Researcher ID : http://www.researcherid.com/rid/E-4549-2013
Carmen Freire was born in 1976 in Venezuela. In 1994 she concluded high school at Escola Secundária José Estevão (Aveiro), and, motivated by an enormous interest in Chemistry, started her graduation in Industrial Chemistry at the University of Aveiro (UA).
After concluding her graduation in 1998, she started her PhD work, “Eucalyptus globulus Low Molecular Weight Organic Compounds: Behavior During Wood Kraft Pulping and Pulp Bleaching”, at the Chemistry Department of the University of Aveiro. In early 2003, she embraced a post-doctoral project on “Surface Chemical Modification of Cellulose Fibers for Novel Paper and Composite Materials”, developed jointly between the Department of Chemistry of UA and the EFPG (presently Pagora), Institut Polytechnique de Grenoble a forefront research group in the domain of Macromolecular Materials from Renewable Resources. During this period, she got a solid background and knowledge on the development and characterization of natural polymers-based materials.
Since 2006, as a Auxiliary Reseracher (from January 2006 to June 2011) and now as a Principal Researcher (FCT Researcher), she has leaded the research on materials and composites from cellulose and other polysaccharides within BioPol4Fun group at CICECO/UA .
Main achievements:
- 164 articles in SCI journals (December 2018).
- 3 National patents and 2 European patent.
- More than 170 communications in International Conferences
- Referee for several high impact factor international journals in the areas of biomacromolecules, polysaccharides, green and sustainable chemistry and materials in general
- Concluded the supervision of 3 PhD, 3 Post-Docs, 31 Master theses,
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Her research interests are centred on the Chemistry of polymers from renewable resources (caracterization and application) and development of new sustainable composite materials and nanostructured materails for disntinct appications
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BioPol4Fun- Innovation in biopolymeric functional materials and bioactive compounds
Supervisor or co-supervisor of 5 Pos-doctorate students, 10 PhD student and 4 Master students.
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Armando Silvestre, Ana Barros-Timmons, Mara Freire, João Coutinho,Graça Neves, Paulo Claro, Iola Duarte e Filipe Figueiredo (Department of Chemistry, University of Aveiro),
Adelaide Almeida, Helena Oliveira (Department of Biology, University of Aveiro)
Paula Alexandrina Marques (TEMA, University of Aveiro)
Isabel Marrucho (IST)
Fátima Duarte (CEBAL, Beja)
Catarina Rosado (Universidade Lusófona, Lisboa)
Isabel Almeida e Paulo Costa (Faculty of Pharmacy, University of Porto)
Fernando Dourado e Miguel Gama (University of Minho)
Stefan Spirk (TU Graz, Austria)
Hélder Santos (University of Helsinki, Finland)
Pedro Fardim (Abo Akademi, Finland and University of Leuven, Belgium)
Ana Alonsa Varona (UPV, San Sebastian)
Patrizia Sadocco (SSCCP, Stazione Sperimentale Carta, Cartoni e Paste per Carta, Italy)
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Nuno H.C.S. Silva, Carla Vilela, Adelaide Almeida, Isabel M. Marrucho, Carmen S.R.Freire, Pullulan-based nanocomposite films for functional food packaging: Exploiting lysozyme nanofibers as antibacterial and antioxidant reinforcing additives, Food Hydrocolloids, 2018, 77, 921-930.
Louise Saidi, Carla Vilela, Helena Oliveira, Armando J.D. Silvestre, Carmen S.R. Freire, “Poly(N-methacryloyl glycine)/nanocellulose composites: pH-sensitive systems for controlled release of diclofenac”, Carbohydr. Polym., 2017, 169, 357-365.
Carla Vilela, Ricardo J. B. Pinto, Joel Coelho, M. R. M. Domingues, Sara Daina, Patrizia Sadocco, Sónia A. O. Santos, Carmen S. R. Freire, Bioactive chitosan/ellagic acid films with UV-light protection for active food packaging, Food Hydrocolloids, 2017, 73, 120-128.
