Ongoing Supervisions
Projects
Aeration of multiphase biological reactors (POCTI/EQU/44427/2002)
PartnerFundação para a Ciência e a Tecnologia
Biological reactors Aeration Multiphase PerfluorocarbonsAnchoring Basic Parameters for fundamental predictive models in Liquid Salt Systems (PTDC/QUI/72903/2006)
PartnerFundação para a Ciência e a Tecnologia
Ionic Liquids Vapor Pressure Enthalpy of vaporization Vapor Liquid EquilibriumAnticorpos de aves com elevada pureza e estabilidade como biofármacos alternativos no combate à resistência antimicrobiana (antYmicrob)
CoordinatorIndustry National
O projeto antYmicrob ambiciona aumentar e validar à escala pré-industrial um processo de purificação desenvolvido para anticorpos imunoglobulina Y, e validar o processo com ovos hiperimunes para bactéria Staphylococcus aureus resistente à meticilina (MRSA), assegurando a atividade, estabilidade e não toxicidade dos anticorpos obtidos por ensaios...Aplicação de SAB constituídos por líquidos iónicos no desenvolvimento de diagnósticos de câncer do sistema adrenalina (MCT/CNPq 14/2010 Universal)
Local CoordinatorOther International
DeepBiorefinery - Natural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefinerie (DeepBiorefinery )
PartnerFundação para a Ciência e a Tecnologia
natural deep eutetic solvents, biorefinery, green separation processesDesenvolvimento de nanomateriais sustentáveis para a purificação de fármacos anti-leucémicos (NanoPurAsp)
PartnerFundação para a Ciência e a Tecnologia
Development of a sustainable technology for the extraction and purification of chlorophylls from biomass (EXPL/QEQ-PRS/0224/2013 )
PartnerFundação para a Ciência e a Tecnologia
chlorophyll extraction bioresources ionic liquidsDevelopment of Ionic-Liquid-based Devices for the Removal of Cytostatic Drugs From Urine Excreted by Cancer Patients (IonCytDevice)
CoordinatorFundação para a Ciência e a Tecnologia
Development of New Oxygen Therapeutics using Fluorinated Ionic Liquids (PTDC/EQU-FTT/118800/2010)
Local CoordinatorFundação para a Ciência e a Tecnologia
Fluorinated Ionic Liquids Perfluoroalkanes Phase Equilibria Oxygen SolubilityEquilibrium and Interfacial Properties of Water + Oil Systems (POCI/EQU/58239/2004)
PartnerFundação para a Ciência e a Tecnologia
Phase Equilibria Interfacial Tension Aqueous Systems ModelingEXIL - Exchange on Ionic Liquids (EXIL)
PartnerEuropean Comission
The objective of this Action is to coordinate European research activities and knowledge exchange on ionic liquids (ILs, low melting salts, many of them liquid at room temperature and below) and to explore their full potential in the context of fundamental and applied chemistry, materials science and engineering. The COST Action will provide a c...Extraction and Purification of Biomolecules (FAPITEC/FUNTEC/CNPq n. 10/2011)
Local CoordinatorOther International
Igy Technology: A Purication Platform using Ionic-Liquid-Based Aqueous Biphasic Systems (IGYPURTECH)
CoordinatorEuropean Comission
With the emergence of antibiotic-resistant pathogens the development of antigen-specific antibodies for use in passive immunotherapy is, nowadays, a major concern in human society. Despite the most focused mammal antibodies, antibodies obtained from egg yolk of immunized hens, immunoglobulin Y (IgY), are an alternative option that can be obtaine...Integration of human fluids pretreatment and detection of cancer biomarkers using ionic-liquid-based aqueous biphasic systems in microfluidic devices (ILSurvive)
PartnerFundação para a Ciência e a Tecnologia
Cancer biomarkers Detection Ionic liquids Microfluidic devicesIonic liquid-based supports for pre-miRNAs purification targeting Alzheimer's disease (PUREmiRSILs)
Local CoordinatorFundação para a Ciência e a Tecnologia
Ionic Liquids as Promoters of Aqueous Biphasic Systems: The Role of van der Waals and Coulomb Interactions (PTDC/QUI-QUI/121520/2010)
PartnerFundação para a Ciência e a Tecnologia
Aqueous Biphasic System Ionic Liquid Inorganic Salt PolymerMultiBiorefinery - Multi-purpose strategies for broadband agro-forest and fisheries by-products valorization: a step forward for a truly integrated biorefinery (SAICTPAC/0040/2015)
