Luísa Seuanes Serafim

Assistant Professor

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Department

  • Chemistry
  • 29.1.26

Research

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Short CV

PhD in Biological Engineering, New University of Lisbon (2004).

BSc in Chemical Engineering, Biotechnology, Technical University of Lisbon (1997).

2015- , Assistant Professor, University of Aveiro

2008-2015, Invited Assistant Professor, University of Aveiro

2004-2008, Post Doc Reseacher, New University of Lisbon/FCT

Scientific Interests

Production of biopolymers by mixed cultures and pure cultures: optimization and process control, identification of the microorganisms evolved, polymer characterization, downstream process optimization.
Anaerobic digestion for the production of volatile fatty acids: use of industrial wastes as substrates.
Bioethanol production from wastes by yeast: optimization of process control by controlling the oxygen supply.
Microbial biosurfactant production by strains isolated from contaminated soil.
Bacterial cellulose production from synthetic and real substrates.

Present Research Group

Ana Xavier

Patrícia Domingues (PhD student)

Fernando Sá (MSc Student)

Rita Branco

Main present collaborators

Ana Xavier (CICECO/UA)

Dmitry Evtyugin (CICECO/UA)

Armando Silvestre (CICECO/UA)

Carmen Freire (CICECO/UA)

João Coutinho (CICECO/UA)

Artur Ferreira (CICECO/UA)

Angela Cunha (CESAM/UA)

Isabel Capela (CESAM/UA)

Paulo Lemos (REQUIMTE/FCT-UNL)

Simona Rossetti (IRSA/CNR, Italy)

Simon Bengtsson (AnoxKaldnes, Sweden)

Alan Werker (AnoxKaldnes, Sweden)

Teaching Activity

Vice-Director of BSc. in Biotechnology

Erasmus Coordinator of Biotechnology

Subjects: Biochemical Engineering I and II, Applied Biotechnology

Selected Publications

Advances in ethanol production from hardwood spent sulphite liquors. (2013) Susana R. Pereira, Diogo J. Portugal-Nunes, Dmitry V. Evtuguin, Luísa S. Serafim, Ana M.R.B. Xavier. Process Biochemistry, 48(2) 272-282

Production of bacterial cellulose by Gluconacetobacter sacchari using dry olive mill residue (2013)
Fabio P. Gomes, Nuno H. C.S. Silva, Eliane Trovatti, Luisa S. Serafim, Maria F. Duarte, Armando J.D. Silvestre, Carlos Pascoal Neto, Carmen S.R. Freire, Biomass and Bioenergy, 55, 205-211.

“DESIGN IONIC-LIQUID-BASED AQUEOUS BIPHASIC SYSTEMS WITH CONTROLLED PH: THE IONIC LIQUID ANION EFFECT” (2012). S.P.M. Ventura, S.G. Sousa, M.G. Freire, L.S. Serafim, Á.S. Lima, J.A.P. Coutinho; Journal of Chemical and Engineering Data, 57, 507-512.

“BIOLOGICAL TREATMENT OF EUCALYPT SPENT SULPHITE LIQUORS: A WAY TO BOOST THE PRODUCTION OF SECOND GENERATION BIOETHANOL” (2012). S.R. Pereira, S. Ivanusa, D.V. Evtuguin, L.S. Serafim, A.M.R.B. Xavier; Bioresource Technology, 103, 131-135.

“IONIC LIQUID BASED AQUEOUS BIPHASIC SYSTEMS WITH CONTROLLED PH: THE IONIC LIQUID CATION EFFECT” (2011). S.P.M. Ventura, S.G. Sousa, M.G. Freire, L.S. Serafim, Á.S. Lima, J.A.P. Coutinho; Journal of Chemical and Engineering Data, 56, 4253-4260.

“DESIGN OF IONIC LIQUIDS FOR LIPASE PURIFICATION” (2011). S.P.M. Ventura, S.G. Sousa, M.G. Freire, L.S. Serafim, Á.S. Lima, J.A.P. Coutinho; Journal of Chromatography B, 879, 2679-2687.

“GLUCONACETOBACTER SACCHARI: AN EFFICIENT BACTERIAL CELLULOSE CELL-FACTORY” (2011). E. Trovatti, L.S.Serafim, C.S.R. Freire, A.J.R. Silvestre, C.P. Neto; Carbohydrate Polymers, 86, 1417-1420.

