Mariana Braga de Oliveira

Investigador Auxiliar

Supervisões em Curso

Projectos

Ativação metabólica da diferenciação 3D de células estaminais em tecido ósseo (BetterBone)

ParticipanteFundação para a Ciência e a Tecnologia
Estratégias que envolvam a diferenciação osteogénica de células estaminais mesenquimais (MSCs) representam ferramentas promissoras na medicina regenerativa, tanto através da promoção da regeneração in situ, como da implanta&...

Bioengenharia de dispositivos híbridos hierárquicos com capacidade de auto oxigenação (O2CELLS)

ParticipanteFundação para a Ciência e a Tecnologia
A engenharia de tecidos surgiu como uma solução alternativa para fornecer suportes estruturais temporários no local do defeito até que o tecido nativo seja regenerado endogenamente e a função normal seja restaurada. Apesar dos progressos realizados nos últimos 20 anos, ainda não é possível abordar toda a complexidade e propriedades multifunciona...

Exploring devitalized MSCs fibres as immunomodulatory devices for wound regeneration through (i) direct promotion of healing or (ii) enabling of allograft transplantation free of systemic immunosuppression (LAZARUS)

CoordenadorOther International
The project aims at exploring MSCs as constituents of off-the-shelf easy-to-handle immunomodulatory biomaterials. The project focuses on using these materials to treat difficult-to-heal wounds, which may be chronic, or have proneness to become chronic if not properly treated.Two treatment approaches will be explored using devitalized MSC aggrega...

Innovative tools to treat and model complex cancer environments (TheraTools)

ParticipanteEuropean Comission
Funded by the Marie Skłodowska-Curie Actions programme, the TheraTools project will create a multidisciplinary research and training network to focus on the technological development of scientific tools to study malignant tumours localised beyond a biological barrier, as in the case of brain tumours. The TheraTools consortium will provi...

Merging Sustainable and Digital Chemical Technologies for The Development of Greener-Bydesign Pharmaceuticals (SusPharma)

ParticipanteEuropean Comission
Safe- and green-by-design are pre-market design approaches whereby the objectives of minimizing the use of hazardous chemicals, reducing greenhouse gas emissions, and fostering the reuse and recycling of materials in a circular economy are built into product design. SUSPHARMA fits the European need for sustainable development in modern ...

Publicações

An Intracellular Metabolic Signature as a Potential Donor-Independent Marker of the Osteogenic Differentiation of Adipose Tissue Mesenchymal Stem Cells

Bispo, DSC; Jesus, CSH; Romek, K; Marques, IMC; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 23.

Cell Response in Free-Packed Granular Systems

Cunha, AF; Matias, AFV; Dias, CS; Oliveira, MB; Araujo, NAM; Mano, JF
2022, ACS APPLIED MATERIALS & INTERFACES, 14, 36, 40469-40480.

Cell Response in Free-Packed Granular Systems

Ana F. Cunha, André F. V. Matias, Cristóvão S. Dias, Mariana B. Oliveira*, Nuno A. M. Araújo*, João F. Mano*
2022, ACS Applied Materials & Interfaces, 14, 36, S417-S418.

Endo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation

Bispo, DSC; Michalkova, L; Correia, M; Jesus, CSH; Duarte, IF; Goodfellow, BJ; Oliveira, MB; Mano, JF; Gil, AM
2022, CELLS, 11, 8.

NMR Metabolomics Assessment of Osteogenic Differentiation of Adipose-Tissue-Derived Mesenchymal Stem Cells

Bispo, DSC; Jesus, CSH; Correia, M; Ferreira, F; Bonifazio, G; Goodfellow, BJ; Oliveira, MB; Mano, JF; Gil, AM
2022, JOURNAL OF PROTEOME RESEARCH, 21, 3, 654-670.

ONE-STEP ASSEMBLY OF ROBUST ALL-CELLULAR FIBERS

Oliveira, MB; Salvador, T; Sousa, AR; Mano, JF
2022, TISSUE ENGINEERING PART A, 28, S398-S398.

Tricalcium phosphate doped with Mg2+ and combinations of Mn2+, Zn2+ and Fe3+: A DoE study on sintering, mechanical, microstructural and biological properties

Macedo, DF; Cunha, AF; Mano, JF; Oliveira, MB; Silva, AP
2022, CERAMICS INTERNATIONAL, 48, 14, 20467-20477.

Recent advances in the design of implantable insulin secreting heterocellular islet organoids

Akolpoglu, MB; Inceoglu, Y; Bozuyuk, U; Sousa, AR; Oliveira, MB; Mano, JF; Kizilel, S
2021, BIOMATERIALS, 269.
ISBN: 1878-5905

Engineering Strategies for Allogeneic Solid Tissue Acceptance

Sousa, AR; Mano, JF; Oliveira, MB
2021, TRENDS IN MOLECULAR MEDICINE, 27, 6, 572-587.
ISBN: 1471-499X

Strategies for re-vascularization and promotion of angiogenesis in trauma and disease

Goncalves, RC; Banfi, A; Oliveira, MB; Mano, JF
2021, BIOMATERIALS, 269.
ISBN: 1878-5905

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