Ongoing Supervisions
Projects
Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion (TETRISSUE)
PartnerFundação para a Ciência e a Tecnologia
The driving force behind TETRISSUE is inspired in the fundamentals of the native bone regenerative process and supported by a strong technological character to produce highly vascularized ultrastructured bone replacements. Its innovative character is mainly related with the integration of key elements working in tandem: (1) bioinstructive microp...Unlocking the scientific excellence and innovation capacity of the University of Aveiro in supramolecular multicomponent biomaterials for enabling advanced biomaterials for healthcare (SUPRALIFE)

CoordinatorEuropean Comission
The SUPRALIFE project is a Twinning project funded by the European Union’s Horizon Europe research and innovation programme which is coordinated by the COMPASS Research Group at CICECO, at the University of Aveiro (UAVR, Portugal). The consortium also brings together the Eindhoven University of Technology (TU/e, The Netherland...3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair (PROMENADE)
PartnerFundação para a Ciência e a Tecnologia
magnetic; 3D cell colonization; hydrogelDesenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de uma membrana periodontal multicamada composta por blocos inovativos a base de polimeros de origem marinha e enzima para regeneracao guiada de osso que possui mineralizacao enzimatica controlada. (MIMETIc)
PartnerFundação para a Ciência e a Tecnologia
Dispositivos Supramoleculares Auto-Regulados baseados na Complementaridade dos Pares de Base do ADN: Uma Tecnologia Biomimética e com Reconheciemnto Molecular para Isolar Células Específicas para Aplicações Biomédicas (SUPRASORT)
CoordinatorFundação para a Ciência e a Tecnologia
Hidrogéis de Lisados de Plaquetas para Regeneração do Miocárdio (BEAT)
PartnerFundação para a Ciência e a Tecnologia
Marine Origin Biopolymers as Innovative Building Blocks from the Sea for the Development of Bioresorbable Multilayered Membranes for guided bone regeneration (BLUETEETH)
PartnerFundação para a Ciência e a Tecnologia
Natural origin polymers from algae and arthropods can be obtained in large scale, and a great effort has been paid to find applications for such high-added value materials. Periodontal disease is frequent in humans and constitutes, together with dental caries, the principal cause of tooth loss in adults. Currently, one of the available treatment...Metodologias eficientes para a conjugação de polissacarídeos naturais com péptidos para obtenção de membranas multifuncionais para regeneração periodontal. (COP2P)
PartnerFundação para a Ciência e a Tecnologia
Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Regeneração Óssea Orquestrada pela Interação de Células do Sistema Imunitário com Microlaboratórios de Células e Microplataformas Padronizadas (CIRCUS)
PartnerFundação para a Ciência e a Tecnologia
Publications
ENGINEERING MINIATURIZED HIGH-THROUGHPUT FREESTANDING MULTILAYERED MEMBRANES FOR BOTTOM-UP TISSUE ENGINEERING STRATEGIES
Fernandes, E; Lopes, F; Patricio, S; Correia, C; Borges, J; Mano, J
2022, TISSUE ENGINEERING PART A, 28, S450-S450.
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THIN SILICA-BASED MICROSHEETS AS A NEW ENABLING TOOL FOR TISSUE REGENERATION
Correia, TR; Maciel, MM; Patricio, SG; Borges, J; Levkin, PA; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S155-S156.
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Customizable and Regioselective One-Pot N−H Functionalization of DNA Nucleobases to Create a Library of Nucleobase Derivatives for Biomedical Applications
Djenisa H. A. Rocha, Carmen M. Machado, Vera Sousa, Cristiana F. V. Sousa, Vera L. M. Silva, Artur M. S. Silva, João Borges, João F. Mano
2021, European Journal of Organic Chemistry, 4423-4433.
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In vitro biological response of human osteoblasts in 3D chitosan sponges with controlled degree of deacetylation and molecular weight
Sukul, M; Sahariah, P; Lauzon, HL; Borges, J; Masson, M; Mano, JF; Haugen, HJ; Reseland, JE
2021, CARBOHYDRATE POLYMERS, 254.
ISBN:
1879-1344
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Bioinstructive Layer-by-Layer-Coated Customizable 3D Printed Perfusable Microchannels Embedded in Photocrosslinkable Hydrogels for Vascular Tissue Engineering
Sousa, CFV; Saraiva, CA; Correia, TR; Pesqueira, T; Patricio, SG; Rial-Hermida, MI; Borges, J; Mano, JF
2021, BIOMOLECULES, 11, 6.
ISBN:
2218-273X
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Customizable and Regioselective One-Pot N-H Functionalization of DNA Nucleobases to Create a Library of Nucleobase Derivatives for Biomedical Applications
Rocha, DHA; Machado, CM; Sousa, V; Sousa, CFV; Silva, VLM; Silva, AMS; Borges, J; Mano, JF
2021, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 31, 4423-4433.
ISBN:
1099-0690
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Supramolecular dendrimer-containing layer-by-layer nanoassemblies for bioapplications: current status and future prospects
Cristiana F. V. Sousa, Eduardo Fernandez-Megia, João Borges, João F. Mano
2021, Polymer Chemistry, 12, 5902-5930.
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Advanced Bottom-Up Engineering of Living Architectures
Gaspar, VM; Lavrador, P; Borges, J; Oliveira, MB; Mano, JF
2020, ADVANCED MATERIALS, 32, 6.
ISBN:
1521-4095
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Enzymatically degradable, starch-based layer-by-layer films: application to cytocompatible single-cell nanoencapsulation
Moon, HC; Han, S; Borges, J; Pesqueira, T; Choi, H; Han, SY; Cho, H; Park, JH; Mano, JF; Choi, IS
2020, SOFT MATTER, 16, 26, 6063-6071.
ISBN:
1744-6848
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Thin Silica-Based Microsheets with Controlled Geometry
Maciel, MM; Patricio, SG; Borges, J; Levkin, PA; Correia, TR; Mano, JF
2020, EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2020, 17, 1574-1578.
ISBN:
1099-0682
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Extending the Functionality of Marine-origin Polysaccharides Through Chemical Modification for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
João M. M. Rodrigues, Edgar J. Castanheira, Dora C. S. Costa, Djenisa H. A. Rocha, João Borges and João F. Mano
2021, 180-204, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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Shaping Soft Structures Using Bottom-up Layer-by-layer Assembly Technology for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
João Borges, Cristiana F. V. Sousa, Isabel M. Bjørge, Sara Nadine, Clara R. Correia, Sónia G. Patrício and João F. Mano
2021, 444-473, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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Stimuli-responsive Nanocomposite Hydrogels Incorporating Soft Nanoparticles for Biomedical Applications

In Helena S. Azevedo, João F. Mano, João Borges (Eds.), Soft Matter for Biomedical Applications
Pedro Lavrador, João Borges, Vítor M. Gaspar and João F. Mano
2021, 566-593, Royal Society of Chemistry (RSC).
ISBN:
978-1-78801-757-2
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