Carmen Sofia da Rocha Freire Barros

Coordinating Researcher

Short CV

 

Researcher ID :  http://www.researcherid.com/rid/E-4549-2013

 

Carmen Freire was born in 1976 in Venezuela. In 1994 she concluded high school at Escola Secundária José Estevão (Aveiro), and, motivated by an enormous interest in Chemistry, started her graduation in Industrial Chemistry at the University of Aveiro (UA).

 

After concluding her graduation in 1998, she started her PhD work, “Eucalyptus globulus Low Molecular Weight Organic Compounds: Behavior During Wood Kraft Pulping and Pulp Bleaching”, at the Chemistry Department of the University of Aveiro. In early 2003, she embraced a post-doctoral project on “Surface Chemical Modification of Cellulose Fibers for Novel Paper and Composite Materials”, developed jointly between the Department of Chemistry of UA and the EFPG (presently Pagora), Institut Polytechnique de Grenoble a forefront research group in the domain of Macromolecular Materials from Renewable Resources. During this period, she got a solid background and knowledge on the development and characterization of natural polymers-based materials.

 

Since 2006, as a Auxiliary Reseracher (from January 2006 to June 2011) and now as a Principal Researcher (FCT Researcher), she has leaded the research on materials and composites from cellulose and other polysaccharides within BioPol4Fun group at CICECO/UA .

 

Main achievements:

 

  • 164 articles in SCI journals (December 2018).
  • 3 National patents and 2 European patent.
  • More than 170 communications in International Conferences
  • Referee for several high impact factor international journals in the areas of biomacromolecules, polysaccharides, green and sustainable chemistry and materials in general
  • Concluded the supervision of 3 PhD, 3 Post-Docs, 31 Master theses,

Scientific Interests

Her research interests are centred on the Chemistry of polymers from renewable resources (caracterization and application) and development of new sustainable composite materials and  nanostructured materails  for disntinct appications

 

Present Research Group

BioPol4Fun- Innovation in biopolymeric functional materials and bioactive compounds

Supervisor or co-supervisor of 5 Pos-doctorate students, 10 PhD student and 4 Master students.

Main present collaborators

 

Armando Silvestre, Ana Barros-Timmons, Mara Freire, João Coutinho,Graça Neves, Paulo Claro, Iola Duarte  e Filipe Figueiredo (Department of Chemistry, University of Aveiro),

Adelaide Almeida, Helena Oliveira (Department of Biology, University of Aveiro)

Paula Alexandrina Marques (TEMA, University of Aveiro)

Isabel Marrucho (IST)

Fátima Duarte (CEBAL, Beja)

Catarina Rosado (Universidade Lusófona, Lisboa)

Isabel Almeida e Paulo Costa (Faculty of Pharmacy, University of Porto)

Fernando Dourado e Miguel Gama (University of Minho)

 

Stefan Spirk (TU Graz,  Austria)

Hélder Santos (University of Helsinki, Finland)

Pedro Fardim  (Abo Akademi, Finland and University of Leuven, Belgium)

Ana Alonsa Varona (UPV, San Sebastian)

Patrizia Sadocco (SSCCP, Stazione Sperimentale Carta, Cartoni e Paste per Carta, Italy)

 

 

Selected Publications

 

Nuno H.C.S. Silva, Carla Vilela, Adelaide Almeida, Isabel M. Marrucho, Carmen S.R.Freire, Pullulan-based nanocomposite films for functional food packaging: Exploiting lysozyme nanofibers as antibacterial and antioxidant reinforcing additives, Food Hydrocolloids, 2018, 77, 921-930.

Louise Saidi, Carla Vilela, Helena Oliveira, Armando J.D. Silvestre, Carmen S.R. Freire, “Poly(N-methacryloyl glycine)/nanocellulose composites: pH-sensitive systems for controlled release of diclofenac”, Carbohydr. Polym., 2017, 169, 357-365.

Carla Vilela, Ricardo J. B. Pinto, Joel Coelho, M. R. M. Domingues, Sara Daina, Patrizia Sadocco, Sónia A. O. Santos, Carmen S. R. Freire, Bioactive chitosan/ellagic acid films with UV-light protection for active food packaging, Food Hydrocolloids, 2017, 73, 120-128.        