PartnerFundação para a Ciência e a Tecnologia
Biorrefinaria; Subprodutos e resíduos; Novos processos de extração e conversão; BioprodutosNanostructured ZnO and ZnO/nanocarbon composites for biosensing applications (NANOBIOSENSE)
PartnerFundação para a Ciência e a Tecnologia
The expanding interest regarding biosensing and early diseases’ diagnosis has led to an exponential growth of R&D efforts in order to find the most suitable materials and sensing mechanisms to achieve high sensitivity and selectivity at low production cost. In this framework, the present project envisages the development of ZnO-based nanostructu...Nova abordagem terapêutica para desacelerar a progressão da doença de Parkinson; (PDSolve)
Local CoordinatorIndustry National
A doença de Parkinson (DP) é a segunda doença neurodegenerativa mais prevalente no mundo, com profundos impactos económicos e sociais. O objetivo deste projeto é provar a eficácia farmacológica e aplicação terapêutica à DP do i...Optimization and Scale-up of Novel Ionic-Liquid- based Purification Processes for Recombinant Green Fluorescent Protein produced by Escherichia coli (FAPESP/19793/2014)
PartnerFundação para a Ciência e a Tecnologia
biopharmaceuticals, fluorescent proteins, purification, aqueous biphasic systemsThe best of two worlds: Ionic liquids as Active Pharmaceutical Ingredients (PTDC/EQU-EPR/104554/2008)
Local CoordinatorFundação para a Ciência e a Tecnologia
Ionic Liquids Fluoroquinolones Bioavailability Solubility related propertiesVapour Liquid Equilibrium of Pure Ionic Liquids and their Mixtures with Organic Solvents (PTDC/EQU-FTT/65252/2006)
PartnerFundação para a Ciência e a Tecnologia
Ionic Liquids Vapour pressure Molar enthalpies and entropies of vaporization Vapour Liquid equilibriumPublications
Characterization of aqueous biphasic systems composed of ionic liquids and a citrate-based biodegradable salt
Passos, H; Ferreira, AR; Claudio, AFM; Coutinho, JAP; Freire, MG
2012, BIOCHEMICAL ENGINEERING JOURNAL, 67, 68-76.
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Density and Viscosity Data for Binary Mixtures of 1-Alkyl-3-methylimidazolium Alkylsulfates plus Water
Bhattacharjee, A; Varanda, C; Freire, MG; Matted, S; Santos, LMNBF; Marrucho, IM; Coutinho, JAP
2012, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 57, 12, 3473-3482.
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Increased significance of food wastes: Selective recovery of added-value compounds
Reis, IAO; Santos, SB; Santos, LA; Oliveira, N; Freire, MG; Pereira, JFB; Ventura, SPM; Coutinho, JAP; Soares, CMF; Lima, AS
2012, FOOD CHEMISTRY, 135, 4, 2453-2461.
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Influence of the anion on the surface tension of 1-ethyl-3-methylimidazolium-based ionic liquids
Almeida, HFD; Teles, ARR; Lopes-da-Silva, JA; Freire, MG; Coutinho, JAP
2012, JOURNAL OF CHEMICAL THERMODYNAMICS, 54, 49-54.
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Evaluation of the impact of phosphate salts on the formation of ionic-liquid-based aqueous biphasic systems
Mourao, T; Claudio, AFM; Boal-Palheiros, I; Freire, MG; Coutinho, JAP
2012, JOURNAL OF CHEMICAL THERMODYNAMICS, 54, 398-405.
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Optimization of the gallic acid extraction using ionic-liquid-based aqueous two-phase systems
Claudio, AFM; Ferreira, AM; Freire, CSR; Silvestre, AJD; Freire, MG; Coutinho, JAP
2012, SEPARATION AND PURIFICATION TECHNOLOGY, 97, 142-149.
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Overview of the Liquid-Liquid Equilibria of Ternary Systems Composed of Ionic Liquid and Aromatic and Aliphatic Hydrocarbons, and Their Modeling by COSMO-RS
Ferreira, AR; Freire, MG; Ribeiro, JC; Lopes, FM; Crespo, JG; Coutinho, JAP
2012, INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 51, 8, 3483-3507.
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Ionic-Liquid-Based Aqueous Biphasic Systems with Controlled pH: The Ionic Liquid Anion Effect
Ventura, SPM; Sousa, SG; Serafim, LS; Lima, AS; Freire, MG; Coutinho, JAP
2012, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 57, 2, 507-512.
