohydrate Polymers 2013, 91, 100-109.
- A. L. Daniel-da-Silva, J. Moreira, R. Neto, A. C. Estrada, A. M. Gil, T. Trindade, Impact of magnetic nanofillers in the swelling and release properties of k-carrageenan hydrogel nanocomposites, Carbohydrate Polymers 2012, 87, 328-335.
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Ongoing projects
HOTSPOT- Novel upconversion nanoparticles for multimodal therapy of melanoma: pHOtothermal Therapy, PhOtodynamic therapy and chemotherapy. 2018-2021. (Team membre)
IF/00405/2014/CP1222/ CT0007- Stimuli-responsive bionanocomposites: towards remotely controlled nanomaterials. 2015-2020. Coordinator
SGH-Smart Green Homes; 2016-2019 (Team member)
PROTEUS - Produtos e Tecnologias para o sector do Eucalyptus Globulus; 2016-2019 (Team member)
Past projects
PTDC/MAR-BIO/3533/2012 - Remediação de águas salinas sob a influência de multicontaminantes (poluentes inorgânicos e emergentes), através da aplicação de nanopartículas magnéticas e resíduos biológicos: avaliação do risco ecológico e humano. 2013-2015; (Team member) EXPL/BBB-BEP/0317/2012 - Desenvolvimento de uma plataforma em nanoescala para o enriquecimento de proteases. 2013-2014; (Team member) CERN/FP/123585/2011 - Perturbed Angular Correlations and Electron Channeling Experiments at ISOLDE - applied materials research with nuclear techniques, training and development. 2012 – 2014;(Team member) PTDC/CTM-NAN/120668/2010 - Nanomaterials for the uptake of pollutant metal ions: efficiency. selectivity and recyclability. 2012-2015; (Team member) PTDC/SAU-TOX/120953/2010 - Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials. 2012 -2014; (Team member)
CERN/FP/116320/2010 - Perturbed Angular Correlations and Electron Channeling Experiments at ISOLDE-applied materials research with nuclear techniques, training and development; 2011 – 2012; (Team member) ERA-Eula/0003/2009 - Magnetotransduction: development of magnetic nanoparticle-viral vector complexes for therapeutic gene delivery in the senile brain. 2010 – 2012;(Team member) CERN/FP/109357/2009 - Research on Magnetic and Multiferroic Materials using Radioactive Isotopes at ISOLDE-CERN. 2010 – 2011; (Team member) NANO/NMed-SD/0140/200 - Integrated Lab On Chip Platforms for Medical Diagnostics. 2009 – 2011; (Team member) PTDC/QUI/67712/2006 - Nanochemistry of magnetic/luminescent composites for in vitro medical diagnosis applications. 2008 – 2010; (Team member) PTDC/SAU-BEB/66896/2006 - Implantable scaffolds for local osteo-sarcoma chemotherapy. 2007 – 2010;(Team member)
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PhD Theses
-Maria de Almeida Vasconcelos António; SFRH/BD/136881/2018; Supervisor: AL Daniel-da-Silva; Co-supervisor: Rui Vitorino (ibimed). (2018-ongoing)
-João Tiago Moniz Fernandes; SFRH/BD/130934/2017; Supervisor: Tito Trindade; Co-supervisor: AL Daniel-da-Silva. (2017-ongoing)
-Sofia Farias Soares; SFRH/BD/121366/2016; Supervisor: AL Daniel-da-Silva; Co-supervisor: Tito Trindade. (2017-ongoing)
MSc Theses
18. Diogo Lopes, Multifunctional photocatalysts composites based on titania, Supervisors: Andrei Kavaleuski and A.L. Daniel-da-Silva (ongoing).
17. Adriana Bernardes, Liquid-phase exfoliation of highly oriented pyrolytic graphite and its oxidation by air-ozone atomization, Supervisors: Bruno Neves (Graphenest) and A.L. Daniel-da-Silva (2018).
16. Cátia Leal, Removal of AOX from paper pulp effluents using photocatalysis, Supervisors: A.L. Daniel-da-Silva and Paula Pinto (RAIZ) (2018).
15. Maria António, Detection of C-reactive protein in biological samples using functionalized gold nanoparticles, Supervisors: A.L. Daniel-da-Silva and Rui Vitorino (2017).
14. Joana Maia, Nanostructured additives for concrete, Supervisors: Frederico Maia and Cláudia Rocha (Smallmatek) and A.L. Daniel-da-Silva (2017).
13. Tiago Polónio, Treatment of the effluents of Kraft pulp industry using photocatalytic oxidation, Supervisors: António Mendes de Sousa (RAIZ) and A.L. Daniel-da-Silva (2016).
12. Tânia Silva, Study of alternative resins in decorative paints, Supervisors: Vasco Lopes (CIN) and A.L. Daniel-da-Silva (2015).
11. Ana Raquel Fernandes, Laccase immobilization onto magnetic nanoparticles: study and applications, Supervisors: A. Xavier and A.L. Daniel-da-Silva (2015).
10. Tânia Simões, Magnetic removal of pollutants from water using green nanocomposites, Supervisors: A.L. Daniel-da-Silva and T. Trindade (2015).