Joana F.B. Barata, Ricardo J.B. Pinto, Vanda I.R.C. Vaz Serra, Armando J.D. Silvestre, Tito Trindade, Maria Graça P.M.S. Neves, José A.S. Cavaleiro, Sara Daina, Patrizia Sadocco, Carmen S.R. Freire, “Fluorescent bioactive corrole grafted-chitosan films”, Biomacromolecules, 2016, 17, 1395-1403.                                                                                                                      

Liliana C. Tomé, Ricardo J. B. Pinto, Eliane Trovatti, Carmen S. R. Freire, Armando J. D. Silvestre, Carlos Pascoal Neto, Alessandro Gandini, Transparent bionanocomposites with improved properties prepared from acetylated bacterial cellulose and poly(lactic acid) through a simple approach, Green Chem., 2011, 13, 419-427

Present projects

NanoBioinks- Engineering bio-based nanofibers for the development of high performance bioinks for 3D bioprinting”, CENTRO-01-0145-FEDER-031289, FCT/MCTES, (PI), 2018-                                                                                                                 
CORLUTNA- Systems based on corrolic macrocycles for luminescent thermometry  at nanoscale”, Projeto nº 031523 com o apoio financeiro da Fundação para a Ciência e Tecnologia/MCTES,  (co-PI) 2018-                                                                                             
“InPaCTus-  Products and Technologies from eucalipt”, RCI, I&DANI/AICEP, coordinated by Navigator Company, (PI of 3 sub-projects)

                                          
MultiBiorefinery – Estratégias multiuso para a valorização de uma gama alargada de subprodutos agroflorestais e das pescas: Um passo em frente na criação de uma biorrefinaria integrada” (POCI-01-0145-FEDER-016403), (team member)                                       
“AgroForWealth – Biorefinery of agro-forest residues: a strategy for the valorization of resources for wealth and sustainability“; CCDRC (team member) 

                            
INNOVATE- Implantable organic Devices for advanced therapies”, University of Algarve, University of Aveiro, PTDC/EEI-AUT/5442/2014, (PI at UA)


DeepBiorefinery: "Natural Deep eutectic solvents: a platform to boost Eucalyptus globulus and Quercus suber cork integrated biorrefinery”, Universidade de Aveiro e ITQB. PTDC/AGR-TEC/1191/2014 (team member)

Ongoing Supervisions

Projects

Bioeconomia para Têxtil e Vestuário (BE@T)

Local CoordinatorIndustry National
Apoiada pelo Plano de Recuperação e Resiliência (PRR), a indústria têxtil nacional vai investir 138 milhões de euros na bioeconomia sustentável, procurando a mudança de paradigma para o setor e a criação de produtos de alto valor ...

Engineering self-propelled cellulose-based Janus microrobots (Cell4Janus)

PartnerFundação para a Ciência e a Tecnologia

From Fossil To Forest (FF2F (Biocomposites))

Local CoordinatorIndustry National
This Innovation Pact is aimed at developing cellulose-based packaging and products to replace fossil-based plastics. In this context, it comprises the following six work packages: (1) high yield pulp and brown paper; (2) paper with increased mechanical strength; (3) paper with barrier properties; (4) biocomposites; (5) paper sensors for...

Inovação na Fileira da Resina Natural para Reforço da Bioeconomia Nacional (RN21)

PartnerIndustry National
A transição para uma economia mais sustentável, oferece inúmeras oportunidades para revitalizar os setores mais tradicionais da economia portuguesa, onde destacamos a produção e transformação da resina natural.O Projeto Integrado RN21 – Ino...

Pacto da Bioeconomia azul (BIOECOAZUL (Termoendurecíveis))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Pacto da Bioeconomia azul (BIOECOAZUL (Termoplásticos a desenvolver))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Pacto da Bioeconomia azul (BIOECOAZUL (Plásticos já existentes))

Local CoordinatorIndustry National
The world needs a new business model capable of economic growth decoupling raw materials from natural resources. Thus the Blue Bioeconomy Pact has embraced the challenge of reindustrialising Portuguese industries with the integration of blue biotechnology solutions in the value chains, enhancing the sustainable use of marine bio-resourc...

Bacterial Cellulose Membranes for Proton Exchange Fuel Cells (EXPL/CTM-ENE/0548/2012)

PartnerFundação para a Ciência e a Tecnologia
Bacterial cellulose fuell cells proton exchange membranes in situ polymerization/grafting

BIOBLOCKS - Concepção de produtos de base biológica como percursores para a bioindústria de síntese química e de biomateriais a pertir de fontes renováveis lenhocelulósicas (BioBlocks)

Local CoordinatorIndustry National
O aumento dos preços de petróleo e uma maior apetência dos consumidores por produtos ecológicos e sustentáveis, têm vindo a viabilizar progressivamente o processo de produção e comercialização de biocombustíveis, bioquímicos e biopolímeros com base em materiais de fontes renováveis alternativos aos de origem petroquímica, permitindo a emergência...