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Thermophysical Properties of Five Acetate-Based Ionic Liquids
Almeida, HFD; Passos, H; Lopes-da-Silva, JA; Fernandes, AM; Freire, MG; Coutinho, JAP
2012, JOURNAL OF CHEMICAL AND ENGINEERING DATA, 57, 11, 3005-3013.
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Impact of Self-Aggregation on the Formation of Ionic-Liquid-Based Aqueous Biphasic Systems
Freire, MG; Neves, CMSS; Lopes, JNC; Marrucho, IM; Coutinho, JAP; Rebelo, LPN
2012, JOURNAL OF PHYSICAL CHEMISTRY B, 116, 26, 7660-7668.
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Waste Valorisation Using Ionic Liquids
Francisca e Silva; Ana Sousa; Mara Freire; João Coutinho
2022, Royal Society of Chemistry.
ISBN:
978-1-83916-468-2
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Ionic-Liquid-Based Aqueous Biphasic Systems: Fundamentals and Applications
Mara G. Freire
2016, 315, Berlin , Springer Berlin Heidelberg.
ISBN:
978-3-662-52875-4
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Nucleic Acids Stabilization with Ionic Liquids and Deep Eutectic Solvents
In Noureddine Abidi and Julia Shamshina (Eds.), Properties and Applications of Ionic Liquids
Almeida J.S.; Capela E.V.; Tavares A.P.M.; Freire M.G.
2023, Properties and Applications of Ionic Liquids, 181-218, Nova Science Publisher Inc..
ISBN:
979-888697873-5; 979-888697635-9
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Microbial Enzymes in the Bioremediation of Pollutants
In Inamuddin, M.Phil (Eds.), Bioremediation for Environmental Pollutants
Flávia F. Magalhães, Maria I. Bonifácio, Ana M. Ferreira, Mara G. Freire and Ana P. M. Tavares
2023, 1-37, Benthan Science.
ISBN:
978-981-5123-53-1
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Relevance on the Recovery of High Economic Value Elements and Potential of Ionic Liquids
Handbook of Solid Waste Management: Sustainability through Circular Economy
Almeida, J. C.; Cardoso, C. E. D.; Trindade, T.; Freire, M. G.; Pereira, E.
2022.
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Anti-Cancer Biosurfactants
In Springer (Eds.), Microbial Biosurfactants
Flávia F. Magalhães, João C. F. Nunes, Marília T. Araújo, Ana M. Ferreira, Mafalda R. Almeida, Mara G. Freire, Ana P. M. Tavares
2021, 159-196.
ISBN:
10.1007/978-981-15-6607-3_8
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Recovery and Purification of (Bio)Pharmaceuticals Using (Nano)Materials
In Bentham Science (Eds.), Recent Advances in Analytical Techniques Volume: 4
Ana P. M. Tavares, Márcia C. Neves, Tito Trindade and Mara G. Freire
2020, 58-93.
ISBN:
978-981-14-0510-5
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Aqueous biphasic systems formed by cholinium-based ionic liquids and mixtures of polymers
In Rasmus Fehrmann, Catherine Santini (Eds.), Ionic Liquids: Synthesis, Properties, Technologies and Applications
Teresa B.V Dinis, Catarina M.S.S. Neves, Luís Barbosa, João A.P. Coutinho, Mara G. Freire
2019, 29-54, Berlin, Walter de Gruyter GmbH.
ISBN:
978-3-11-058201-7
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Application of Ionic Liquids in Separation and Fractionation Processes
In Buxing Han and Tianbin Wu (Eds.), Green Chemistry and Chemical Engineering
Capela, EV; Coutinho, JAP; Freire, MG
2019, 637-665, New York, NY, Springer.
ISBN:
978-1-4939-9059-7
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Immobilization of Ionic Liquids, Types of Materials, and Applications
In Zhang S. (Eds.), Encyclopedia of Ionic Liquids
Augusto Q. Pedro, João A. P. Coutinho, Mara G. Freire
2019, Springer.
ISBN:
978-981-10-6739-6
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Ionic Liquids and Deep Eutectic Solvents in the Field of Environmental Monitoring
In Płotka-Wasylka, Justyna, Namieśnik, Jacek (Eds.), Green Analytical Chemistry: Past, Present and Perspectives
Cardoso I.S., Pedro A.Q., Silvestre A.J.D., Freire M.G.
