Ongoing Supervisions
Projects
Exploring devitalized MSCs fibres as immunomodulatory devices for wound regeneration through (i) direct promotion of healing or (ii) enabling of allograft transplantation free of systemic immunosuppression (LAZARUS)
CoordinatorOther International
The project aims at exploring MSCs as constituents of off-the-shelf easy-to-handle immunomodulatory biomaterials. The project focuses on using these materials to treat difficult-to-heal wounds, which may be chronic, or have proneness to become chronic if not properly treated.Two treatment approaches will be explored using devitalized MSC aggrega...Hybrid living bioengineered hierarchical constructs with self-oxygenating capability (O2CELLS)
PartnerFundação para a Ciência e a Tecnologia
Tissue engineering (TE) has emerged as an alternative solution aiming to provide a surplus of temporary structural supports at the defect site until native tissue is endogenously regenerated and normal function is restored. Although progresses have been made in the last 20 years, it is not yet possible to address all the complexity and (multi)fu...Innovative tools to treat and model complex cancer environments (TheraTools)

PartnerEuropean Comission
Funded by the Marie Skłodowska-Curie Actions programme, the TheraTools project will create a multidisciplinary research and training network to focus on the technological development of scientific tools to study malignant tumours localised beyond a biological barrier, as in the case of brain tumours. The TheraTools consortium will provi...Merging Sustainable and Digital Chemical Technologies for The Development of Greener-Bydesign Pharmaceuticals (SusPharma)

PartnerEuropean Comission
Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern ...Metabolite-activated 3D stem cell differentiation into bone (BetterBone)
PartnerFundação para a Ciência e a Tecnologia
Strategies involving mesenchymal stem cell (MSC) osteogenic differentiation have emerged as promising tools in regenerative medicine. These work by either promoting in situ regeneration, or through newly-fabricated tissue grafts, potentially overcoming clinical complications related to more conventional therapies. However, bioengineered ...A Metabolomics-guided Bioreactor for Improved Engineered Bone Implants (BioImplant)
PartnerFundação para a Ciência e a Tecnologia
Advancing the Regenerative and Translational Potential of Cellular Fibers (CellFi)
CoordinatorFundação para a Ciência e a Tecnologia
Mesenchymal Stem Cells Scaffold-free Cellular Fibers RegenerationCápsulas esféricas multicompartimentalizadas de alto rendimento para a transplantação de co-culturas multimodais de células estaminais derivadas do tecido adiposo e ilhotas pancreáticas. (TranSphera)
PartnerFundação para a Ciência e a Tecnologia
Desenvolvimento de hidrogeis de inspiracao marinha multifuncionais e de elevado desempenho para regeneracao de cartilagem, reticulados com ligacoes nao-covalentes e bio-instrutivas deslizantes. (MARGEL)
PartnerFundação para a Ciência e a Tecnologia
Development and testing of multifunctional carriers based on micro- and nanoscale engineering for targeted, controlled, and safe delivery of agrochemicals to crops (Agritarget)
PartnerFundação para a Ciência e a Tecnologia
Produção de Plataformas Microcapsulares 3D+ para Avaliação Laboratorial em Larga Escala de Novas Terapias Combinatórias para o Cancro do Pâncreas (PANGEIA)
PartnerFundação para a Ciência e a Tecnologia
Publications
Screening of perfused combinatorial 3D microenvironments for cell culture
Lopes, D; Fernandes, C; Nobrega, JM; Patricio, SG; Oliveira, MB; Mano, JF
2019, ACTA BIOMATERIALIA, 96, 222-236.
ISBN:
1878-7568
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Microparticles in Contact with Cells: From Carriers to Multifunctional Tissue Modulators
Neto, MD; Oliveira, MB; Mano, JF
2019, TRENDS IN BIOTECHNOLOGY, 37, 9, 1011-1028.
ISBN:
1879-3096
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Bone physiology as inspiration for tissue regenerative therapies
Lopes, D; Martins-Cruz, C; Oliveira, MB; Mano, JF
2018, BIOMATERIALS, 185, 240-275.
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Sequentially Moldable and Bondable Four-Dimensional Hydrogels Compatible with Cell Encapsulation
Oliveira, MB; Bastos, HXS; Mano, JF
2018, BIOMACROMOLECULES, 19, 7, 2742-2749.
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Biomimetic click assembled multilayer coatings exhibiting responsive properties
Sousa, MP; de Torre, IG; Oliveira, MB; Rodriguez-Cabello, JC; Mano, JF
2017, MATERIALS TODAY CHEMISTRY, 4, 150-163.
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The influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages
Correia, CR; Gaifem, J; Oliveira, MB; Silvestre, R; Mano, JF
2017, BIOMATERIALS SCIENCE, 5, 3, 551-560.
ISBN:
2047-4849
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Screening of Nanocomposite Scaffolds Arrays Using Superhydrophobic-Wettable Micropatterns
Leite, AJ; Oliveira, MB; Caridade, SG; Mano, JF
2017, ADVANCED FUNCTIONAL MATERIALS, 27, 28.
ISBN:
1616-3028
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Coating Strategies Using Layer-by-layer Deposition for Cell Encapsulation
Oliveira, MB; Hatami, J; Mano, JF
2016, CHEMISTRY-AN ASIAN JOURNAL, 11, 12, 1753-1764.
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Fabrication of Hydrogel Particles of Defined Shapes Using Superhydrophobic-Hydrophilic Micropatterns
Neto, AI; Demir, K; Popova, AA; Oliveira, MB; Mano, JF; Levkin, PA
2016, ADVANCED MATERIALS, 28, 35, 7613-+.
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