Bioinspired nanostructured biocomposites based on proteins and polysaccharides nanofibrils (EXPL/CTM-POL/1802/2013)

CoordinatorFundação para a Ciência e a Tecnologia
Proteins and polysaccharides nanofibrils Nanostructured materials Self-assembly Biomedical applications

Controlled chemical modification of polysaccharides for the development of novel materials (PTDC/QUI/68472/2006 )

CoordinatorFundação para a Ciência e a Tecnologia
Polysaccharides Chemical modification Composites Functional materials

Corrole based systems for luminescent thermometry at nanoscale (CORLUTNA)

PartnerFundação para a Ciência e a Tecnologia
Temperature (T) is a fundamental parameter that affects the behavior of physical, chemical and biological systems in a wide variety of ways. Measuring T is important in many fields: photonic devices, nano/microelectronics, medical diagnostics, nanomedicine. Regarding the several classes of thermometers, one possible approach is to use dye lumine...

DeepBiorefinery - Natural Deep Eutectic Solvents: A platform to Boost Eucalyptus globulus and Quercus suber cork integrated Biorefinerie (DeepBiorefinery )

PartnerFundação para a Ciência e a Tecnologia
natural deep eutetic solvents, biorefinery, green separation processes

Desenvolvimento de rolhas de cortiça produzidas por processos mais verdes e sustentáveis (GCORK)

PartnerIndustry National
"O Projeto GCORK tem por objetivo capacitar a Amorim Cork a ser a primeira empresa a lançar no mercado uma gama de rolhas de cortiça aglomerada com colas e tratamentos de superfície Bio, produzidas por processos mais verdes e mais sustentáveis. Este produto será extremamente inovador po...

Development of new polyesters derived from 2,5-furandicarboxylic acid (PTDC/QUI-QUI/101058/2008)

PartnerFundação para a Ciência e a Tecnologia
2,5-furandicarboxylic acid Polyesters synthesis Materials from renewable sources Biorefinery

Engenharia de nanofibras de origem biológica para o desenvolvimento de biotintas nanoestruturadas de elevada performance para bio-impressão 3-D (NANOBIOINKS)

PartnerFundação para a Ciência e a Tecnologia

Eucalyptus triterpenic biological activity (PTDC/AGR-FOR/3187/2012)

Local CoordinatorFundação para a Ciência e a Tecnologia
Eucalyptus spp Ionic Liquids Antitumoral Activity Metabolomics

FLUI - Sistemas de extrusão duplo paralelo de ácido polilático com injeção modular de compostos bioativos para a produção de filmes flexíveis mono e multi-camada biofuncionais para embalagens de produtos alimentares a partir de resíduos lenho-celulós (FLUI)

PartnerIndustry National
A solução apresentada pelo projeto FLUI visa o sucesso da obtenção de equipamentos inovadores e disruptivos com as soluções presentes no mercado (TRL6) para a produção de filmes flexíveis biofuncionais com flexibilidade, mono e multicamada...

Green chemicals and technologies for the wood-to-textile value chain. (GRETE)

PartnerEuropean Comission
The GRETE project will tackle the challenges caused by increased global demand for sustainable textile fibres by offering new breakthroughs in the wood-to-textile value chain. The substitution of cotton by man-made cellulose fibres is also necessary because of sustainability issues. Currently the raw material base for the production of man-made ...

GREENPEC - Desenvolvimento de um plastificante primário para PVC, de origem animal e livre de ftalatos (GREENPEC )

PartnerIndustry National
O objetivo principal deste projeto, levado a cabo pelo consórcio entre a Sapec Química e a Universidade de Aveiro, consiste no desenvolvimento de um plastificante primário para PVC originado a partir de óleos vegetais, os quais são considerados recursos renováveis e agentes de crescimento sustentável. Com o cumprimento destes objetivos, prevê-se...

INNOVATE-Implantable Organic Devices for Advanced Therapies (INNOVATE)

Local CoordinatorFundação para a Ciência e a Tecnologia
Bioelectronica; Transdutores electrónicos implantáveis; Medicina regenerativa; Sinais bioelectrónicos

Innovative Products and Technologies from Eucalyptus Project (InPacTus)

PartnerIndustry National
Inpactus, to be developed by the Consortium, aims to develop new solutions, such as cellulosic pulps with innovative features, new paper products with different specificities and functions, tissue paper with innovative properties, new bioproducts, biofuels and other materials obtained from the deconstruction and conversion of forest biomass and ...

Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials (PTDC/SAU-TOX/120953/2010)

PartnerFundação para a Ciência e a Tecnologia
metabolic profiling and metabonomics silver nanoparticles toxicological and biological effects nanotoxicology

Publications

API-DES: improving drug solubility with deep eutectic solvents

Ribeiro-Claro, P; Rudic, S; Nolasco, M; Araujo, C; Freire, C; Pedro, S; Vaz, PD; Vilela, C
2019, STFC ISIS Neutron and Muon Source.

Extraction and recovery processes for cynaropicrin from Cynara cardunculus L. using aqueous solutions of surface-active ionic liquids

de, Faria, ELP; Gomes, MV; Cláudio, AFM; Freire, CSR; Silvestre, AJD; Freire, MG
2018, BIOPHYSICAL REVIEWS, 10, 3, 915-925.

Effect of unrefined crude glycerol composition on the properties of polyurethane foams

Gama, NV; Soares, B; Freire, CSR; Silva, R; Ferreira, A; Barros-Timmons, A
2018, JOURNAL OF CELLULAR PLASTICS, 54, 3, 633-649.

Pullulan-based nanocomposite films for functional food packaging: Exploiting lysozyme nanofibers as antibacterial and antioxidant reinforcing additives

Silva, NHCS; Vilela, C; Almeida, A; Marrucho, IM; Freire, CSR
2018, FOOD HYDROCOLLOIDS, 77, 921-930.

Hydrogen Bond Dynamics of Cellulose through Inelastic Neutron Scattering Spectroscopy

Araujo, C; Freire, CSR; Nolasco, MM; Ribeiro-Claro, PJA; Rudic, S; Silvestre, AJD; Vaz, PD
2018, BIOMACROMOLECULES, 19, 4, 1305-1313.

NMR Metabolomics Reveals Metabolism-Mediated Protective Effects in Liver (HepG2) Cells Exposed to Subtoxic Levels of Silver Nanoparticles

Carrola, J; Pinto, RJB; Nasirpour, M; Freire, CSR; Gil, AM; Santos, C; Oliveira, H; Duarte, IF
2018, JOURNAL OF PROTEOME RESEARCH, 17, 4, 1636-1646.

Deep Eutectic Solvent Aqueous Solutions as Efficient Media for the Solubilization of Hardwood Xylans

Morais, ES; Mendonca, PV; Coelho, JFJ; Freire, MG; Freire, CSR; Coutinho, JP; Silvestre, AJD
2018, CHEMSUSCHEM, 11, 4, 753-762.

Tuning lysozyme nanofibers dimensions using deep eutectic solvents for improved reinforcement ability

Silva, NHCS; Vilela, C; Pinto, RJB; Martins, MA; Marrucho, IM; Freire, CSR
2018, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 115, 518-527.

Poly(bis[2-(methacryloyloxy)ethyl]phosphate)/Bacterial Cellulose Nanocomposites: Preparation, Characterization and Application as Polymer Electrolyte Membranes

Vilela, C; Martins, APC; Sousa, N; Silvestre, AJD; Figueiredo, FML; Freire, CSR
2018, APPLIED SCIENCES-BASEL, 8, 7.

A concise guide to active agents for active food packaging

Vilela, C; Kurek, M; Hayouka, Z; Rocker, B; Yildirim, S; Antunes, MDC; Nilsen-Nygaard, J; Pettersen, MK; Freire, CSR
2018, TRENDS IN FOOD SCIENCE & TECHNOLOGY, 80, 212-222.

Active packaging

In Galanakis, Charis (Eds.), Sustainable Food Processing and Engineering Challenges
Carvalho, João P.F.; Freire, Carmen S.R.; Vilela, Carla
2021, Academic Press.
ISBN: 9780128227145

Modification of textiles for functional applications

In Md. Ibrahim H. Mondal (Eds.), Fundamentals of Natural Fibres and Textiles
Ana C. Q. Silva, Armando J. D. Silvestre, Carmen S. R. Freire, Carla Vilela
2021, 303-365, Elsevier.
ISBN: 9780128214831

Furanoate-Based Nanocomposites: A Case Study Using Poly(Butylene 2,5-Furanoate) and Poly(Butylene 2,5-Furanoate)-co-(Butylene Diglycolate) and Bacterial Cellulose

In George Z. Papageorgiou (Eds.), Polymers from Renewable Resources
Marina Matos, Andreia Sousa, Nuno H.C.S. silva, Carmen S.R. Freire, Márcia Andrade, Adélio Mnedes, Armando J.D. Silvestre
2018, MDPI.
ISBN: 978-3-03897-451-2

Development and applications of cellulose nanofibres based polymer nanocomposites