9. Marta Julia Busse, Bionanocomposites of Fe3O4/SiO2 and alginate for the magnetic removal of Cr(III) species in water, Supervisors: T. Trindade and A.L. Daniel-da-Silva (2014).
8. Catarina Rebelo, Gold nanocomposites for controlled drug release, Supervisor: A.L. Daniel-da-Silva (2014).
7. Bianca Creaney, Nano-adsorventes para remoção magnética de corantes orgânicos de águas, Supervisors: A.L. Daniel-da-Silva (2013).
6. Maria Graça Oliveira, Hidrogéis nanocompósitos de ouro para aplicações em libertação controlada de fármacos, Supervisors: A.L. Daniel-da-Silva (2012).
5. Luís Melo, Libertação de prata ionica em nanocompositos, Supervisors: Tito Trindade and A.L. Daniel-da-Silva (2012).
4. Rui Pedro Silva, Funcionalização de nanopartículas magnéticas para o desenvolvimento de um sistema de caraterização de proteases, Supervisors: Rui Vitorino and A.L. Daniel-da-Silva (2012).
3. Ana Margarida Salgueiro, Hidrogeis termosensiveis compósitos contendo nanobastonetes de ouro, Supervisors: A. L. Daniel-da-Silva and Tito Trindade (2011).
2. Cristina Schitco, Thermo conductivity and electrical properties of PVDF/Cu nanocomposites, Supervisors: Paula Vilarinho and A.L. Daniel-da-Silva (2011).
1. Joana da Silva Moreira, Estudo de síntese e cinética de libertação em bionanocompósitos, Supervisors: Tito Trindade and A.L. Daniel-da-Silva (2010).
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Books 
T. Trindade; A. L. Daniel-da-Silva (Eds), Nanocomposite particles for bio-applications – materials and biointerfaces, Pan Stanford Publishing, 2011, ISBN: 978-981-4267-78-6
Book Chapters
7. S. F. Soares; T. Fernandes; T. Trindade; A. L. Daniel-da-Silva, Surface engineered magnetic biosorbents for water treatment, In. Green Adsorbents for Pollutant Removal. Environmental Chemistry for a Sustainable World, vol 18, 301-342, Edited by Grégorio Crini and Eric Lichftouse, Published by Springer Nature, Cham, 2018. ISBN: 978-3-319-92110-5; DOI:10.1007/978-3-319-92111-2_9
6. P. L. Lopes, N. B. Barroca, A. L. Daniel-da-Silva, B. J. Leite Ferreira, Application of chitosan based materials for drug delivery, In. Frontiers in Biomaterials - Chitosan Based Materials and its Applications Volume 3, Chapter 8, 181-248, Edited by Guilherme Luiz Dotto, Sergio Paulo Campana-Filho and Luiz Antonio de Almeida Pinto, Published by Bentham Science Publishers Ltd, 2017, ISBN 978-1-68108-486-2, eISBN 978-1-68108-485-5
5. F. L. Sousa, A. L. Daniel-da-Silva, N. J. O. Silva, T. Trindade, Bionanocomposites for the magnetic removal of water pollutants, In. Eco-friendly Polymer Nanocomposites: Chemistry and Applications, Chapt 9, Springer, 2015, Edited by Vijay Kumar Thakur, ISBN: 978-81-322-2473-0
4. M. Cova, R. Oliveira-Silva, J. A. Ferreira, R. Ferreira, F. Amado, A. L. Daniel-da-Silva, R. Vitorino, Glycoprotein Enrichment Method Using a Selective Magnetic Nano-Probe Platform (MNP) Functionalized With Lectins, In. Clinical Proteomics-Methods and Protocols, Series “Methods in Molecular Biology”, vol.1243, Chapter 5, 83-100. Edited by Antonia Vlahou and Manousos Makridakis. Published by Humana Press, New York 2015. ISBN 978-1-4939-1871-3; DOI 10.1007/978-1-4939-1872-0_5
3. A. L. Daniel-da-Silva, T. Trindade, Biofunctional composites of polysaccharides containing inorganic nanoparticles, In. Nanocomposites, Intech – Open Access Publisher, 2011. ISBN: 978-953-308-55-0
2. A. S. Pereira, A. L. Daniel-da-Silva, T. Trindade, From nanoparticles to nanocomposites: an Overview In. Nanocomposite particles for bio-applications– materials and biointerfaces, Chapt. 1. Pan Stanford Publishing, 2011. ISBN: 978-981-4267-78-6
1. A. L. Daniel-da-Silva, N. J. O. Silva, T. Trindade, A. M. Gil, Biocomposites containing magnetic nanoparticles, In. Nanocomposite particles for bio-applications– materials and biointerfaces, Chapt. 8, Pan Stanford Publishing, 2011, ISBN: 978-981-4267-78-6
Patents
2. Patente de Invenção Nacional nº 108283, 13-03-2015 (Portuguese Patent) Ana Luísa Daniel da Silva; Tito Trindade; Sofia F. Soares Partículas híbridas de biopolimero-silica e método para a sua produção (Biopolymer-silica hybrid particles and Method for their production)
