Paula Cristina Ferreira da Silva Brandão

Investigador Auxiliar

Perfil biográfico

Paula Brandão graduated in Biological Engineer from the University of Minho in 1993.

Completed a phD degree in Inorganic Chemistry with title "Synthesis structure and reactivity of novel microporous materials", from the Department of Chemistry in University of Aveiro in January of 1999.

In February of 1999, started a post-doc position at UMIST/Manchester/England working in project entitled “Catalytic activity of novel heteogeneous microporous catalysts for petroleum industry application”.

Paula Brandão has been a research assistant in the Aveiro institute of Materials (CICECO) since June 2009 until May 2014 and research assistant at TEMA−NRD, Mechanical Engineering Department, University of Aveiro since june 2014 until May 2015.

Actually Paula is responsible for the single crystal X-ray diffraction laboratory, its maintenance, as well as the training of the new users, contributing to the knowledge of the students not only to handle the single crystal X-ray machine but also in solving structures using different methodologies.

Interesses científicos

Simultaneously to the research on crystallography, Paula Brandão started to develop independent research including design, synthesis and characterisation of:

Polinuclear Cu and Fe complexes with different bio-ligands (DNA bases, Vitamin B3 and Vitamin B1), and polypyridyl ligands as alternative anti-tumoral drugs including cytotoxic and DNA studies;

Bio-metal-organic frameworks as potential delivery vehicles for therapeutic nitric oxide;

Multinuclear transition metal compounds (Cu, Co, Mn, and Fe) with important magnetic properties to be used in quantum information at room temperature.

Projectos financiados

- "Novel Smart multi-funcional transition metal-rare earth




 – “Photocatalytic reduction of carbon dioxide into valuable hydrocarbon products” (Financial support PTDC/QUI/72584/2006, from 01-01-2008 to 31-12-2011)

– Mesoporous hybrid organic-inorganic materials– (Financial support POCI/CTM/55648/2004, from 01-05-2006 to 30-04-2009)



Publicações seleccionadas

- S. Banerjee, P. Ghorai, P. Brandão, D. Ghosh, S. Bhuiya, D. Chattopadhyay, S. Das, A. Saha, “Syntheses, crystal structures, DNA binding, DNA cleavage, molecular docking and DFT study of Cu(II) complexes involving N2O4 donor azo Schiff base ligands”, New Journal of Chemistry, 2018, 42, 246-259. DOI: 10.1039/c7nj03293e

- B. Anacleto, P. Gomes, A. Correia-Branco, C. Silva, F. Martel, P. Brandão, “Design, structural characterization and cytotoxic properties of copper (I) and copper (II) complexes formed by vitamin B3 type”, Polyhedron, 2017, 138, 277-286,  DOI:10.1016/j.poly.2017.09.030

- R.V. Pinto, F. Antunes, J. Pires, V. Graça, P. Brandão, M.L. Pinto, “Vitamin B3 metal-organic frameworks as potential delivery vehicles for therapeutic nitric oxide”, Acta Biomateriala, 2017, 51, 66-74, DOI: 10.1016/j.actbio.2017.01.039

- B.J.M.L. Ferreira, P. Brandão,  M. Meireles, F. Martel, A. Correia-Branco, D. M: Fernandes, T.M., Santos, V. Félix, Synthesis, structural characterization, cytotoxic properties and DNA binding of a dinuclear copper(II) complex”, Journal of Inorganic Biochemistry, 2016, 161, 9-17, DOI: 10.1016/j.jinorgbio.2016.04.026

- C. Cruz, D. Soares Pinto, P. Brandão, A. M. dos Santos, M. S. Reis,  “Carboxylate-based molecular magnet: One path toward achieving stable quantum correlations at room temperature”,  EPL, 2016, 113, 40004, DOI: 10.1209/0295-5075/113/40004 

Supervisões em Curso


Controlo da escala de tamanho através de "Chimie Douce": de materiais funcionais inorgânicos a hìbridos orgânicos-inorgânicos (POCTI/CTM/46780/2002)

ParticipanteFundação para a Ciência e a Tecnologia
Materiais Funcionais Inorgânicos Chimie Douce HÌbridos Orgânicos-Inorgânicos Luminescente

Magnetos moleculares: fundamentos e aplicações (Transnational cooperation - Convénio FCT/CAPES 2011-2010)

CoordenadorFundação para a Ciência e a Tecnologia

Materiais mesoporos híbridos orgânicos-inorgânicos (POCI/CTM/55648/2004)

ParticipanteFundação para a Ciência e a Tecnologia
Materiais mesoporosos periódicos híbridos orgânicos-inorgânicos Filmes finos mesoporosos estruturados Catalisadores heterogéneos

Novas estruturas metalo-orgânicas multi-funcuionais inteligentes com metais de transição e terras raras (TROFs), com propiriedades magnéticas e luminescentes sintonizáveis (PTDC/CTM-NAN/119994/2010)

