Ana Maria Ferreira Takahashi

Junior Researcher

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  • Chemistry
  • 29.1.37

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short cv

I obtained my MSc degree in Chemical Engineering from the University of Aveiro in 2013. In July of 2018, I completed my PhD in Chemical Engineering at the University of Aveiro, funded by Fundação para a Ciência e Tecnologia (FCT) through a PhD scholarship. During the PhD I had the opportunity to broaden my scientific skills abroad, through trainees at Universidade Estadual Paulista, Brazil, and Tokyo University of Agriculture, Japan. After finishing my PhD, I moved to the Technical University of Munich (TUM, one of the world's top universities), Germany, as a postdoctoral researcher, to work on the purification of compounds from microalgae in collaboration with the company Oceanbasis, with a TUM University Foundation Fellowship. This fellowship is awarded once a year by TUM, where ca. 10 young scientists are selected from all over the world. Currently, I am a researcher at UA working in the chiral resolution of drugs by enantioselective aqueous biphasic systems, being the importance of this work recognized in the international conference Biopartitioning & Purification 2019 (BR) with the award for best presentation poster sponsored by Elsevier. Up to the data, I am in 2 funded R&D projects. I am PI of 1 funded project (POCI-01-0145-FEDER-030750, 239893 EUR), and team member in another funded project (POCI-01-0247-FEDER-045304, 297976 EUR) in collaboration with the company Mistolin. Overall, in these last years, I gathered a vast knowledge on the development of sustainable extraction/purification platforms (using both solid- and liquid-liquid extraction) of compounds from different matrices, showing my commitment to science in the benefit of the environment and society.

Since the beginning of my research activities, I filled 1 national patent, published 2 book chapters, 18 SCI papers and 1 journal cover, with 600+ citations and an h-index of 13. I have published in various high IF journals, namely Green Chem (IF 9.48, 8/18 SCI), ACS Sustain Chem Eng (IF 7.63), Chem Commun (IF 5.99), Sep Purif Technol (IF 5.77) and others. I am the first author in 9/18 SCI papers and worked with 43 co-authors. Moreover, I contributed with 90+ communications.

background

2014-2018: PhD in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

2008-2013: MSc in Chemical Engineering, Department of Chemistry, University of Aveiro, Portugal.

research area

Chemical Engineering

Development of innovative, integrated and sustainable processes for the extraction and separation of value-added compounds (alkaloids, amino acids, phenolic acids and others natural compounds) with therapeutic features from biomass, as well as wastes, using aqueous solutions of ionic liquids and surfactants, within a biorefinery perspective (circular economy).

 

Biotechnology

Development of cost-effective purification and recovery processes for several value‐added biopharmaceuticals, namely proteins, enzymes, antibodies, and nucleic‐acids‐based products.

 

Chemistry/Physical Chemistry

Understand the molecular‐level mechanisms which rule the liquid-liquid equilibria and the extraction performance of separation processes, by the determination of thermodynamic properties of solution, solvation and transfer.

Projects

Publications

Using COSMO-RS in the Design of Deep Eutectic Solvents for the Extraction of Antioxidants from Rosemary

Wojeicchowski, JP; Ferreira, AM; Abranches, DO; Mafra, MR; Coutinho, JAP
2020, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 8, 32, 12132-12141.

Recovery of Syringic Acid from Industrial Food Waste with Aqueous Solutions of Ionic Liquids

de Faria, ELP; Ferreira, AM; Claudio, AFM; Coutinho, JAP; Silvestre, AJD; Freire, MG
2019, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 7, 16, 14143-14152.

Continuous separation of cytochrome-c PEGylated conjugates by fast centrifugal partition chromatography

Santos, JHPM; Ferreira, AM; Almeida, MR; Quinteiro, PSGN; Dias, ACRV; Coutinho, JAP; Freire, MG; Rangel-Yagui, CO; Ventura, SPM
2019, GREEN CHEMISTRY, 21, 20, 5501-5506.
ISBN: 1463-9270

Cloud Point Extraction of Chlorophylls from Spinach Leaves Using Aqueous Solutions of Nonionic Surfactants

Leite, AC; Ferreira, AM; Morais, ES; Khan, I; Freire, MG; Coutinho, JAP
2018, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 6, 1, 590-599.

An integrated process for enzymatic catalysis allowing product recovery and enzyme reuse by applying thermoreversible aqueous biphasic systems

Ferreira, AM; Passos, H; Okafuji, A; Tavares, APM; Ohno, H; Freire, MG; Coutinho, JAP
2018, GREEN CHEMISTRY, 20, 6, 1218-1223.

Enhanced separation performance of aqueous biphasic systems formed by carbohydrates and tetraalkylphosphonium- or tetraalkylammonium-based ionic liquids

Quental, MV; Pereira, MM; Ferreira, AM; Pedro, SN; Shahriari, S; Mohamadou, A; Coutinho, JAP; Freire, MG
2018, GREEN CHEMISTRY, 20, 13, 2978-2983.

Designing the thermal behaviour of aqueous biphasic systems composed of ammonium-based zwitterions

Ferreira, AM; Passos, H; Okafuji, A; Freire, MG; Coutinho, JAP; Ohno, H
2017, GREEN CHEMISTRY, 19, 17, 4012-4016.

Enhanced extraction and biological activity of 7-hydroxymatairesinol obtained from Norway spruce knots using aqueous solutions of ionic liquids

Ferreira, AM; Morais, ES; Leite, AC; Mohamadou, A; Holmbom, B; Holmbom, T; Neves, BM; Coutinho, JAP; Freire, MG; Silvestre, AJD
2017, GREEN CHEMISTRY, 19, 11, 2626-2635.

Switchable (pH-driven) aqueous biphasic systems formed by ionic liquids as integrated production-separation platforms

Ferreira, AM; Claudio, AFM; Valega, M; Domingues, FMJ; Silvestre, AJD; Rogers, RD; Coutinho, JAP; Freire, MG
2017, GREEN CHEMISTRY, 19, 12, 2768-2773.

Are Aqueous Biphasic Systems Composed of Deep Eutectic Solvents Ternary or Quaternary Systems?

Passos, H; Tavares, DJP; Ferreira, AM; Freire, MG; Coutinho, JAP
2016, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 4, 5, 2881-2886.

Anti-Cancer Biosurfactants

In Springer (Eds.), Microbial Biosurfactants
Flávia F. Magalhães, João C. F. Nunes, Marília T. Araújo, Ana M. Ferreira, Mafalda R. Almeida, Mara G. Freire, Ana P. M. Tavares
2021, 159-196.
ISBN: 10.1007/978-981-15-6607-3_8

Purification, characterization and clinical applications of therapeutic fungal enzymes

In Pankaj Kumar Chaurasia and Shashi Lata Bharati (Eds.), Research Advances in the Fungal World: Culture, Isolation, Identification, Classification, Characterization, Properties and Kinetics
Mafalda R. Almeida, Ana M. Ferreira, João C. F. Nunes and Ana P. M. Tavares
2020, 273-320, Nova Science Publishers.
ISBN: 978-1-53617-197-6

Ionic Liquids Aqueous Solutions as Sustainable Solvents in Separation Processes

Ana Maria da Conceição Ferreira
2018, supervised by Mara G. Freire and João A. P. Coutinho.

Separation of dyes with reversible aqueous biphasic systems

Ana Maria da Conceição Ferreira
2013, supervised by Ana M. Fernandes and Mara G. Freire.

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