1. Patente de Invenção Nacional nº 104136, 22-01-2010 (Portuguese Patent) Mª Helena Fernandes, Paula Mª Vilarinho, Ana Luísa Silva, Natália Barroca Método de preparação de suportes porosos compósitos de base polimérica para aplicação em engenharia de tecidos
SCI Papers
67. S. F. Soares, T. Fernandes; M. Sacramento, T. Trindade, A. L. Daniel-da-Silva Magnetic quaternary chitosan hybrid nanoparticles for the efficient uptake of diclofenac from water Carbohydrate Polymers 2019, 203, 35-44 DOI: 10.1016/j.carbpol.2018.09.030
66. J. Nogueira, M. António, S. M. Mikhalev , S. Fateixa, T. Trindade, A. L. Daniel-da-Silva Porous Carrageenan-Derived Carbons for Efficient Ciprofloxacin Removal from Water Nanomaterials 2018, 8, 1004 DOI:10.3390/nano8121004
65. S. R. D. Gamelas, A. T. P. C. Gomes, N. M. M. Moura, M. A. F. Faustino, J. A. S. Cavaleiro, C. Lodeiro, M. I. S. Veríssimo, T. Fernandes, A. L. Daniel-da-Silva, M. T. S. R. Gomes, M. G. P. M. S. Neves N-Confused Porphyrin Immobilized on Solid Supports: Synthesis and Metal Ions Sensing Efficacy Molecules 2018, 23(4), 867 DOI:10.3390/molecules23040867
64. M. António, J. Nogueira, R. Vitorino, A. L. Daniel-da-Silva Functionalized Gold Nanoparticles for the Detection of C-Reactive Protein Nanomaterials 2018, 8, 200 (REVIEW) DOI:10.3390/nano8040200
63. P. Pinheiro, A. L. Daniel-da-Silva, H. Nogueira, T. Trindade Functionalized inorganic nanoparticles for magnetic separation and SERS detection of water pollutants European Journal of Inorganic Chemistry 2018, 3443-3461 DOI:10.1002/ejic.201800132
62. R. Azevedo, J. Soares, C. Gaiteiro, A. Peixoto, L. Lima, D. Ferreira, M. Relvas-Santos, E. Fernandes, A. Tavares, S. Cotton, A. L. Daniel-da-Silva, L. Lara Santos, R. Vitorino, F. Amado, J. A. Ferreira Glycan affinity magnetic nanoplatforms for urinary glycobiomarkers discovery in bladder cancer Talanta 2018, 184, 347-355 DOI:10.1016/j.talanta.2018.03.028
61. S. F. Soares, M. I. Rodrigues, T. Trindade, A. L. Daniel-da-Silva Chitosan-silica hybrid nanosorbents for oil removal from water Colloids and Surfaces A-Physicochemical and Engineering Aspects, 2017, 532, 305-313 DOI:10.1016/j.colsurfa.2017.04.076
60. S. Fateixa, R. S. Carvalho, A. L. Daniel-da-Silva, H. I. S. Nogueira, T. Trindade Luminescent Carrageenan Hydrogels Containing Lanthanopolyoxometalates. European Journal of Inorganic Chemistry 2017, 43, 4976-4981 DOI: 10.1002/ejic.201700888
59. F. Trindade, P. Bastos, A. Leite-Moreira, B. Manadas, R. Ferreira, S. F. Soares, A. L. Daniel-da-Silva, I. Falcao-Pires, R. Vitorino A fractionation approach applying chelating magnetic nanoparticles to characterize pericardial fluid's proteome Archives of Biochemistry and Biophysics 2017, 634, 1-10 DOI:10.1016/j.abb.2017.09.016
58. F. Trindade, P. Bastos, R. Ferreira, A. Leite-Moreira, I. Falcão-Pires, B. Manadas, A. L. Daniel-da-Silva, R. Vitorino EDTA-functionalized Magnetic Nanoparticles: a suitable platform for the analysis of low abundant urinary proteins Talanta 2017,170, 81-88 DOI:10.1016/j.talanta.2017.03.087
57. C.C. Fortes, A. L. Daniel-da-Silva, A. M. R. B. Xavier, A. P. Tavares Optimization of enzyme immobilization on functionalized magnetic nanoparticles for laccase biocatalytic reactions Chemical Engineering & Processing: Process Intensification 2017, 117, 1-8 DOI:10.1016/j.cep.2017.03.009
56. T. Fernandes, S. F. Soares, T. Trindade, A. L. Daniel-da-Silva Magnetic Hybrid Nanosorbents for the Uptake of Paraquat from Water Nanomaterials 2017, 7, 68 DOI: 10.3390/nano7030068
55. V. Bastos, J. M. P. Ferreira de Oliveira, J. Carrola, A. L. Daniel-da-Silva, I. F. Duarte, C. Santos, H. Oliveira Coating independent cytotoxicity of citrate- and PEG-coated silver nanoparticles on a human hepatoma cell line Journal of Environmental Sciences 2017, 51, 191-201 DOI:10.1016/j.jes.2016.05.028
54. A. R. Fernandes, A. P. Tavares, A. L. Daniel-da-Silva, A. M. R. B. Xavier EDTA-Cu(II) chelating magnetic nanoparticles as a support for laccase immobilization Chemical Engineering Science 2017, 158, 599-605 DOI:10.1016/j.ces.2016.11.011