In Ehsan Bafekrpour (Eds.), Advanced Composite Materials: Properties and Applications
Carla Vilela, Ricardo J. B. Pinto, Ana R. P. Figueiredo, Carlos Pascoal Neto, Armando J. D. Silvestre, Carmen S. R. Freire
2017, 1-65, Warsaw/Berlin, De Gruyter Open.
ISBN: 9783110574432

Antimicrobial Properties and Therapeutic Applications of Silver Nanoparticles and Nanocomposites

In Alexandru Mihai Grumezesc (Eds.), Antimicrobial Nanoarchitectonics - From Synthesis to Applications
R.J.B. Pinto, M. Nasirpour, J. Carrola, H. Oliveira, C.S.R. Freire, I.F. Duarte
2017, 223-259, Elsevier.
ISBN: 978-0-323-52733-0

Polyethylene Terephthalate: Copolyesters, Composites, and Renewable Alternatives

In P. M. Visakh Mong Liang (Eds.), Poly(ethylene Terephthalate) Based Blends, Composites and Nanocomposites.
Andreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho
2015, 111-139, Elsevier Science Ltd.
ISBN: 9780323313063

Recent advances on the development of antibacterial polysaccharide-based materials, Chitosan, cellulose and starch

In Ramawat, Kishan Gopal, Mérillon, Jean-Michel (Eds.), Polysaccharides: Bioactivity and Biotechnology
V. Coma, C.S.R. Freire and A.J.D. Silvestre
2015, 1751-1803, New York, Springer International Publishing.
ISBN: 978-3-319-16297-3

Polyethylene Terephthalate: Copolyesters, Composites, and Renewable Alternatives

In Visakh P.M., Mong Liang (Eds.), POLY(ETHYLENE TEREPHTHALATE) BASED BLENDS, COMPOSITES AND NANOCOMPOSITES
Andreia F. Sousa, Carla Vilela, Marina Matos, Carmen S.R. Freire, Armando J.D. Silvestre, Jorge F.J. Coelho
2015, Elsevier Inc..
ISBN: 978-0-323-31306-3

2 Bacterial  Cellulose-Based  Nanocomposites: Roadmap for Innovative Materials

Nanocellulose Polymer Nanocomposites: Fundamentals and Applications
A. R. P. Figueiredo, C. Vilela, C. Pascoal Neto, A.J.D. Silvestre and C.S.R. Freire
2014, Scrivener, Willey.
ISBN: 978-1-118-87190-4

The bulk oxypropylation of chitin and chitosan and the characterization of the ensuing polyols

In Senel S, Vårum KM Sumnu MM Hincal AA (Eds.), Advances In Chitin Science
Fernandes S, Freire CSR, Pascoal Neto C, Gandini A
2007, 10, 530-535, Antalya.
ISBN: 978-975-491-250-0

Biofuncionalização de nanocristais de celulose para o desenvolvimento de novos sistemas para tratamento e diagnóstico do cancro

Diogo Pinheiro
2018, supervised by Carmen Freire and Ricardo Pinto.

Biofuncionalização de nanocristais de celulose com ácido fólico para o desenvolvimento de novos sistemas para o diagnóstico e tratamento do cancro

Nicole Silva Lameirinhas
2017, supervised by Ricardo Pinto and Carmen Freire.

Biofuncionalização de nanocristais de celulose com ácido fólico para o desenvolvimento de novos sistemas para o diagnóstico e tratamento do cancro

Fátima Gabriela Guedes Faria
2017, supervised by Carmen Freire and Ricardo Pinto.

Biosynthesis of metallic nanostructures using natural extracts: study of structural and morphological features and evaluation of its therapeutic potential

Madalena Pinheiro Morais
2016, supervised by Ricardo Pinto and Carmen Freire .

Biosynthesis of metallic nanostructures using natural extracts: study of structural and morphological features and evaluation of its therapeutic potential

Catarina dos Reis Viegas
2015, supervised by Carmen Freire and Ricardo Pinto.

Green reduction of graphene oxide with Eucalyptus globulus bark extract

Mariana Rodrigues Ferreira da Silva
2015, supervised by Carmen Freire and Ricardo Pinto.

Characterization of new nanocomposites based on natural matrices (cellulose) and metallic nanostructures of copper

Kornelia Pielak
2014, supervised by Carmen Freire and Ricardo Pinto.

Desenvolvimento de novos nanomateriais híbridos a partir de biopolímeros e nanopartículas metálicas para aplicação em biosensores e catálise

Joana Filipa Martinho Lopes
2014, supervised by Carmen Freire and Ricardo Pinto.

Patents

We use cookies for marketing activities and to offer you a better experience. By clicking “Accept Cookies” you agree with our cookie policy. Read about how we use cookies by clicking "Privacy and Cookie Policy".