“UTILIZATION OF RESIDUES FROM AGRO-FOREST INDUSTRIES IN THE PRODUCTION OF HIGH VALUE BACTERIAL CELLULOSE” (2011). P. Carreira, J.A.S. Mendes, E. Trovatti, L.S.Serafim, C.S.R. Freire, A.J.R. Silvestre, C.P. Neto; Bioresource Technology, 102, 7354-7360.

“NUCLEAR MAGNETIC RESONANCE STUDY OF THE CHEMICAL COMPOSITION AND MICROSTRUCTURE OF P(3HB-co-3HV) PRODUCED BY MIXED MICROBIAL CULTURES” (2009). G.I. Ivanova; L.S. Serafim; P.C. Lemos; A.M. Ramos; M.AM. Reis; E.J. Cabrita; Magnetic Ressonance in Chemistry 47(6), 497-504

“THE INFLUENCE OF PROCESS PARAMETERS ON THE CHARACTERISTICS OF PHA PRODUCED BY MIXED CULTURES” (2008). L.S. Serafim, P.C. Lemos, C. Torres, M.A.M. Reis, A.M. Ramos; Macromolecular Bioscience 8(4), 355-366.

“MICROBIAL CHARACTERISATION OF POLYHYDROXYALKANOATES STORING POPULATIONS SELECTED UNDER DIFFERENT OPERATING CONDITIONS USING A CELL-SORTING RT-PCR APPROACH” (2008). P.C. Lemos, C. Levantesi, L.S. Serafim, S. Rossetti, M.A.M. Reis, V. Tandoi; Applied Microbiology and Biotechnology 78(2), 351-360.

“METABOLIC MODELLING OF POLYHYDROXYALKANOATES COPOLYMERS PRODUCTION BY MIXED MICROBIAL CULTURES” (2008). J.M.L. Dias, A. Oehmen, L.S. Serafim, P.C. Lemos, M.A.M. Reis, R. Oliveira; BMC Systems Biology 2:59.

“STRATEGIES FOR PHA PRODUCTION BY MIXED CULTURES AND RENEWABLE WASTE MATERIALS” (2008). L.S. Serafim, P.C. Lemos, M.G.E. Albuquerque, M.A.M. Reis; Applied Microbiology and Biotechnology 81(4), 615-628.

“SYNTHESIS OF POLYHYDROXYALKANOATES FROM DIFFERENT SHORT-CHAIN FATTY ACIDS BY MIXED CULTURES SUBMITTED TO AEROBIC DYNAMIC FEEDING” (2006). P.C. Lemos, L.S. Serafim, M.A.M. Reis, Journal of Biotechnology 122(2), 226-238.

“MICROBIAL COMMUNITY ANALYSIS WITH A HIGH PHA STORAGE CAPACITY ” (2006). L.S. Serafim, P.C. Lemos, S. Rossetti, C. Levantesi, V. Tandoi, M.A.M. Reis; Water Science and Technology 54(1), 183-188.

“RECENT ADVANCES IN POLYHYDROXYALKANOATE PRODUCTION BY MIXED AEROBIC CULTURES: FROM THE SUSBTRATE TO THE FINAL PRODUCT” (2006). J.M.L. Dias, P.C. Lemos, L.S. Serafim, C. Oliveira, M. Eiroa, M.G.E. Albuquerque, A.M. Ramos, R. Oliveira, M.A.M. Reis; Macromolecular Bioscience 6(11), 885-906.


“ MATHEMATICAL MODELLING OF A MIXED CULTURE CULTIVATION PROCESS FOR THE PRODUCTION OF POLYHYDROXYBUTYRATE” (2005). J.M.L. Dias, L.S. Serafim, P.C. Lemos, M.A.M. Reis, R. Oliveira, Biotechnology Bioengineering 92(2), 209-222. 

“OPTIMISATION OF POLYHYDROXYBUTYRATE PRODUCTION BY MIXED CULTURES SUBMITTED TO AEROBIC DYNAMIC FEEDING CONDITIONS” (2004). L.S. Serafim, P.C. Lemos, R. Oliveira, M.A.M. Reis Biotechnology Bioengineering, 86(2), 145-160.

“POLYHYDROXYALKANOATES PRODUCTION BY ACTIVATED SLUDGE IN A SBR USING ACETATE AND PROPIONATE AS CARBON SOURCES” (2004). P.C. Lemos, L.S. Serafim, M.A.M. Reis, Water Science and Technology 50(10), 189-194.