53. C. Couto, R. Vitorino, A. L. Daniel-da-Silva Gold nanoparticles and bioconjugation: a pathway for proteomic applications Critical Reviews in Biotechnology 2017, 37, 238-250 (REVIEW) DOI:10.3109/07388551.2016.1141392
52. S. F. Soares, T. R. Simões, T. Trindade, A. L. Daniel-da-Silva Highly Efficient Removal of Dye from Water Using Magnetic Carrageenan/Silica Hybrid Nano-adsorbents Water, Air and Soil Pollution 2017, 228, 87 DOI: 10.1007/s11270-017-3281-0
51. D. S. Tavares, C. B. Lopes, A. L. Daniel-da-Silva, C. Vale, T. Trindade, M. E. Pereira Mercury in river, estuarine and seawaters - Is it possible to decrease realist environmental concentrations in order to achieve environmental quality standards? Water Research 2016, 106, 439-449 DOI:10.1016/j.watres.2016.10.031
50. V. Bastos, D. Brown, H. Johnston, A. L. Daniel-da-Silva, I. F. Duarte, C. Santos, H. Oliveira Inflammatory responses of a human keratinocyte cell line to 10 nm citrate- and PEG-coated silver nanoparticles Journal of Nanoparticle Research 2016, 18(7), article 205 DOI:10.1007/s11051-016-3515-x
49. S. F. Soares, T. R. Simões, M. António, T. Trindade, A. L. Daniel-da-Silva Hybrid Nadoadsorbents for the magnetically assisted removal of metoprolol from water Chemical Engineering Journal 2016, 302, 560-569 DOI:10.1016/j.cej.2016.05.079
48. C. Couto, B. Neves, R. Ferreira, A. L. Daniel-da-Silva, R. Vitorino Proteomic studies with a novel nano-magnetic chelating system to capture metalloproteins and its application in the preliminary study of monocyte and macrophage sub-secretome Talanta 2016, 158, 110-117 DOI:10.1016/j.talanta.2016.05.051
47. V. Bastos, J. M. P. Ferreira de Oliveira, D. Brown, H. Jonhston, E. Malheiro, A. L. Daniel-da-Silva, I. F. Duarte, C. Santos, H. Oliveira The influence of Citrate or PEG coating on silver nanoparticle toxicity to a human keratinocyte cell line Toxicology Letters 2016, 249, 29-41 DOI:10.1016/j.toxlet.2016.03.005
46. J. Carrola, V. Bastos, I. Jarak, R. Oliveira-Silva, E. Malheiro, A. L. Daniel-da-Silva, H.Oliveira, C. Santos, A. M. Gil, I. F. Duarte Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure–activity relationships and role of ionic silver and oxidative stress Nanotoxicology 2016, 10(8), 1105-1117 DOI:10.1080/17435390.2016.1177744
45. R. S. Carvalho, A. L. Daniel-da-Silva, T. Trindade Uptake of Europium(III) from water using magnetite nanoparticles Particle and Particle Systems Characterization 2016, 33, 150-157 DOI: 10.1002/ppsc.201500170
44. S. F. Soares, T. Trindade, A. L. Daniel-da-Silva Carrageenan-Silica Hybrid Nanoparticles Prepared by a Non-Emulsion Method European Journal of Inorganic Chemistry 2015, 27, 4588-4594 DOI:10.1002/ejic.201500450
43. A. L. Daniel-da-Silva, A. M. Salgueiro, B. Creaney, R. Oliveira-Silva, N. J. O. Silva, T. Trindade Carrageenan-grafted magnetite nanoparticles as recyclable sorbents for dye removal Journal of Nanoparticle Research 2015, 17, Article 302 DOI: 10.1007/s11051-015-3108-0
42. F. Trindade, F. Amado, R. P. Oliveira-Silva, A. L. Daniel-da-Silva, R. Ferreira, J. Klein, R. Faria-Almeida, P. S. Gomes, R. Vitorino Towards the definition of a Peptidome Signature and Protease Profile in Chronic Periodontitis Proteomics-Clinical Applications 2015, 9, 917-927 DOI: 10.1002/prca.201400191
41. S. Fateixa, S. F. Soares, A. L. Daniel-da-Silva, H. I. S. Nogueira, T. Trindade Silver-gelatine bionanocomposites for qualitative detection of a pesticide by SERS Analyst 2015, 140, 1693-1701 DOI:10.1039/C4AN02105C
40. R. Oliveira-Silva, J. P. Costa, R. Vitorino, A. L. Daniel-da-Silva Magnetic chelating nanoprobes for enrichment and selective recovery of metalloproteases from human saliva Journal Materials Chemistry B 2015, 3, 238-249 DOI:10.1039/C4TB01189A
39. F. M. Silva, R. J. B. Pinto, A. L. Daniel-da-Silva, T. Trindade Cationic release behaviour of antimicrobial cellulose/silver nanocomposites Cellulose 2014, 21(5), 3551-3560 DOI:10.1007/s10570-014-0378-0