Joana F.B. Barata, Ricardo J.B. Pinto, Vanda I.R.C. Vaz Serra, Armando J.D. Silvestre, Tito Trindade, Maria Graça P.M.S. Neves, José A.S. Cavaleiro, Sara Daina, Patrizia Sadocco, Carmen S.R. Freire, “Fluorescent bioactive corrole grafted-chitosan films”, Biomacromolecules, 2016, 17, 1395-1403.
Liliana C. Tomé, Ricardo J. B. Pinto, Eliane Trovatti, Carmen S. R. Freire, Armando J. D. Silvestre, Carlos Pascoal Neto, Alessandro Gandini, Transparent bionanocomposites with improved properties prepared from acetylated bacterial cellulose and poly(lactic acid) through a simple approach, Green Chem., 2011, 13, 419-427
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“NanoBioinks- Engineering bio-based nanofibers for the development of high performance bioinks for 3D bioprinting”, CENTRO-01-0145-FEDER-031289, FCT/MCTES, (PI), 2018- “CORLUTNA- Systems based on corrolic macrocycles for luminescent thermometry at nanoscale”, Projeto nº 031523 com o apoio financeiro da Fundação para a Ciência e Tecnologia/MCTES, (co-PI) 2018- “InPaCTus- Products and Technologies from eucalipt”, RCI, I&DANI/AICEP, coordinated by Navigator Company, (PI of 3 sub-projects)
“MultiBiorefinery – Estratégias multiuso para a valorização de uma gama alargada de subprodutos agroflorestais e das pescas: Um passo em frente na criação de uma biorrefinaria integrada” (POCI-01-0145-FEDER-016403), (team member) “AgroForWealth – Biorefinery of agro-forest residues: a strategy for the valorization of resources for wealth and sustainability“; CCDRC (team member)
“INNOVATE- Implantable organic Devices for advanced therapies”, University of Algarve, University of Aveiro, PTDC/EEI-AUT/5442/2014, (PI at UA)
“DeepBiorefinery: "Natural Deep eutectic solvents: a platform to boost Eucalyptus globulus and Quercus suber cork integrated biorrefinery”, Universidade de Aveiro e ITQB. PTDC/AGR-TEC/1191/2014 (team member)
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Enhanced Conversion of Xylan into Furfural using Acidic Deep Eutectic Solvents with Dual Solvent and Catalyst BehaviorMorais, ES; Freire, MG; Freire, CSR; Coutinho, JAP; Silvestre, AJD 2020, CHEMSUSCHEM, 13, 4, 784-790.
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Extraction of High Value Triterpenic Acids from Eucalyptus globulus Biomass Using Hydrophobic Deep Eutectic SolventsSilva, NHCS; Morais, ES; Freire, CSR; Freire, MG; Silvestre, AJD 2020, MOLECULES, 25, 1,
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Multifunctional hybrid structures made of open-cell aluminum foam impregnated with cellulose/graphene nanocompositesPinto, SC; Silva, NHCS; Pinto, RJB; Freire, CSR; Duarte, I; Vicente, R; Vesenjak, M; Marques, PAAP 2020, CARBOHYDRATE POLYMERS, 238,
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Resistive switching of silicon-silver thin film devices in flexible substratesDias, C; Leitao, DC; Freire, CSR; Gomes, HL; Cardoso, S; Ventura, J 2020, NANOTECHNOLOGY, 31, 13,
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Flexible Nanocellulose/Lignosulfonates Ion-Conducting Separators for Polymer Electrolyte Fuel CellsVilela, C; Morais, JD; Silva, ACQ; Munoz-Gil, D; Figueiredo, FML; Silvestre, AJD; Freire, CSR 2020, NANOMATERIALS, 10, 9,
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Swellable Gelatin Methacryloyl Microneedles for Extraction of Interstitial Skin Fluid toward Minimally Invasive Monitoring of UreaFonseca, DFS; Costa, PC; Almeida, IF; Dias-Pereira, P; Correia-Sa, I; Bastos, V; Oliveira, H; Vilela, C; Silvestre, AJD; Freire, CSR 2020, MACROMOLECULAR BIOSCIENCE, 20, 10,
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Highly Electroconductive Nanopapers Based on Nanocellulose and Copper Nanowires: A New Generation of Flexible and Sustainable Electrical MaterialsPinto, RJB; Martins, MA; Lucas, JMF; Vilela, C; Sales, AJM; Costa, LC; Marques, PAAP; Freire, CSR 2020, ACS APPLIED MATERIALS & INTERFACES, 12, 30, 34208-34216.