“METABOLIC PATHWAY FOR PROPIONATE UTILISATION BY PHOSPHORUS ACCUMULATING ORGANISMS IN ACTIVATED SLUDGE: 13C-LABELLING AND IN VIVO NMR” (2003). P.C. Lemos, L.S. Serafim, M.M. Santos, M.A.M. Reis, H.Santos. Applied Environmental Microbiology, 69 (1),241-251. 

“PRODUCTION OF POLYHYDROXYALKANOATES BY MIXED MICROBIAL CULTURES” (2003). M.A.M. Reis, L.S. Serafim, P.C. Lemos, A.M. Ramos, F.R. Aguiar, M.C.M. van Loosdrecht; Bioprocess Biosystem Engineering, 23 (5), 377-385. 

“METHODS FOR DETECTION AND VISUALIZATION OF INTRACELLULAR POLYMERS STORED BY POLYPHOSPHATE-ACCUMULATING MICROORGANISMS” (2002) L.S. Serafim, P.C. Lemos, C. Levantesi, V. Tandoi, H. Santos, M.A.M. Reis; Journal of Microbiological Methods, 51(1), 1-18. 

“CHANGE IN METABOLISM OF PHA ACCUMULATION BY ACTIVATED SLUDGE MODIFYING OPERATING CONDITIONS” (2002) L.S. Serafim, P.C. Lemos, M.A.M. Reis; Water Science and Technology, 46(1-2), 353-356.

“EFFECT OF PH CONTROL ON EBPR STABILITY AND EFFICIENCY” (2002). L.S. Serafim, P.C. Lemos, M.A.M. Reis; Water Science and Technology, 46 (4-5), 179-184. 

“ANALYSIS OF THE MICROBIAL COMMUNITY STRUCTURE AND FUNCTION OF A LABORATORY SCALE ENHANCED BIOLOGICAL PHOSPHATE REMOVAL REACTOR” (2002). C. Levantesi, L.S. Serafim, G.R. Crocetti, P.C. Lemos, S. Rossetti, L.L. Blackall, M.A.M. Reis, V. Tandoi; Environmental Microbiology, 4 (10), 559-569. 

Ongoing Supervisions

André Oliveira

PhD Student

Projects

Biopolymers production as a new concept on wastewater treatment - POLIBIO (PTDC/AAC-AMB/101050/2008)

PartnerFundação para a Ciência e a Tecnologia
Biopolymers Industrial wastewater treatment Anaerobic/aerobic Mixed cultures

ECOBIOTEC - Ecobiotechnology based on the use of mixed microbial consortium producing PHA from waste carbon sources (PTDC/AAC-AMB/111316/2009)

PartnerFundação para a Ciência e a Tecnologia
microbial mixed cultures biopolymers anaerobic/aerobic organic waste valorization

Ecopolyol - Desenvolvimento do processo de produção de polióis a partir de resíduos de biomassa (ECOPOLYOL)

PartnerIndustry National
Construção e desenvolvimento de uma Instalação Piloto para Demonstração Industrial, certificação e validação do processo industrial do ponto de vista de Boas Práticas e Tecnologia Segura, obtenção de amostras industriais e certificação produto. Testar a viabilidade química e física das matérias primas.

Immunosensory integrated system for a fast and efficient detection of the coronavirus SARS-CoV-2 (SENSECOR)

PartnerIndustry National
In view of the worldwide pandemic caused by SARS-CoV-2 coronavirus, it is urgent to create user-friendly and cost-effective tools capable of providing an early, fast and efficient diagnostic of infection by citizens. In this sense, the SENSECOR project aims to develop Proof of Concept of an innovative and unprecedented system that integrates sev...

Innovative multifunctional nanofibrouS MembrAnes for Removal of mycoToxins in liquid foods (i-multiSMART)

PartnerFundação para a Ciência e a Tecnologia

Innovative Products and Technologies from Eucalyptus Project (InPacTus)

PartnerIndustry National
Inpactus, to be developed by the Consortium, aims to develop new solutions, such as cellulosic pulps with innovative features, new paper products with different specificities and functions, tissue paper with innovative properties, new bioproducts, biofuels and other materials obtained from the deconstruction and conversion of forest biomass and ...