38. D.S. Tavares, C.B. Lopes, A.L. Daniel-da-Silva, A.C. Duarte, T. Trindade, E. Pereira The role of operational parameters on the uptake of mercury by dithiocarbamate functionalized particles Chemical Engineering Journal 2014, 254, 559-570 DOI:10.1016/j.cej.2014.06.008
37. J. P. Costa, R. Oliveira-Silva, A. L. Daniel-da-Silva, R. Vitorino Bionanoconjugation for proteomics applications – an overview Biotechnology Advances 2014, 32(5), 952-970 DOI:10.1016/j.biotechadv.2014.04.013
36. S. Fateixa, A. L. Daniel-da-Silva, H. I. S. Nogueira, T. Trindade Raman signal enhancement dependence on the gel strength of Ag/hydrogels used as SERS substrates The Journal of Physical Chemistry C 2014, 118(19), 10394-10392 DOI:10.1021/jp500301q
35. M. Q. Mesquita, J. C. J. M. D. S. Menezes, S. M. G. Pires, M. G. P. M. S. Neves, M. M. Q. Simões, A. C. Tomé, J. A. S. Cavaleiro, Â. Cunha, A. L. Daniel-da-Silva, A. Almeida, M. A. F. Faustino Pyrrolidine fused chlorin photosensitizer immobilized on solid supports for the photoinactivation of Gram negative bacteria Dyes and Pigments 2014, 110, 123-133 DOI:10.1016/j.dyepig.2014.04.025
34. P. C. Pinheiro, D. S. Tavares, A. L. Daniel-da-Silva, C. B. Lopes, E. Pereira, J. P. Araujo, C.T. Sousa, T. Trindade Ferromagnetic sorbents based on nickel nanowires for efficient uptake of mercury from water ACS Applied Materials & Interfaces 2014, 6(11), 8274-8280 DOI:10.1021/am5010865
33. B. J. M. Leite Ferreira, N. B. Barroca, P. P. Lopes, A. L. Daniel-da-Silva, M. H. V. Fernandes, R. N. Correia Properties of novel PMMA-co-EHA bone cements filled with hydroxyapatite Polymer Composites 2014, 35(4), 759-767 DOI:10.1002/pc.22719
32. P. C. Pinheiro, A. L. Daniel-da-Silva, D. S. Tavares, M. P. Calatayud, G. F. Goya, T. Trindade Fluorescent Magnetic Bioprobes by Surface Modification of Magnetite Nanoparticles Materials 2013, 6, 3213-3225 DOI:10.3390/ma6083213
31. A. M. Salgueiro, A. L. Daniel-da-Silva, A. V. Girao, P. C. Pinheiro, T. Trindade Unusual dye adsorption behavior of k-carrageenan coated superparamagnetic nanoparticles Chemical Engineering Journal 2013, 229, 276-284 DOI:10.1016/j.cej.2013.06.015
30. S. Fateixa, A. L. Daniel-da-Silva, N. Jordão, A. Barros-Timmons, T. Trindade, Effect of colloidal silver and gold nanoparticles on the thermal behavior of poly(t-butyl acrylate) composites Colloids and Surfaces A, Physicochemical and Engineering Aspects 2013, 436, 231-236 DOI:10.1016/j.colsurfa.2013.06.009
29. C. B. Lopes , P. Figueira, D. S. Tavares, Z. Lin, A. L. Daniel-da-Silva, A. C. Duarte, J. Rocha, T. Trindade, E. Pereira Core-shell magnetite-silica dithiocarbamate-derivatised particles achieve the Water Framework Directive quality criteria for mercury in surface waters Environmental Science and Pollution Research 2013, 20, 5963-5974 DOI:10.1007/s11356-013-1615-z
28. A. C. Estrada, A. L. Daniel-da-Silva, T. Trindade Photothermally enhanced drug release by k-carrageenan hydrogels reinforced with multiwalled carbon nanotubes RSC Advances 2013, 3, 10828-10836 DOI:10.1039/C3RA40662H
27. D. S. Tavares, A. L. Daniel-da-Silva, C. B. Lopes, N. J. O. Silva, V. S. Amaral, J. Rocha, E. Pereira, T. Trindade Efficient sorbents based on magnetite coated with siliceous hybrid shells for removal of mercury ions Journal Materials Chemistry A 2013, 1, 8134-8143 DOI: 10.1039/C3TA10914C
26. A. L. Daniel-da-Silva, R. S. Carvalho, T. Trindade Magnetic Hydrogel Nanocomposites and Composite Nanoparticles – a Review of Recent Patented Works Recent Patents on Nanotechnology 2013, 7, 153 – 166 DOI:10.2174/18722105113079990008
25. A .M. Salgueiro, A. L. Daniel-da-Silva, S. Fateixa,T. Trindade k-carrageenan hydrogel nanocomposites with release behavior mediated by morphological distinct Au nanofiller Carbohydrate Polymers 2013, 91, 100-109 DOI:10.1016/j.carbpol.2012.08.004
24. J. F. B. Barata, A. L. Daniel-da-Silva, M. G. P. M .S. Neves, J. A. S. Cavaleiro, T. Trindade Corrole-silica hybrid particles: synthesis and effects on singlet oxygen generation RSC Advances 2013, 3, 274-280 DOI: 10.1039/C2RA22133K
23. A. L. Daniel-da-Silva, A. M. Salgueiro, T. Trindade Effects of Au nanoparticles on thermoresponsive genipin-crosslinked gelatin hydrogels Gold Bulletin 2013, 46, 25-33 DOI:10.1007/s13404-012-0078-1