2019, 203-240, Singapore, Springer.
ISBN:
978-981-13-9104-0
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Use of Nanomaterials in the Pretreatment of Water Samples for Environmental Analysis
In Bhat AH, Jawaid M, O Sulliman FE, Al-Kindy SM (Eds.), Nanomaterials for Healthcare, Energy and Environment
Bernardo S, Sousa ACA, Neves MC, Freire MG
2019, 103-142, Aveiro, Springer Nature.
ISBN:
978-981-13-9832-2
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Application of Ionic Liquids in Separation and Fractionation Processes
In Robert A. Meyers (Eds.), Encyclopedia of Sustainability Science and Technology
Capela, EV; Coutinho, JAP; Freire, MG
2018, 1-29, New York, USA, Springer.
ISBN:
978-1-4939-2493-6
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Ionic Liquids in Bioseparation Processes
In Toshiyuki ItohYoon-Mo Koo (Eds.), Advances in biochemical engineering/biotechnology
Belchior D.C.V., Duarte I.F., Freire M.G.
2018, 1-29, Springer, Berlin.
ISBN:
978-3-030-23080-7
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Monoclonal Antibodies – Addressing the Challenges on the Manufacturing Processing of an Advanced Class of Therapeutic Agents
In Atta-ur-Rahman (Eds.), Frontiers in Clinical Drug Research-Anti Infectives
Capela, EV; Aires-Barros, MR; Freire, MG; Azevedo, AM
2017, 142-203, Sharjah, UAE, Bentham Science.
ISBN:
978-1-68108-488-6
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Imunoglobulina Y (IgY): uma Alternativa Promissora aos Anticorpos de Mamíferos
In Manuel A. Coimbra (Eds.), Bioquímica e Bem-Estar
M. V. Quental, M. R. Almeida, J. Gomes, J. Resende,P. Domingues, M. G. Freire
2017, Lisboa, Edições Afrontamento.
ISBN:
978-972-36-1560-9
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Aplicação de Sistemas Aquosos Bifásicos na Purificação de Biomoléculas
In Á. S. Lima and C. C. Santana (Eds.), Processos de Extração e Purificação de Biomoléculas
Á. S. Lima, N. S. O. Placido, R. L. S. França, I. O. A. Reis, M. M. Pereira, M. G. Freire
2017, Brazil, EDUNIT - Editora Universitária Tiradentes.
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CHAPTER 8:Ionic Liquids as Efficient Tools for the Purification of Biomolecules and Bioproducts from Natural Sources
In Rafal Bogel-Lukasik (Eds.), Ionic Liquids in the Biorefinery Concept : Challenges and Perspectives
Matheus M. Pereira, João A. P. Coutinho and Mara G. Freire
2016, 227-257, Royal Society of Chemistry.
ISBN:
978-1-84973-976-4
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Introduction to Ionic-Liquid-Based Aqueous Biphasic Systems (ABS)
In Mara G. Freire (Eds.), Ionic-Liquid-Based Aqueous Biphasic Systems: Fundamentals and Applications
Mara G. Freire
2016, 1-25, Springer Berlin Heidelberg.
ISBN:
978-3-662-52875-4
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Predicting the Thermodynamic Behavior of Water & Ionic Liquids Systems Using COSMO-RS
In Gaune-Escard M, Seddon K R (Eds.), Molten Salts and Ionic Liquids: Never the Twain?
Freire MG, Santos LMNBF, Marrucho IM, Coutinho JAP
2010, John Wiley & Sons, Inc..
ISBN:
978-0471773924
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Waste Valorisation Using Ionic Liquids
Francisca e Silva; Ana Sousa; Mara Freire; João Coutinho
2022, Royal Society of Chemistry.
ISBN:
978-1-83916-468-2
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Ionic-Liquid-Based Aqueous Biphasic Systems: Fundamentals and Applications
Mara G. Freire
2016, 315, Berlin , Springer Berlin Heidelberg.
ISBN:
978-3-662-52875-4
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Separation of dyes with reversible aqueous biphasic systems
Ana Maria da Conceição Ferreira
2013, supervised by Ana M. Fernandes and Mara G. Freire.
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Aeration and Extraction in Multiphase Biological Reactors
Mara Guadalupe Freire Martins Martins
2007, supervised by João Manuel da Costa Araújo Pereira Coutinho; Isabel Marrucho.
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