MICROBIAL CONTRIBUTION TO THE VALORIZATION OF WASTE/BY-PRODUCTS FROM BIOFUELS PRODUCTION (PTDC/AAC-AMB/100790/2008)

Local CoordinatorFundação para a Ciência e a Tecnologia
Biofuels polyhydroxyalkanoates Glycerol Mixed microbial cultures (MMC)

NANOBINDER – biogenic polymeric NANOparticles functionalized to BIND metals for Eco-friendly applications: bioRemediation and bioSensors (PTDC/AAG-REC/3004/2014)

PartnerFundação para a Ciência e a Tecnologia
The exploration of uranium in Portugal from 1908 to 2001 resulted in huge hotspots of metal exposure. Despite the overall success of conventional remediation works to counteract the associated risks, there are still mine effluents and/or nonpoint discharges (leaching/runoff events) jeopardizing adjacent aquatic systems. Bioremediation has been a...

Publications

Conversion of cheese whey into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Haloferax mediterranei

Pais, J; Serafim, LS; Freitas, F; Reis, MAM
2016, NEW BIOTECHNOLOGY, 33, 1, 224-230.

Long-term operation of a two-stage polyhydroxyalkanoates production process from hardwood sulphite spent liquor

Queiros, D; Fonseca, A; Lemos, PC; Serafim, LS
2016, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 91, 9, 2480-2487.

Unveiling PHA-storing populations using molecular methods

Queiros, D; Lemos, PC; Rossetti, S; Serafim, LS
2015, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 99, 24, 10433-10446.

Adaptation of Scheffersomyces stipitis to hardwood spent sulfite liquor by evolutionary engineering

Pereira, SR; Nogue, VSI; Frazao, CJR; Serafim, LS; Gorwa-Grauslund, MF; Xavier, AMRB
2015, BIOTECHNOLOGY FOR BIOFUELS, 8.

Improvement on the yield of polyhydroxyalkanotes production from cheese whey by a recombinant Escherichia coli strain using the proton suicide methodology

Pais, J; Farinha, I; Freitas, F; Serafim, LS; Martinez, V; Martinez, JC; Arevalo-Rodriguez, M; Prieto, MA; Reis, MAM
2014, ENZYME AND MICROBIAL TECHNOLOGY, 55, 151-158.

PHA production by mixed cultures: A way to valorize wastes from pulp industry

Queiros, D; Rossetti, S; Serafim, LS
2014, BIORESOURCE TECHNOLOGY, 157, 197-205.

Use of hardwood sulphite spent liquor for acclimating a polyhydroxyalkanoate storage capacity of a mixed microbial culture

Queiros, D; Serafim, LS; Rossetti, S
2014, NEW BIOTECHNOLOGY, 31, S100-S101.

Bioethanol Production: Adaptation of Scheffersomyces stipitis to Hardwood Spent Sulfite Liquor

Xavier, AMRB; Frazao, CJR; Pereira, SR; Nogue, VSI; Serafim, LS; Gorwa-Grauslund, MF
2014, NEW BIOTECHNOLOGY, 31, S101-S101.

Production of bacterial cellulose by Gluconacetobacter sacchari using dry olive mill residue

Gomes, FP; Silva, NHCS; Trovatti, E; Serafim, LS; Duarte, MF; Silvestre, AJD; Neto, CP; Freire, CSR
2013, BIOMASS & BIOENERGY, 55, 205-211.

Advances in ethanol production from hardwood spent sulphite liquors

Pereira, SR; Portugal-Nunes, DJ; Evtuguin, DV; Serafim, LS; Xavier, AMRB
2013, PROCESS BIOCHEMISTRY, 48, 2, 272-282.

Biopolymer Production by Mixed Microbial Cultures: Integrating Remediation with Valorization

In Martin Koller (Eds.), Microbial Biopolyester Production, Performance and Processing
Luísa Seuanes Serafim, Diogo Queirós, Simona Rossetti and Paulo Costa Lemos
2016, 226-264, Bentham Science Publishers.
ISBN: 978-1-68108-326-1

Acidogenic Valorisation of High Strength Waste Products from Food Industry

Industrial Waste
Arroja L, Capela I,Nadais H, Serafim LS, Silva S
2011, Rijeka, InTech.
ISBN: 978-953-51-0253-3

Second Generation Bioethanol from Lignocellulosics: Processing of Hardwood Sulphite Spent Liquor

Bioethanol
Fernandes DLA, Pereira SR, Serafim LS, Evtuguin DV, Xavier AMRB
2011, Rijeka, InTech.

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