22. N. B. Barroca, A. L. Daniel-da-Silva, P. S.Gomes, M.H.R. Fernandes, S. Lanceros-Mendez, P. Sharma, A. Gruverman, M.H.V. Fernandes, P. M. Vilarinho Suitability of PLLA as piezoelectric substrates for tissue engineering evidenced by microscopy techniques Microscopy and Microanalysis 2012, 18 (suppl 5), 63-64 DOI:10.1017/S1431927612012974
21. A. L. Daniel-da-Silva, J. Moreira, R. Neto, A. C. Estrada, A. M. Gil, T. Trindade Impact of magnetic nanofillers in the swelling and release properties of k-carrageenan hydrogel nanocomposites Carbohydrate Polymers 2012, 87, 328-335 DOI:10.1016/j.carbpol.2011.07.051
20. J.A. Ferreira, A.L. Daniel-da-Silva, R.M.P. Alves, D.S. Duarte, I. Vieira, R. Ferreira, L. Lara Santos, R. Vitorino, F. Amado Synthesis and optimization of lectin functionalized nanoprobes for the selective recovery of glycoproteins from human body fluids Analytical Chemistry 2011, 83, 7035-7043 DOI:10.1021/ac200916j
19. P. Figueira, C. B. Lopes, A. L. Daniel-da-Silva, E. Pereira, A. C. Duarte, T. Trindade Removal of mercury (II) by dithiocarbamate surface functionalized magnetite particles: application to synthetic and natural spiked waters Water Research 2011, 45, 5773-5784 DOI:10.1016/j.watres.2011.08.057
18. A. L. Daniel-da-Silva, L. Ferreira, A. M. Gil, T. Trindade Synthesis and swelling behavior of temperature responsive k-carrageenan nanogels Journal of Colloid and Interface Science 2011, 355, 512-517 DOI:10.1016/j.jcis.2010.12.071
17. N. Barroca, P. M. Vilarinho, A. L. Daniel-da-Silva, A. Wu, M.H.V. Fernandes, A. Gruverman Protein Adsorption on Piezoelectric Poly (L-lactic) acid thin films by scanning probe microscopy Applied Physics Letters 2011, 98, 133705 DOI:10.1063/1.3555444
16. K. B. Sidhpuria, A. L. Daniel-da-Silva, T. Trindade, J. A. P. Coutinho Supported ionic liquid silica nanoparticles (SILnPs) as an efficient and recyclable heterogeneous catalyst for the dehydration of fructose to 5-hydroxymethylfurfural Green Chemistry 2011, 13, 340-349 DOI: 10.1039/C0GC00690D
15. N. B. Barroca, A. L. Daniel-da-Silva, P. M. Vilarinho, M. H. V. Fernandes Tailoring the morphology of high molecular weight PLLA scaffolds through bioglass additions Acta Biomaterialia 2010, 6, 3611-3620 DOI:10.1016/j.actbio.2010.03.032
14. P. I. Girginova, A. L. Daniel-da-Silva, C. Lopes, P. Figueira, M. Ortero, V. S. Amaral, E. Pereira, T. Trindade Silica coated magnetite nanoparticles for magnetic removal of Hg2+ from water Journal of Colloid and Interface Science 2010, 345(2), 234-240 DOI:10.1016/j.jcis.2010.01.087
13. A. L. Daniel-da-Silva, S. Fateixa, A. J. Guiomar, B. F. O. Costa, N. J. O. Silva, T. Trindade, B. J. Goodfellow, A. M. Gil Biofunctionalized magnetic hydrogel nanospheres of magnetite and kappa-carrageenan Nanotechnology 2009, 20, 355602, 1-10 DOI:10.1088/0957-4484/20/35/355602
12. N. B. Barroca, A. L. Daniel-da-Silva, M. H. V. Fernandes, P. M. Vilarinho Porogen effect of bioactive glass on poly(L-lactide) scaffolds: evidences by electron microscopy Microscopy and Microanalysis 2008, 14 (S3) 65-66 DOI:10.1017/S143192760808940X
11. A. L. Daniel-da-Silva, R. Lóio, J. A. Lopes-da-Silva, T. Trindade, B. J. Goodfellow, A. M. Gil Effects of magnetite nanoparticles on the thermo-rheological properties of carrageenan hydrogels Journal of Colloid and Interface Science 2008, 324 (1-2), 205-211 DOI:10.1016/j.jcis.2008.04.051
10. A.L. Daniel-da-Silva, A.M. Gil, R. N. Correia Production of bioactive nano-hydroxyapatite/polysaccharide composites for bone tissue engineering Materials Science Forum 2008, 587-588, 22-26 DOI:10.4028/www.scientific.net/MSF.587-588.22
9. A.L. Daniel-da-Silva, F. Pinto, J.A. Lopes-da-Silva, T. Trindade, B.J. Goodfellow, A.M. Gil Rheological behaviour of thermoreversible k-carrageenan/nanosilica gels Journal of Colloid and Interface Science 2008, 320, 575-581 DOI:10.1016/j.jcis.2008.01.035
8. A.L. Daniel-da-Silva, J.C. Bordado, J.M. Martín-Martínez Moisture curing kinetics of isocyanate ended urethane quasi-prepolymers monitored by IR spectroscopy and DSC Journal of Applied Polymer Science 2008, 107(2), 700-709 DOI:10.1002/app.26453