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The Role of Ionic Liquids in the Pharmaceutical Field: An Overview of Relevant ApplicationsPedro, SN; Freire, CSR; Silvestre, AJD; Freire, MG 2020, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21, 21,
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Use of Ionic Liquids and Deep Eutectic Solvents in Polysaccharides Dissolution and Extraction Processes towards Sustainable Biomass ValorizationMorais, ES; Lopes, AMD; Freire, MG; Freire, CSR; Coutinho, JAP; Silvestre, AJD 2020, MOLECULES, 25, 16,
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Grafting Poly(Methyl Methacrylate) (PMMA) from Cork via Atom Transfer Radical Polymerization (ATRP) towards Higher Quality of Three-Dimensional (3D) Printed PMMA/Cork-g-PMMA MaterialsLacerda, PSS; Gama, N; Freire, CSR; Silvestre, AJD; Barros-Timmons, A 2020, POLYMERS, 12, 9,
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Antibacterial Multi-Layered Nanocellulose-Based Patches Loaded with Dexpanthenol for Wound Healing ApplicationsDaniela F. S. Fonseca, João P. F. Carvalho, Verónica Bastos, Helena Oliveira, Catarina Moreirinha, Adelaide Almeida, Armando J. D. Silvestre, Carla Vilela, Carmen S. R. Freire 2020, Nanomaterials, 10, 12, 2469
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Valorisation of bark lipophilic fractions from three Portuguese Salix species: A systematic study of the chemical composition and inhibitory activity on Escherichia coliRamos, PAB; Moreirinha, C; Santos, SAO; Almeida, A; Freire, CSR; Silva, AMS; Silvestre, AJD 2019, INDUSTRIAL CROPS AND PRODUCTS, 132, 245-252.
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Biosynthesis and bioactivity of Cynara cardunculus L. guaianolides and hydroxycinnamic acids: a genomic, biochemical and health-promoting perspectiveRamos, PAB; Ferro, AM; Oliveira, MM; Goncalves, S; Freire, CSR; Silvestre, AJD; Duarte, MF 2019, PHYTOCHEMISTRY REVIEWS, 18, 2, 495-526.
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New Materials Based on Cationic Porphyrins Conjugated to Chitosan or Titanium Dioxide: Synthesis, Characterization and Antimicrobial EfficacyCastro, KADF; Moura, NMM; Figueira, F; Ferreira, RI; Simoes, MMQ; Cavaleiro, JAS; Faustino, MAF; Silvestre, AJD; Freire, CSR; Tome, JPC; Nakagaki, S; Almeida, A; Neves, MGPMS 2019, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20, 10,
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Recent Developments in the Functionalization of Betulinic Acid and Its Natural Analogues: A Route to New Bioactive CompoundsSousa, JLC; Freire, CSR; Silvestre, AJD; Silva, AMS 2019, MOLECULES, 24, 2,
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Advanced Nanocellulose-Based Materials: Production, Properties and ApplicationsC. Vilela; C.S.R. Freire 2022, MDPI.
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Advanced Biopolymer-Based Nanocomposites and Hybrid MaterialsArmando J. D. Silvestre; Carmen S.R. Freire; Carla Vilela 2021, Basel: MDPI.
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Polysaccharide Based Hybrid Materials, Metals and Metal Oxides, Graphene and Carbon NanotubesCarla Vilela, Ricardo J. B. Pinto, Susana Pinto, Paula Marques, Armando J. D. Silvestre, Carmen S. R. Freire 2018, Springer.
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Active packagingCarvalho, João P.F.; Freire, Carmen S.R.; Vilela, Carla In Galanakis, Charis (Eds.), Sustainable Food Processing and Engineering Challenges 2021, Academic Press.