ParticipanteFundação para a Ciência e a Tecnologia
transição metal-terra-rara quadros orgânicos Engenharia de Cristais multi-funcionalidade propriedade físicas

Redução fotocatalítica de dióxido de carbono em hidrocarbonetos sintéticos (PTDC/QUI/72584/2006)

ParticipanteFundação para a Ciência e a Tecnologia
Fotocatálise Dióxido de carbono Fotoredução electroredução

Síntese de Silicatos Luminescentes Utilizando Complexos de Lantanideos como Agentes Directores de Estrutura (POCI/CTM/58863/2004)

ParticipanteFundação para a Ciência e a Tecnologia
Materias Funcionais Inorgânicos Luminescência Silicatos Microporosos Complexos de Lantanídeos

Síntese e Caracterização de novas membranas de Niobiossilicatos e Titanossilicatos Microporosos e a sua aplicação na separação de misturas contendo hidrogénio (PTDC/EQU-EQU/100476/2008)

ParticipanteFundação para a Ciência e a Tecnologia
Separação de Hidrogénio Membranas Titanossilicatos Niobiossilicatos


Proton controlled synthesis of two dicopper(II) complexes and their magnetic and biomimetic catalytic studies together with probing the binding mode of the substrate to the metal center

Jana, NC; Ghorai, P; Brandao, P; Jaglicic, Z; Panja, A
2021, DALTON TRANSACTIONS, 50, 42, 15233-15247.
ISBN: 1477-9234

New heptacoordinate tungsten(II) complexes with α-diimine ligands in the catalytic oxidation of multifunctional olefins

Vasconcellos-Dias, M; Nunes, CD; Felix, V; Brandao, P; Calhorda, MJ
ISBN: 1873-3255

A novel triple aqua-, phenoxo- and carboxylato-bridged dinickel(II) complex, its magnetic properties, and comparative biomimetic catalytic studies with analogous dinickel(II) complexes

Jana, NC; Jaglicic, Z; Brandao, P; Adak, S; Saha, A; Panja, A
2021, NEW JOURNAL OF CHEMISTRY, 45, 17, 7602-7613.
ISBN: 1369-9261

Synthesis, structure elucidation and dft study of a new thiazole-pyridine anchored nnn donor and it's cobalt(II) complex: In-vitro antitumor activity against U937 cancer cells, dna binding property and molecular docking study

Bera, P; Aher, A; Brandao, P; Manna, SK; Bhattacharyya, I; Pramanik, C; Mandal, B; Das, S; Bera, P
ISBN: 1872-8014

Tuneable structures and magnetic properties of pseudohalo-bridged dinuclear Ni(II) complexes derived from {N-4} and {N3O} donor ligands

Adak, S; Sun, YC; Jana, NC; Brandao, P; Wang, XY; Panja, A
2021, CRYSTENGCOMM, 23, 18, 3371-3382.
ISBN: 1466-8033

Anticancer activity, DNA binding and docking study of M(II)-complexes (M = Zn, Cu and Ni) derived from a new pyrazine-thiazole ligand: synthesis, structure and DFT

Bera, P; Aher, A; Brandao, P; Manna, SK; Bhattacharyya, I; Mondal, G; Jana, A; Santra, A; Bera, P
2021, NEW JOURNAL OF CHEMISTRY, 45, 27, 11999-12015.
ISBN: 1369-9261

A polynuclear Cu(ii) complex for real time monitoring of mitochondrial cytochromeCrelease during cellular apoptosis

Khanra, S; Ta, S; Paladhi, A; Ghosh, M; Ghosh, S; Hira, SK; Manna, PP; Brandao, P; Felix, V; Das, D
2020, CHEMICAL COMMUNICATIONS, 56, 48, 6563-6566.
ISBN: 1364-548X

Combined experimental and computational studies on preferential CO2 adsorption over a zinc-based porous framework solid

Saha, D; Gayen, S; Maity, T; Frontera, A; Ortega-Castro, J; Leus, K; Wang, GB; Van Der Voort, P; Brandao, P; Koner, S
2020, NEW JOURNAL OF CHEMISTRY, 44, 5, 1806-1816.
ISBN: 1369-9261

Efficient Visible-Light-Excitable Eu3+ Complexes for Red Organic Light-Emitting Diodes

Francis, B; Nolasco, MM; Brandao, P; Ferreira, RAS; Carvalho, RS; Cremona, M; Carlos, LD
ISBN: 1099-0682

Induced apoptosis against U937 cancer cells by Fe(II), Co(III) and Ni(II) complexes with a pyrazine-thiazole ligand: Synthesis, structure and biological evaluation

Bera, P; Aher, A; Brandao, P; Manna, SK; Mondal, G; Jana, A; Santra, A; Jana, H; Bera, P
2020, POLYHEDRON, 182.

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