7. A.L.D. Silva, J.M. Martín-Martínez, J.C.M. Bordado Influence of the storage of reactive urethane quasi-prepolymers in their composition and adhesion properties International Journal of Adhesion and Adhesives 2008, 28, 29-37 DOI:10.1016/j.ijadhadh.2007.03.002
6. A.L. Daniel-da-Silva, J. C. Bordado, J.M. Martín-Martínez Evidences of phase separation in moisture cured poly(urethane)ureas by means of temperature modulated differential scanning calorimetry Journal of Polymer Science Part B: Polymer Physics 2007, 45(22), 3034-3045 DOI:10.1002/polb.21298
5. A.L. Daniel-da-Silva, T. Trindade, B.J. Goodfellow, B.F.O. Costa, R.N. Correia, A.M. Gil In situ synthesis of magnetite nanoparticles in carrageenan gels Biomacromolecules 2007, 8(8), 2350-2357 DOI: 10.1021/bm070096q
4. A.L. Daniel-da-Silva, A.B. Lopes, A.M. Gil, R.N. Correia Synthesis and characterization of porous k-carrageenan/calcium phosphate nanocomposites scaffolds Journal of Materials Science 2007, 42(20), 8581-8591 DOI:10.1007/s10853-007-1851-z
3. A.L. Daniel-da-Silva, J.C.M. Bordado, J.M. Martín-Martínez Use of isoconversional methods to analyze the cure kinetics of isocyanate ended quasi-prepolymers with water Journal of Applied Polymer Science 2007, 104(2), 1049-1057 DOI:10.1002/app.24914
2. A.L.D. da Silva, J.C.M. Bordado, J.M. Martín-Martínez Influence of the free isocyanate content in the adhesive properties of reactive trifunctional polyether urethane quasi-prepolymers International Journal of Adhesion and Adhesives 2006, 26(5), 355-362 DOI:10.1016/j.ijadhadh.2005.06.001
1. A. L. Silva, J.C. Bordado Recent Developments in Polyurethane Catalysis: Catalytic Mechanisms Review Catalysis Reviews. Science and Engineering 2004, 46-1, 31-51 DOI:10.1081/CR-120027049
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Referee of SCI journals
ACS Applied Materials & Interfaces, ACS Applied Nano Materials, ACS Omega, Biomacromolecules, Biomaterials, Carbohydrate Polymers, Industrial & Engineering Chemistry Research, International Journal of Biological Macromolecules, Journal of Colloid and Interface Science, Journal of Physics and Chemistry of Solids, Nanotechnology, NPG Asia Materials, RSC Advances, Separation and Purification Technology, Water Science and Technology
Verified Peer Review Record at the Publons Platform: https://publons.com/author/897314/ana-l-daniel-da-silva
Evaluation of projects/proposals
-European: Future and Emerging Technologies (FET-OPEN-RIA)
-National: ANI-Agência Nacional de Inovação
Editorial Activities
-Molecules–Member of Editorial Board (2018-)
-Nanomaterials–Guest Editor Special Issue “Green Nanotechnologies for Water Remediation Processes”(2018)
-Nanocomposite particles for bio-applications,Pan Stanford,2011 (book)
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The role of operational parameters on the uptake of mercury by dithiocarbamate functionalized particlesTavares, DS; Lopes, CB; Daniel-da-Silva, AL; Duarte, AC; Trindade, T; Pereira, E 2014, CHEMICAL ENGINEERING JOURNAL, 254, 559-570.
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kappa-Carrageenan hydrogel nanocomposites with release behavior mediated by morphological distinct Au nanofillersSalgueiro, AM; Daniel-da-Silva, AL; Fateixa, S; Trindade, T 2013, CARBOHYDRATE POLYMERS, 91, 1, 100-109.
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Core-shell magnetite-silica dithiocarbamate-derivatised particles achieve the Water Framework Directive quality criteria for mercury in surface watersLopes, CB; Figueira, P; Tavares, DS; Lin, Z; Daniel-da-Silva, AL; Duarte, AC; Rocha, J; Trindade, T; Pereira, E 2013, ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 20, 9, 5963-5974.
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Efficient sorbents based on magnetite coated with siliceous hybrid shells for removal of mercury ionsTavares, DS; Daniel-da-Silva, AL; Lopes, CB; Silva, NJO; Amaral, VS; Rocha, J; Pereira, E; Trindade, T 2013, JOURNAL OF MATERIALS CHEMISTRY A, 1, 28, 8134-8143.