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Modification of textiles for functional applicationsAna C. Q. Silva, Armando J. D. Silvestre, Carmen S. R. Freire, Carla Vilela In Md. Ibrahim H. Mondal (Eds.), Fundamentals of Natural Fibres and Textiles 2021, 303-365. Elsevier.
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Furanoate-Based Nanocomposites: A Case Study Using Poly(Butylene 2,5-Furanoate) and Poly(Butylene 2,5-Furanoate)-co-(Butylene Diglycolate) and Bacterial CelluloseMarina Matos, Andreia Sousa, Nuno H.C.S. silva, Carmen S.R. Freire, Márcia Andrade, Adélio Mnedes, Armando J.D. Silvestre In George Z. Papageorgiou (Eds.), Polymers from Renewable Resources 2018, MDPI.
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Development and applications of cellulose nanofibres based polymer nanocompositesCarla Vilela, Ricardo J. B. Pinto, Ana R. P. Figueiredo, Carlos Pascoal Neto, Armando J. D. Silvestre, Carmen S. R. Freire In Ehsan Bafekrpour (Eds.), Advanced Composite Materials: Properties and Applications 2017, 1-65. Warsaw/Berlin: De Gruyter Open.
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Antimicrobial Properties and Therapeutic Applications of Silver Nanoparticles and NanocompositesR.J.B. Pinto, M. Nasirpour, J. Carrola, H. Oliveira, C.S.R. Freire, I.F. Duarte In Alexandru Mihai Grumezesc (Eds.), Antimicrobial Nanoarchitectonics - From Synthesis to Applications 2017, 223-259. Elsevier.
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Polyethylene Terephthalate: Copolyesters, Composites, and Renewable AlternativesAndreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho In P. M. Visakh Mong Liang (Eds.), Poly(ethylene Terephthalate) Based Blends, Composites and Nanocomposites. 2015, 111-139. Elsevier Science Ltd.
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Recent advances on the development of antibacterial polysaccharide-based materials, Chitosan, cellulose and starchV. Coma, C.S.R. Freire and A.J.D. Silvestre In Ramawat, Kishan Gopal, Mérillon, Jean-Michel (Eds.), Polysaccharides: Bioactivity and Biotechnology 2015, 1751-1803. New York: Springer International Publishing.
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Polyethylene Terephthalate: Copolyesters, Composites, and Renewable AlternativesAndreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho In Visakh P.M., Mong Liang (Eds.), POLY(ETHYLENE TEREPHTHALATE) BASED BLENDS, COMPOSITES AND NANOCOMPOSITES 2015, Elsevier Inc..
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2 Bacterial Cellulose-Based Nanocomposites: Roadmap for Innovative MaterialsA. R. P. Figueiredo, C. Vilela, C. Pascoal Neto, A.J.D. Silvestre and C.S.R. Freire Nanocellulose Polymer Nanocomposites: Fundamentals and Applications 2014, Scrivener: Willey.
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The bulk oxypropylation of chitin and chitosan and the characterization of the ensuing polyolsFernandes S, Freire CSR, Pascoal Neto C, Gandini A In Senel S, Vårum KM Sumnu MM Hincal AA (Eds.), Advances In Chitin Science 2007, 10, 530-535. Antalya:
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Biosorbent films based on nanocellulose and lysozyme nanofibers for efficient removal of mercury (II) from natural watersSilva, N; Figueira, P; Vilela, C; Pinto, R; Marrucho, I; Periera, M; Freire, C 2018, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 255,
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Novel multilayered nanostructured drug delivery systems obtained by layer-by-layer assembly of cellulose nanocrystals Maia. M, Vilela. C, Pinto. R, Valente. B, Carvalho. T, Freire. C 2018,
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Biosorbent films based on nanocellulose and lysozyme nanofibers for efficient removal of mercury (II) from natural watersSilva, N; Figueira, P; Vilela, C; Pinto, R; Marrucho, I; Pereira, M; Freire, C 2018, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 255,
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