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Photothermally enhanced drug release by kappa-carrageenan hydrogels reinforced with multi-walled carbon nanotubesEstrada, AC; Daniel-da-Silva, AL; Trindade, T 2013, RSC ADVANCES, 3, 27, 10828-10836.
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Effects of Au nanoparticles on thermoresponsive genipin-crosslinked gelatin hydrogelsDaniel-da-Silva, AL; Salgueiro, AM; Trindade, T 2013, GOLD BULLETIN, 46, 1, 25-33.
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Corrole-silica hybrid particles: synthesis and effects on singlet oxygen generationBarata, JFB; Daniel-Da-Silva, AL; Neves, MGPMS; Cavaleiro, JAS; Trindade, T 2013, RSC ADVANCES, 3, 1, 274-280.
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Unusual dye adsorption behavior of kappa-carrageenan coated superparamagnetic nanoparticlesSalgueiro, AM; Daniel-da-Silva, AL; Girao, AV; Pinheiro, PC; Trindade, T 2013, CHEMICAL ENGINEERING JOURNAL, 229, 276-284.
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Fluorescent Magnetic Bioprobes by Surface Modification of Magnetite NanoparticlesPinheiro, PC; Daniel-da-Silva, AL; Tavares, DS; Calatayud, MP; Goya, GF; Trindade, T 2013, MATERIALS, 6, 8, 3213-3225.
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Effect of colloidal silver and gold nanoparticles on the thermal behavior of poly(t-butyl acrylate) compositesFateixa, S; Daniel-da-Silva, AL; Jordao, N; Barros-Timmons, A; Trindade, T 2013, COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 436, 231-236.
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Magnetic Hydrogel Nanocomposites and Composite Nanoparticles - a Review of Recent Patented WorksDaniel-da-Silva, AL; Carvalho, RS; Trindade, T 2013, RECENT PATENTS ON NANOTECHNOLOGY, 7, 2, 153-166.
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Impact of magnetic nanofillers in the swelling and release properties of kappa-carrageenan hydrogel nanocompositesDaniel-da-Silva, AL; Moreira, J; Neto, R; Estrada, AC; Gil, AM; Trindade, T 2012, CARBOHYDRATE POLYMERS, 87, 1, 328-335.
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Suitability of PLLA as piezoelectric substrates for tissue engineering evidenced by microscopy techniquesBarroca, NB; Daniel-da-Silva, AL; Gomes, PS; Fernandes, MHR; Lanceros-Mendez, S; Sharma, P; Gruverman, A; Fernandes, MHV; Vilarinho, PM 2012, MICROSCOPY AND MICROANALYSIS, 18, 63-64.
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Swelling and Release Properties of Functional kappa-carrageenan Hydrogel Nanocompositesda Silva, ALD; Salgueiro, AM; Fateixa, S; Moreira, J; Estrada, AC; Gil, AM; Trindade, T 2012, MULTIFUNCTIONAL POLYMER-BASED MATERIALS, 1403, 213-219.
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Synthesis and swelling behavior of temperature responsive kappa-carrageenan nanogelsDaniel-da-Silva, AL; Ferreira, L; Gil, AM; Trindade, T 2011, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 355, 2, 512-517.
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Magnetic and Plasmonic Nanoparticles for Brain Drug DeliveryAna L. Daniel-da-Silva In Carla Vitorino, Andreia Jorge, Alberto Pais (Eds.), Nanoparticles for Brain Drug Delivery 2021, Jenny Stanford Publishing.
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Surface Engineered Magnetic Biosorbents for Water TreatmentSoares S.F., Fernandes T., Trindade T., Daniel-da-Silva A.L. In Crini G., Lichtfouse E. (Eds.), Green Adsorbents for Pollutant Removal 2018, 301-342. Springer.
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Application of Chitosan Based Materials for Drug DeliveryPoliana P Lopes, Nathalie B Barroca, Ana Luísa Daniel-da-Silva, Bárbara J Leite Ferreira In Guilherme Luiz Dotto, Sergio Paulo Campana-Filho and Luiz Antonio de Almeida Pinto (Eds.), Frontiers in Biomaterials: Chitosan Based Materials and its Applications 2017, 181-248. Bentham Science Publishers.
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Bionanocomposites for Magnetic Removal of Water PollutantsF. L. Sousa, A. L. Daniel-da-Silva, N. J. O. Silva, T. Trindade In Vijay Kumar Thakur; Manju Kumari Thakur (Eds.), Eco-friendly polymer nanocomposites: chemistry and applications 2015, 279-310. New Delhi: Springer India.
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From nanoparticles to nanocomposites: a brief overviewPereira AS, Daniel-da-Silva AL, Trindade T Nanocomposite particles for bio-applications: materials and biointerfaces 2012, Singapore: Pan Stanford Publishing.
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Biofunctional Composites of Polysaccharides Containing Inorganic NanoparticlesDaniel-da-Silva AL, Trindade T Advances in Nanocomposite Technology 2011, Rijeka: InTech.
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From Nanoparticles to Nanocomposites: An OverviewAS Pereira, AL Daniel da Silva, T Trindade In T Trindade, AL Daniel da Silva (Eds.), Nanocomposite Particles for Bio-Applications - Materials and Bio-Interfaces 2011, Pan Stanford Publishing.
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